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Waleed K W Al-Badri Orbital center Amsterdam, Department of Ophthalmology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands

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Hinke Marijke Jellema Orbital center Amsterdam, Department of Ophthalmology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands

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Arnaud R G G Potvin Orbital center Amsterdam, Department of Ophthalmology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands

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Ruth M A van Nispen Amsterdam University Medical Center, Vrije Universiteit, Department of Ophthalmology, Amsterdam Public Health research institute, Amsterdam, the Netherlands

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Peter H Bisschop Department of Endocrinology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands

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Peerooz Saeed Orbital center Amsterdam, Department of Ophthalmology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands

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thyrotoxicosis ( 33 , 54 , 56 , 57 ) The role of stress in the onset of GD Many studies have been conducted on the influence of psychological stress on the onset of GD. Retrospective studies found that GD patients reported more negative life

Article Type:
Review Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-24-0259
Volume/Issue:
Volume 13: Issue 9
Open access
Nancy Martini Laboratorio de Investigaciones en Osteopatías y Metabolismo Mineral (LIOMM-UNLP-CICPBA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

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Lucas Streckwall Laboratorio de Investigaciones en Osteopatías y Metabolismo Mineral (LIOMM-UNLP-CICPBA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

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Antonio Desmond McCarthy Laboratorio de Investigaciones en Osteopatías y Metabolismo Mineral (LIOMM-UNLP-CICPBA), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina

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atheromatous lesions and a high thrombotic risk. Taken together, while osteoporosis and osteopenia increase the risk of low-stress or fragility bone fractures ( 3 ), AC loading increases the risk of stroke, dementia, myocardial infarction, heart failure, renal

Article Type:
Review Article
Collections:
Bone and Mineral Metabolism
DOI:
https://doi.org/10.1530/EC-23-0305
Volume/Issue:
Volume 12: Issue 11
Open access
Kylie D Rock Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA

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Brian Horman Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA

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Allison L Phillips Nicholas School of the Environment, Duke University, Durham, North Carolina, USA

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Susan L McRitchie NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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Scott Watson NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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Jocelin Deese-Spruill NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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Dereje Jima Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA
Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, USA

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Susan Sumner NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA

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Heather M Stapleton Nicholas School of the Environment, Duke University, Durham, North Carolina, USA

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Heather B Patisaul Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA
Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA

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function, including monoamine synthesis, can be disrupted by environmental stress, resulting in sex-specific effects on neurodevelopment and behavior. Notably, maternal inflammation has been shown to disrupt forebrain neurodevelopment via increased

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0373
Volume/Issue:
Volume 7: Issue 2
Open access
Agnieszka Adamska Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland

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Paulina Tomczuk-Bobik Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland

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Anna Beata Popławska-Kita Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland

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Katarzyna Siewko Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland

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Angelika Buczyńska Clinical Research Centre, Medical University of Bialystok, Białystok, Poland

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Piotr Szumowski Department of Nuclear Medicine, Medical University of Białystok, Białystok, Poland

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Łukasz Żukowski Department of Nuclear Medicine, Medical University of Białystok, Białystok, Poland

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Janusz Myśliwiec Department of Nuclear Medicine, Medical University of Białystok, Białystok, Poland

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Monika Zbucka-Krętowska Department of Gynecological Endocrinology and Adolescent Gynecology, Medical University of Bialystok, Białystok, Poland

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Marcin Adamski Faculty of Computer Science, Bialystok University of Technology, Białystok, Poland

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Adam Jacek Krętowski Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland
Clinical Research Centre, Medical University of Bialystok, Białystok, Poland

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oxidative stress levels ( 30 ) may cause severe oocyte damages, which may lead to an impairment of their fertilization capacity, probably caused by increased oxidative stress levels through apoptosis and DNA damage upregulations. The decreased developmental

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0187
Volume/Issue:
Volume 10: Issue 10
Open access
Hong Jiang Department of Neurosurgery, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department of Neurosurgery, Rui-Jin Lu-Wan Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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WenJie Yang Department of Radiology, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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QingFang Sun Department of Neurosurgery, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Department of Neurosurgery, Rui-Jin Lu-Wan Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Chang Liu The Clinical Hospital of Chengdu Brain Science Institute, MOE Key Lab for Neuroinformation, Center for Information in Medicine, University of Electronic Science and Technology of China, Chengdu, China
College of Information Technology and Engineering, Chengdu University, Chengdu, China
College of Computer Science, Sichuan Normal University, Chengdu, Sichuan, China

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LiuGuan Bian Department of Neurosurgery, Rui-Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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. Previous studies on hypercortisolism-related brain alterations The limbic system plays an essential role in stress-related disorders, for example major depression and posttraumatic stress disorder (PTSD). It is rich in receptors for cortisol, especially

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0385
Volume/Issue:
Volume 10: Issue 11
Open access
Selina Mäkinen Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Neeta Datta Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Yen H Nguyen Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Petro Kyrylenko Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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Markku Laakso Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland

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Heikki A Koistinen Minerva Foundation Institute for Medical Research, Helsinki, Finland
Department of Medicine, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland

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). Actrapid Insulin was from Novo Nordisk (Bagsværd, DK). 2-[1,2- 3 H]-deoxy- d -glucose and d -[ 14 C]-glucose were from Perkin Elmer. Seahorse XF Glycolysis Stress Test and Mito Stress Test kits, and XF Assay media were from Agilent Technologies Inc. The

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0444
Volume/Issue:
Volume 9: Issue 11
Open access
Shenghe Luo College of Pharmacy, Yanbian University, Yanji, China

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Yunhui Zuo Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, China
Department of Cardiology, Yanbian University Hospital, Yanji, China

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Xiaotian Cui Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, China

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Meiping Zhang Department of Cardiology, Yanbian University Hospital, Yanji, China

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Honghua Jin Department of Pharmacy, Yanbian University Hospital, Yanji, China

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Lan Hong Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, China

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biological signals ( 43 , 44 , 45 ). However, other studies have shown that piezo 1 regulates cell response to mechanical stress by controlling Ca 2+ influx, and that piezo 1 expression increases in red blood cells and hepatic portal endothelial cells when

Article Type:
Research Article
Collections:
Cardiovascular
DOI:
https://doi.org/10.1530/EC-23-0176
Volume/Issue:
Volume 12: Issue 11
Open access
Juan Carlos Juárez-Cruz Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Miriam Daniela Zuñiga-Eulogio Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Monserrat Olea-Flores Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Eduardo Castañeda-Saucedo Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Miguel Ángel Mendoza-Catalán Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Carlos Ortuño-Pineda Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Ma Elena Moreno-Godínez Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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Sócrates Villegas-Comonfort Instituto de Fisiología Celular, Universidad Nacional Autónoma de Mexico, Mexico City, México

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Teresita Padilla-Benavides Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts, USA

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Napoleón Navarro-Tito Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Guerrero, Guerrero, México

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-phalloidin is shown in red and DNA is stained with DAPI. Arrows indicate focal adhesions. (E) Quantification and statistical analyses of fluorescent signal of pY397 and stress fiber formation from fluorescence images obtained from MDA-MB-231 and MCF7. Asterisks

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0442
Volume/Issue:
Volume 8: Issue 11
Open access
Sara Ullsten Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden

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Sara Bohman Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden

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Marie E Oskarsson Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden

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K Peter R Nilsson Department of Chemistry, Linköping University, Linköping, Sweden

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Gunilla T Westermark Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden

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Per-Ola Carlsson Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden
Department of Medical Sciences, Uppsala University, Uppsala, Sweden

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of high-functioning islets exhibited an increased sensitivity to hypoxia and cytokines leading to reduced survival upon stress ( 9 ). Also, islet lesions have been shown to be of a heterogeneous nature and the beta cell loss in type 2 diabetes (T2D

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0148
Volume/Issue:
Volume 6: Issue 7
Open access
Antonia Ertelt Equine Clinic, Free University of Berlin, Berlin, Germany

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Ann-Kristin Barton Equine Clinic, Free University of Berlin, Berlin, Germany

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Robert R Schmitz Equine Clinic, Free University of Berlin, Berlin, Germany

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Heidrun Gehlen Equine Clinic, Free University of Berlin, Berlin, Germany

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and laminitis. The horse shows distribution of fat at characteristic sites. The rear limbs are positioned forward to relieve stress from the front hooves, a condition associated with laminitis. Abdominal obesity is very common in humans, particularly

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-14-0038
Volume/Issue:
Volume 3: Issue 3
Open access