Yali Cheng
Yali Cheng
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Qiaoying Lv
Qiaoying Lv
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Bingying Xie
Bingying Xie
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Bingyi Yang
Bingyi Yang
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Weiwei Shan
Weiwei Shan
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Chengcheng Ning
Chengcheng Ning
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Bing Li
Bing Li
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Liying Xie
Liying Xie
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Chao Gu
Chao Gu
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Xuezhen Luo
Xuezhen Luo
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Xiaojun Chen
Xiaojun Chen
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Qin Zhu
Qin Zhu
Department of Pathology, Obstetrics and Gynecology, Hospital of Fudan University, Shanghai, China
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– 294 . ( https://doi.org/10.1002/ijc.28679 ) 10.1002/ijc.28679 24347287 10 Barry JA Azizia MM Hardiman PJ . Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta
Laura Chioma
Laura Chioma
Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
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Carla Bizzarri
Carla Bizzarri
Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
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Martina Verzani
Martina Verzani
Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
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Daniela Fava
Daniela Fava
Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Mariacarolina Salerno
Mariacarolina Salerno
Paediatric Endocrinology Unit, Department of Translational Medical Sciences, University of Naples Federico II, Naples, Italy
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Donatella Capalbo
Donatella Capalbo
Paediatric Endocrinology Unit, Department of Mother and Child, University Hospital Federico II, Naples, Italy
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Chiara Guzzetti
Chiara Guzzetti
Paediatric Endocrine Unit, Paediatric Hospital Microcitemico ‘A. Cao’, AO Brotzu, Cagliari, Italy
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Laura Penta
Laura Penta
Pediatric Clinic, Department of Medicine and Surgery, University of Perugia, Perugia, Italy
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Luigi Di Luigi
Luigi Di Luigi
Endocrinology Unit, Department of Movement, Human and Health Sciences, University of Rome ‘Foro Italico’, Rome, Italy
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Natascia di Iorgi
Natascia di Iorgi
Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Mohamad Maghnie
Mohamad Maghnie
Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genova, Italy
Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genova, Italy
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Sandro Loche
Sandro Loche
Paediatric Endocrine Unit, Paediatric Hospital Microcitemico ‘A. Cao’, AO Brotzu, Cagliari, Italy
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Marco Cappa
Marco Cappa
Endocrinology Unit, University Pediatric Department, Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy
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L Sorensen K Petersen JH Skakkebaek NE Juul A . Recent decline in age at breast development: the Copenhagen Puberty Study . Pediatrics 2009 123 e932 – e939 . ( https://doi.org/10.1542/peds.2008-2491 ) 8 Heras V Castellano JM
A Bergougnoux
A Bergougnoux
Service de Génétique Moléculaire et de Cytogénétique, Centre Hospitalier Universitaire de Montpellier, Université de Montpellier, Montpellier, France
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L Gaspari
L Gaspari
Département d'Endocrinologie et de Gynécologie Pédiatrique, Hôpital Arnaud de Villeneuve, Université de Montpellier, Montpellier, France
INSERM Unité 1203 (DEFE), Université de Montpellier, Montpellier, France
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INSERM Unité 1203 (DEFE), Université de Montpellier, Montpellier, France
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M Soleirol
M Soleirol
Département de Pediatrie, CHU Nîmes, France, Université de Montpellier Faculté de Médecine Montpellier-Nîmes, Montpellier, France
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N Servant
N Servant
Service de Génétique Moléculaire et de Cytogénétique, Centre Hospitalier Universitaire de Montpellier, Université de Montpellier, Montpellier, France
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S Soskin
S Soskin
Département de Pédiatrie, Centre Hospitalier Universitaire Hautepierre de Strasbourg, Strasbourg, France
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S Rossignol
S Rossignol
Département de Pédiatrie, Centre Hospitalier Universitaire Hautepierre de Strasbourg, Strasbourg, France
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K Wagner-Mahler
K Wagner-Mahler
Département de Pédiatrie, CHU Nice, Hôpitaux Pédiatriques de Nice CHU-Lenval, Nice, France
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J Bertherat
J Bertherat
Department of Endocrinology, French Reference Center for Rare Adrenal Disorders, Hôpital Cochin, Université Paris Cité, Institut Cochin, Assitance Publique-Hôpitaux de Paris, Paris, France
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C Sultan
C Sultan
Département d'Endocrinologie et de Gynécologie Pédiatrique, Hôpital Arnaud de Villeneuve, Université de Montpellier, Montpellier, France
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N Kalfa
N Kalfa
Department of Pediatric Urological Surgery, French Reference Center for abnormalities of Genital Development (DevGen), CHU Lapeyronie, Montpellier University, Montpellier, France
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F Paris
F Paris
Service de Génétique Moléculaire et de Cytogénétique, Centre Hospitalier Universitaire de Montpellier, Université de Montpellier, Montpellier, France
Département d'Endocrinologie et de Gynécologie Pédiatrique, Hôpital Arnaud de Villeneuve, Université de Montpellier, Montpellier, France
INSERM Unité 1203 (DEFE), Université de Montpellier, Montpellier, France
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Département d'Endocrinologie et de Gynécologie Pédiatrique, Hôpital Arnaud de Villeneuve, Université de Montpellier, Montpellier, France
INSERM Unité 1203 (DEFE), Université de Montpellier, Montpellier, France
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. Pubertal development was assessed using the pubic hair (P) and breast (B) development stages 1–5 of the Tanner scale ( 21 ). Hirsutism was quantified using the modified Ferriman–Gallwey (FG) scoring system that includes nine androgen-sensitive body areas
Renea A Taylor
Renea A Taylor
Department of Physiology, Cancer Program and Obesity and Metabolic Disease Program, Biomedicine Discovery Institute, Monash University, Wellington Road, Victoria 3800, Australia
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Jennifer Lo
Jennifer Lo
Department of Physiology, Cancer Program and Obesity and Metabolic Disease Program, Biomedicine Discovery Institute, Monash University, Wellington Road, Victoria 3800, Australia
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Natasha Ascui
Natasha Ascui
Department of Physiology, Cancer Program and Obesity and Metabolic Disease Program, Biomedicine Discovery Institute, Monash University, Wellington Road, Victoria 3800, Australia
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Matthew J Watt
Matthew J Watt
Department of Physiology, Cancer Program and Obesity and Metabolic Disease Program, Biomedicine Discovery Institute, Monash University, Wellington Road, Victoria 3800, Australia
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approximately one-third of cancer-related deaths in 2012 (8) . Obesity contributes to both the increased incidence and/or progression of many cancers including endometrial, bowel, (postmenopausal) breast and prostate cancer (9) . While there is an association
Satoshi Inoue
Satoshi Inoue
Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA
James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Taichi Mizushima
Taichi Mizushima
Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA
James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Hiroki Ide
Hiroki Ide
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Guiyang Jiang
Guiyang Jiang
Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA
James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
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James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
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Takuro Goto
Takuro Goto
Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA
James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
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James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
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Yujiro Nagata
Yujiro Nagata
Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA
James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
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James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
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George J Netto
George J Netto
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
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James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
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Hiroshi Miyamoto
Hiroshi Miyamoto
Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA
James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Department of Urology, University of Rochester Medical Center, Rochester, New York, USA
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James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Department of Urology, University of Rochester Medical Center, Rochester, New York, USA
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cancer ( 21 ). Interestingly, loss of ATF2 function has also been observed in other malignancies, such as breast and lung carcinomas as well as neuroblastoma ( 22 ), implying that the balance of tissue-specific compositions of ATF2-AP1 dimers is critical
Corina Verónica Sasso
Corina Verónica Sasso
Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), CCT-Mendoza CONICET, Mendoza, Argentina
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Flavia Eliana Santiano
Flavia Eliana Santiano
Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), CCT-Mendoza CONICET, Mendoza, Argentina
Universidad de Mendoza, Mendoza, Argentina
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Universidad de Mendoza, Mendoza, Argentina
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Fiorella Campo Verde Arboccó
Fiorella Campo Verde Arboccó
Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), CCT-Mendoza CONICET, Mendoza, Argentina
Universidad de Mendoza, Mendoza, Argentina
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Universidad de Mendoza, Mendoza, Argentina
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Leila Ester Zyla
Leila Ester Zyla
Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), CCT-Mendoza CONICET, Mendoza, Argentina
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Silvana Noemí Semino
Silvana Noemí Semino
Hospital Universitario, Universidad Nacional de Cuyo, Mendoza, Argentina
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Martin Eduardo Guerrero-Gimenez
Martin Eduardo Guerrero-Gimenez
Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), CCT-Mendoza CONICET, Mendoza, Argentina
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Virginia Pistone Creydt
Virginia Pistone Creydt
Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), CCT-Mendoza CONICET, Mendoza, Argentina
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Constanza Matilde López Fontana
Constanza Matilde López Fontana
Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), CCT-Mendoza CONICET, Mendoza, Argentina
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Rubén Walter Carón
Rubén Walter Carón
Instituto de Medicina y Biología Experimental de Cuyo (IMBECU), CCT-Mendoza CONICET, Mendoza, Argentina
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oncogenic effects of estrogens have been widely studied in breast and ovarian cancer, but little is known about its action in colon cancer ( 6 ). Regarding their receptors, it is known that estrogen receptor beta (ERB) is the predominant isoform in the colon
Rebeca Esquivel-Zuniga
Rebeca Esquivel-Zuniga
Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA
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Alan D Rogol
Alan D Rogol
Department of Pediatrics, University of Virginia, Charlottesville, Virginia, USA
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subsequent production of sex steroids, non-steroidal factors and gametes ( 1 , 2 ). Although the HPG axis awakens in late childhood, the external signs of pubertal maturation: early breast development (Tanner stage II) and an increase in testicular volume
Legh Wilkinson
Legh Wilkinson
Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa
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Nicolette J D Verhoog
Nicolette J D Verhoog
Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa
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Ann Louw
Ann Louw
Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa
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-small-cell lung cancer (NSCLC), breast cancer B-lineage leukaemia, T-ALL resistant, lymphoblasts, T-leukaemic, multiple myeloma, human carcinoma, lung adenocarcinoma cells, breast tissue Reduced Reduced GC-resistant ALLGC-resistant MM and diminished GC
Yuan Liu
Yuan Liu
Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China
Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Siyi Guo
Siyi Guo
Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China
Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Jinsong Wu
Jinsong Wu
Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China
Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Rongai Wang
Rongai Wang
Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China
Health Management Center, The Second Affiliated Hospital of Zhejiang Chinese Medicine University, Zhejiang, China
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Health Management Center, The Second Affiliated Hospital of Zhejiang Chinese Medicine University, Zhejiang, China
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Jinbo Liu
Jinbo Liu
Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China
Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Yan Liu
Yan Liu
Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China
Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Bin Lv
Bin Lv
Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, China
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Nan Liu
Nan Liu
Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, China
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Ling Jiang
Ling Jiang
Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China
Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Xiaoli Zhang
Xiaoli Zhang
Department of Endocrinology, Qilu Hospital of Shandong University, Jinan, China
Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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Institute of Endocrine and Metabolic Diseases of Shandong University, Jinan, China
Key Laboratory of Endocrine and Metabolic Diseases, Shandong Province Medicine & Health, Jinan, China
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PHPT, and another five were newly diagnosed with papillary thyroid carcinoma (PTC) during pre-PTX examinations. Of these 42 patients, 27 had PTC, and diagnoses for the remainder included breast cancer ( n = 4), lymphoma ( n = 3), endometrial carcinoma
Ling Zhou
Ling Zhou
Cangzhou Central Hospital, Cangzhou, Hebei, China
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Ruixue Zhang
Ruixue Zhang
Cangzhou Central Hospital, Cangzhou, Hebei, China
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Shuangyan Yang
Shuangyan Yang
Cangzhou Central Hospital, Cangzhou, Hebei, China
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Yaguang Zhang
Yaguang Zhang
Cangzhou Central Hospital, Cangzhou, Hebei, China
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Dandan Shi
Dandan Shi
Cangzhou Central Hospital, Cangzhou, Hebei, China
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( 1 , 2 , 3 ), therefore AS-IV has been widely used to treat hypertension ( 4 , 5 ), cardiovascular diseases ( 6 , 7 ), breast cancer ( 8 ) and cervical cancer ( 9 ). Moreover, numerous publications have demonstrated that AS-IV could protect
