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risk of metabolic syndrome and type 2 diabetes . Journal of Clinical Endocrinology and Metabolism 2015 100 4595 – 4603 . ( https://doi.org/10.1210/jc.2015-2546 ) 10.1210/jc.2015-2546 35 Daka B Langer RD Larsson CA Rosen T Jansson PA Rastam L
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( 18 ) and cardiovascular diseases ( 19 , 20 ). Additionally, there is accumulative evidence that elevated serum CysC levels are responsible for incidence of metabolic syndrome and T2D ( 21 , 22 , 23 ). Those metabolic diseases and their related
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). As a co-receptor of Wnt, LRP6 plays a critical role in the Wnt/β-catenin pathway. Genetic studies have revealed that the variations of LRP6 genes are associated with the susceptibility of a plethora of diseases, including metabolic syndrome, T2DM
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long-term consequences, such as to increase the risk of metabolic syndrome ( 11 , 12 ) and secondary osteoporosis ( 13 ). Adolescents affected by pubertal delay often feel distressed by their condition. This may have an important impact on quality of
Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
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Department of Clinical Genetics and Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark
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Unit for Thrombosis Research, Hospital of South West Jutland and University of Southern Denmark, Esbjerg, Denmark
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Department of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
Unit for Thrombosis Research, Hospital of South West Jutland and University of Southern Denmark, Esbjerg, Denmark
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morbidity and mortality are well described in KS. Hypergonadotropic hypogonadism is one of the most frequent issues in KS patients, resulting in infertility and accelerating metabolic syndrome, with 90–100% of KS patients having elevated gonadotropins
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Pichiah PBT & Cha YS . Vitamin D and metabolic diseases: growing roles of vitamin D . Journal of Obesity and Metabolic Syndrome 2018 27 223 – 232 . ( https://doi.org/10.7570/jomes.2018.27.4.223 ) 9 Hossein-nezhad A & Holick MF . Vitamin D
Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland
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The Key Laboratory of Systems Biomedicine, Ministry of Education, and Exercise Translational Medicine Center, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China
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Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland
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Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland
The Key Laboratory of Systems Biomedicine, Ministry of Education, and Exercise Translational Medicine Center, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China
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Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland
Department of Epidemiology and Biostatistics, Centre for Environment and Health, School of Public Health, Imperial College London, London, UK
Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland
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age of 14 predicted development of metabolic syndrome 10 years later ( 30 ). Our results complement the above-cited studies by demonstrating inverse associations between serum SHBG, adiposity and insulin resistance from childhood to early adulthood
Department of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu, China
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AK Singh A Jain A Patra SK Goswami B Bhatnagar MK Bhatacharjee J . Raised TSH is associated with endothelial dysfunction in Metabolic Syndrome: a case control study . Romanian Journal of Internal Medicine 2017 55 212 – 221 . ( https
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insulin resistance ( 22 , 23 , 24 , 25 ). However, other findings indicate that circulating Nrg4 concentrations may be a protective factor in the development of metabolic syndrome. For instance, in newly diagnosed patients with type 2 diabetes, lower
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physiological and hormonal circumstances ( 32 ), and further studies are needed to address this issue. Metabolic syndrome (MetS) is a frequent clinical condition in hypertensive patients especially in PA patients ( 33 ). In addition, APA and IHA may have