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Britt J van Keulen Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Endocrinology, Amsterdam, The Netherlands

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Conor V Dolan Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

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Bibian van der Voorn Department of Pediatric Endocrinology, Sophia Kinderziekenhuis, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

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Ruth Andrew Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, UK

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Brian R Walker Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, UK
Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK

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Hilleke Hulshoff Pol Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands

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Dorret I Boomsma Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

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Joost Rotteveel Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Endocrinology, Amsterdam, The Netherlands

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Martijn J J Finken Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Endocrinology, Amsterdam, The Netherlands

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). Interaction between gonadal steroids and the metabolism of cortisol has been suggested by several studies ( 21 , 22 , 23 , 24 ). However, there is only one cross-sectional study that has investigated glucocorticoid metabolism in children of various ages

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0123
Volume/Issue:
Volume 9: Issue 6
Open access
Lukas Engler Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Christian Adolf Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Daniel A Heinrich Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Anna-Katharine Brem Max-Planck-Institute of Psychiatry, Munich, Germany
Division of Interventional Cognitive Neurology, Department of Neurology, Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

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Anna Riester Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Anna Franke Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Felix Beuschlein Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Martin Reincke Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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Axel Steiger Max-Planck-Institute of Psychiatry, Munich, Germany

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Heike Künzel Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU München, Munchen, Germany

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, 4 ); however, the underlying pathophysiology is not fully clarified. Animal data emphasize the importance of a balanced MR/glucocorticoid receptor (GR) system for cognitive functions ( 5 ) and support the role of MR in memory functions. Furthermore

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0043
Volume/Issue:
Volume 8: Issue 4
Open access
Henrik H Thomsen Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark

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Holger J Møller Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark

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Christian Trolle Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark

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Kristian A Groth Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark

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Anne Skakkebæk Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark

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Anders Bojesen Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark

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Christian Høst Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark

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Claus H Gravholt Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark

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of plasma hemoglobin through endocytosis of the very high-affinity complex hemoglobin–haptoglobin, thus preventing the oxidative stress from free hemoglobin by the release of the free iron, bilirubin, and carbon monoxide. Glucocorticoids and anti

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-13-0067
Volume/Issue:
Volume 2: Issue 4
Open access
Amit Kumar Department of Medicine, Christian Medical College and Hospital, Ludhiana, Punjab, India

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Maria Ghosh Department of Biochemistry, Christian Medical College and Hospital, Ludhiana, Punjab, India

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Jubbin Jagan Jacob Department of Endocrinology, Christian Medical College and Hospital, Ludhiana, Punjab, India

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glucocorticoids either as part of local remedies or as injectables by unqualified medical practitioners ( 16 ). The second reason being an increased prevalence of undiagnosed hypopituitarism among older menopausal women due to post-partum pituitary necrosis

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0500
Volume/Issue:
Volume 10: Issue 12
Open access
Yan-yu Zhang Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China

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Xian Zhang Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China

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Shao-yang Bu Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China

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Wei-wei Zhang Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China

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Tian-xiu Li Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China

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De-cai Zheng Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China

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Ze-xiang Huang Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China

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Qian Wang Department of Aquaculture, College of Marine Sciences, Hainan University, Haikou, Hainan, China

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via glucocorticoid and then participate in the regulation of gonadal differentiation and sexual reversal. However, the distribution of two kiss -expressing neurons in the brain of sexual reversal teleosts has been poorly studied. The yellowtail

Article Type:
Research Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-22-0136
Volume/Issue:
Volume 11: Issue 8
Open access
Saroj Kumar Sahoo Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Division of Endocrinology, Mid and South Essex NHS Trust, Broomfield, UK

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Jayakrishnan C Menon Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

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Nidhi Tripathy Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

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Monalisa Nayak Department of Liver Intensive Care Unit, King’s College Hospital, London, UK

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Subhash Yadav Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

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adrenocorticotrophic hormone (ACTH) ( 11 ). The LD-SST has an advantage at this early stage of secondary AI, but it may suffer from performance error and resultant false-negative test ( 11 , 12 , 13 ). Glucocorticoids have been the mainstay of treatment of severe

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-24-0086
Volume/Issue:
Volume 13: Issue 9
Open access
Martin Wiegand MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK

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David J Halsall Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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Sarah L Cowan Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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Kevin Taylor Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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Robert J B Goudie MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, Cambridge, UK

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Jacobus Preller Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK

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Mark Gurnell Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
Wellcome–MRC Institute of Metabolic Science, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Addenbrooke’s Hospital, Cambridge, UK

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our analysis if the blood sample was collected after the patient had already received glucocorticoid or mineralocorticoid therapy (e.g. dexamethasone, fludrocortisone, hydrocortisone, methylprednisolone, prednisolone). Following the findings of the

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-22-0190
Volume/Issue:
Volume 11: Issue 11
Open access
Amir Bashkin Department of Endocrinology, Galilee Medical Center, Nahariya, Israel
Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel

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Eliran Yaakobi Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel

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Marina Nodelman Department of Endocrinology, Galilee Medical Center, Nahariya, Israel
Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel

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Ohad Ronen Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel
Department of Otolaryngology Head and Neck Surgery, Galilee Medical Center, Nahariya, Israel

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glucocorticoids, levothyroxine, Mercaptizol, Propylthiouracil, Amiodarone, opioids and drugs that enhance T4 metabolism through the enhancement of cytochrome P450 3A4 such as phenytoin and carbamazepine ( 5 , 6 ). Patients were divided into the following

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0004
Volume/Issue:
Volume 7: Issue 4
Open access
Johanna Christina Penell Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden
Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden

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Mark M Kushnir Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA
ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA

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Lars Lind Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden

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Jonatan Bergquist Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden

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Jonas Bergquist Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, USA
Department of Chemistry – BMC, Analytical Chemistry, Uppsala University, Uppsala, Sweden

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P Monica Lind Department of Medical Sciences, Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden

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Tord Naessen Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden

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( n  = 3, all women), persons on hormone replacement therapy ( n women  = 243, n men = 19) and persons on glucocorticoid therapy ( n women = 6, n men = 4). Statistical significant difference between men and women as evaluated by chi

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0045
Volume/Issue:
Volume 10: Issue 5
Open access
Hong Jiang Department of Neurosurgery, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department of Neurosurgery, Rui-Jin Lu-Wan Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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WenJie Yang Department of Radiology, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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QingFang Sun Department of Neurosurgery, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department of Neurosurgery, Rui-Jin Lu-Wan Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Chang Liu The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu, China
College of Information Technology and Engineering, Chengdu University, Chengdu, China
College of Computer Science, Sichuan Normal University, Chengdu, Sichuan, China

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LiuGuan Bian Department of Neurosurgery, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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mineralocorticoid receptors (MRs), to which both mineralocorticoids and glucocorticoids can bind ( 20 ). Experimental animal studies have already demonstrated the neurotoxic effects of hypercortisolism on the limbic system ( 21 ). Previous studies of CD patients

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0385
Volume/Issue:
Volume 10: Issue 11
Open access