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Klaudia Zajkowska Endocrinology, Holycross Cancer Centre, Kielce, Poland

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Janusz Kopczyński Surgical Pathology, Holycross Cancer Centre, Kielce, Poland

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Stanisław Góźdź Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland

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Aldona Kowalska Endocrinology, Holycross Cancer Centre, Kielce, Poland
Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland

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observed difference in NIFTP prevalence between Asian and non-Asian countries can be attributed to ethnic variance (different mutation profiles of thyroid cancer) ( 23 ), differences in the interpretation of histological criteria ( 24 ) and differences in

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Jia Liu Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Min Liu Department of Radiology, China-Japan Friendship Hospital, Beijing, China

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Zhe Chen Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Yumei Jia Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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Guang Wang Department of Endocrinology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

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heterogeneous thyroid in a thyroid ultrasound ( 12 ). Individuals with systemic inflammatory disease, cancer, claustrophobia and metal implants were excluded. No subject had been administered levothyroxine or antithyroid drugs. Individuals who were pregnant

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Weidi Wang Department of Emergency, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China

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Lingjun Kong Department of Thyroid and Breast, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China

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Hongkun Guo Department of Emergency, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China

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Xiangjin Chen Department of Thyroid and Breast, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China

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patients. Studies were excluded if (i) they were case reports, reviews, conference abstracts, and posters; (ii) patients with other pathologic types of thyroid carcinoma or preoperatively bilateral thyroid cancer; (iii) patients who had undergone head and

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Lauren E Henke Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, USA

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John D Pfeifer Department of Pathology, Washington University School of Medicine, St. Louis, Missouri, USA

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Thomas J Baranski Division of Endocrinology, Diabetes, and Metabolism, Department of Internal Medicine, Washington University School of Medicine, Saint Louis, Missouri, USA

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Todd DeWees Division of Biomedical Statistics and Informatics, Mayo Clinic, Scottsdale, Arizona, USA

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Perry W Grigsby Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri, USA
Division of Nuclear Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, Missouri, USA

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Protection Office at Washington University School of Medicine, including retrospective chart review (protocol number 201010705) with waiver of consent. Records of 1712 patients with invasive thyroid cancer who were referred to the Department of Radiation

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Xiaoya Zheng Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Shanshan Yu Pathology Department, Chongqing Medical University, Chongqing, China

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Jian Long Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Qiang Wei Prevention of Disease Department, Chongqing Jiulongpo District Hospital of Traditional Chinese Medicine, Chongqing, China

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Liping Liu Department of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Chun Liu Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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Wei Ren Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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to PTL, DSVPTC had a higher incidence of lymph node metastasis (82.5% vs 30.8%, P   < 0.001). There were no significant differences in radiation exposure history or thyroid cancer family history between the two groups ( P   > 0.05). Figure 1

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Ya Zhang Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Xiaoqiu Chu Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Yuling Liu Department of Endocrinology, Zaozhuang Municipal Hospital, Zaozhuang, China

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Yueting Zhao Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Xue Han Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Xin Hu Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Pingping Xiang Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Guofang Chen Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Chao Liu Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China
Key Laboratory of TCM Syndrome and Treatment of Yingbing (Thyroid Disease) of State Administration of Traditional Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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Shuhang Xu Endocrine and Diabetes Center, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China

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with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer . Thyroid 2016 26 1 – 133 . ( https://doi.org/10.1089/thy.2015.0020 ) 15 Kobaly K

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Zhenzhen Wang Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China

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Xiangying Zhu Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China

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Xiaohui Yu Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China

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Haixia Guan Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China

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Lei Zhao Department of Ultrasonography, The First Affiliated Hospital of China Medical University, Shenyang, China

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Yixia Zhang Department of Ultrasonography, The First Affiliated Hospital of China Medical University, Shenyang, China

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Yuge Li Department of Ultrasonography, The First Affiliated Hospital of China Medical University, Shenyang, China

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Liang Sang Department of Ultrasonography, The First Affiliated Hospital of China Medical University, Shenyang, China

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Yuchen Han Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China

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Yushu Li Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China

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Zhongyan Shan Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China

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Weiping Teng Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China

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). The ‘2015 American Thyroid Association (ATA) Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer’ (referred to as the ATA classification) ( 26 ) more comprehensively defines the ultrasound features and risk

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Yun Hu Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China
Department of Immunology, Nanjing Medical University, Jiangsu, China

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Na Li Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China

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Peng Jiang Department of Thyroid and Breast Surgery, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China

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Liang Cheng Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China

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Bo Ding Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China

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Xiao-Mei Liu Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China

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Ke He Department of Endocrinology, Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Jiangsu, China

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Yun-Qing Zhu Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China

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Bing-li Liu Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China

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Xin Cao Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China

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Hong Zhou Department of Immunology, Nanjing Medical University, Jiangsu, China

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Xiao-Ming Mao Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Jiangsu, China

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relationship between thyroid nodule and thyroid cancer ( 3 , 4 ). Thyroid nodules are usually accompanied by an increase in thyroglobulin (Tg) ( 5 , 6 ) and autoimmune thyroid diseases (AITDs), especially Hashimoto’s thyroiditis (HT) ( 7 , 8 ). Interestingly

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Ling Hu Department of Endocrinology, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

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Ting Li Department of Endocrinology, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

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Xiao-Ling Yin Department of Endocrinology, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

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Yi Zou Department of Endocrinology, The Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China

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Introduction Both solitary and multiple thyroid nodules (TN) are very commonly seen in clinical practice; this is important, because thyroid cancer occurs in approximately 5% of these nodules ( 1 ). Thyroid nodules can also indicate thyroid

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Aleksandra Kukulska Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland
Radiotherapy Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Jolanta Krajewska Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Zofia Kolosza Department of Epidemiology and Silesia Cancer Registry, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Ewa Paliczka-Cieslik Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Aleksandra Kropinska Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Agnieszka Pawlaczek Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Zbigniew Puch Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Kornelia Ficek Radiotherapy Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Teresa Lisik Radiotherapy Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Dorota Sygula Radiotherapy Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Zbigniew Wygoda Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Jozef Roskosz Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Jerzy Wydmanski Radiotherapy Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Barbara Jarzab Nuclear Medicine and Endocrine Oncology Department, M. Sklodowska-Curie Institute – Oncology Center, Gliwice Branch, Gliwice, Poland

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Introduction Medullary thyroid carcinoma (MTC) is a rarely diagnosed malignant neoplasm arising from C cells and constitutes only 5% of all thyroid cancers. MTC may occur as a sporadic disease or as part of hereditary multiple endocrine

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