Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
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Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK
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Centre for Endocrinology, William Harvey Research Institute, Barts and The London Medical School, Queen Mary University of London, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK
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Department of Paediatric Endocrinology, Makarios Children's Hospital, Nicosia, Cyprus
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Sussex Community NHS Trust, Brighton, UK
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Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
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The University of Dublin, Trinity College Dublin, Dublin, Republic of Ireland
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-like growth factor (IGF)-I in children with PWS . Journal of Clinical Medicine 2022 11 1280 . ( https://doi.org/10.3390/jcm11051280 ) 88 Palmieri VV Lonero A Bocchini S Cassano G Convertino A Corica D Crinò A Fattorusso V Ferraris S
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childhood, followed by a sharp acceleration from the onset of puberty onward, up to early adulthood. During puberty, the growth hormone (GH)/insulin-like growth factor (IGF)-1 axis and sex steroids become the main determinants of bone development, acting on
Endocrinology Department, University Hospital in Krakow, Krakow, Poland
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Endocrinology Department, University Hospital in Krakow, Krakow, Poland
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Endocrinology Department, University Hospital in Krakow, Krakow, Poland
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Unluhizarci K Casanueva F Kelestimur F. Body Composition, serum IGF-I and leptin level changes in amateur boxers: retired boxers have risk factors for cardiovascular disorders . Obesity and Metabolism 2008 4 118 – 123 . 93 Hannon MJ Crowley
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Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
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Department of Pediatric Oncology/Hematology, Amsterdam University Medical Center, location VU University Medical Center, Amsterdam, The Netherlands
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Department of Pediatrics, Emma Children’s Hospital, Amsterdam University Medical Center, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
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assessed, and the clinical consequences of declining FT4 concentrations in these patients remain unclear. To this end, we retrospectively analyzed the incidence and latency time of ‘diagnosed’ central hypothyroidism (i.e., FT4 concentrations below those of
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diagnosed with acromegaly eight had elevated serum insulin-like growth factor 1 (IGF-I) concentrations ( z -score between 4 and 12). Details on other hormone replacement therapies are given in Table 1 . Table 2 Hormone levels and semen quality
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auxological and/or other clinical features suggestive of GHD ( 14 ) and IGF-1 concentration <0 s.d. (reference ranges standardized for age and sex), GHD was confirmed by GH stimulation tests. Two different stimulation tests (clonidine and insulin hypoglycemia
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least three of the following: (i) overweight and/or obesity, that is, BMI ≥ 25.0 kg/m 2 ; (ii) hyperglycemia, that is, fasting glycemia ≥ 6.1 mmol/L and/or postprandial 2 h blood glucose ≥ 7.8 mmol/L and/or diagnosis of and treatment for diabetes; (iii
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-visualized posterior pituitary; TPP, topic posterior pituitary lobe. Serum levels of TSH, GH, LH, FSH, PRL, cortisol, dehydroepiandrosterone sulphate, total thyroxine, free thyroxine, insulin-like growth factor 1 (IGF-1), oestradiol or testosterone levels
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activation. Morover, the drug was able to increase the expression of G-protein-coupled receptors (GPCRs) (i.e. somatostatin receptors) and tyrosine-kinase receptors (TRKs) (i.e. insulin and IGF-1 receptors) in the same cells ( 46 ). See related text paragraph
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worse response to treatment with SST2-specific SSA compared with AIP wild-type acromegaly controls, both in terms of smaller IGF-1 decreases and less tumor shrinkage. In acromegaly patients without AIP mut, it has also been suggested that AIP