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Kristin Ottarsdottir, Anna G Nilsson, Margareta Hellgren, Ulf Lindblad and Bledar Daka

Introduction Testosterone plays a key role in the regulation of glucose and lipid metabolism in men ( 1 ) and women ( 2 ) although in different manners. Low concentrations of testosterone in men are associated with obesity ( 3 ), the metabolic

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Luca Persani, Biagio Cangiano and Marco Bonomi

symptoms due to this MHPD condition, such as menstrual disorders, decreased libido, hair loss, galactorrhea, pallor, altered lipid metabolism, visual defect, headache and others might overlap and cover the specific manifestations due to the hypothyroidism

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Magdalene K Montgomery and Nigel Turner

impairments in mitochondrial oxidative metabolism (i.e. mitochondrial dysfunction) could affect insulin sensitivity. Mitochondrial dysfunction can result from a decrease in mitochondrial biogenesis, reduced mitochondrial content and/or a decrease in the

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Raymond J Rodgers, Jodie C Avery, Vivienne M Moore, Michael J Davies, Ricardo Azziz, Elisabet Stener-Victorin, Lisa J Moran, Sarah A Robertson, Nigel K Stepto, Robert J Norman and Helena J Teede

PubMed ( https://www.ncbi.nlm.nih.gov/pubmed ) searches on the terms ‘polycystic’ OR ‘PCOS’ in diabetes journals selected from the top 20 ranked journals by impact factor in Thompsons ISI’s category of ‘Endocrinology and Metabolism’ with the word

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Devis Pascut, Sofia Tamini, Silvia Bresolin, Pablo Giraudi, Giuseppe Basso, Alessandro Minocci, Claudio Tiribelli, Graziano Grugni and Alessandro Sartorio

high prevalence of altered glucose metabolism that appears more common in obese and adult subjects ( 10 ), while the prevalence of metabolic syndrome is comparable to that reported in obese controls ( 11 ). Conversely, a lower risk of developing severe

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M Boering, P R van Dijk, S J J Logtenberg, K H Groenier, B H R Wolffenbuttel, R O B Gans, N Kleefstra and H J G Bilo

insulin-like growth factor binding protein 1 in vivo . Journal of Clinical Endocrinology and Metabolism 1995 80 3227 – 3232 . ( doi:10.1210/jcem.80.11.7593430 ) 2 Rosner W Hryb DJ Khan MS Nakhla AM Romas NA. Sex hormone

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Bruno Donadille, Muriel Houang, Irène Netchine, Jean-Pierre Siffroi and Sophie Christin-Maitre

in eleven patients from seven new families and comparison of the functional properties of twenty-five mutant enzymes . Journal of Clinical Endocrinology and Metabolism 1999 84 4410 – 4425 . ( https://doi.org/10.1210/jcem.84.12.6288 ) 6 Kulle

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Lianghui You, Yan Wang, Yao Gao, Xingyun Wang, Xianwei Cui, Yanyan Zhang, Lingxia Pang, Chenbo Ji, Xirong Guo and Xia Chi

demonstrated that the activation of thermogenesis in fat could produce a healthier metabolic phenotype with traits such as whole-body energy metabolism, improved glucose homeostasis, and weight loss ( 2 , 3 ). Moreover, functional BAT was discovered in adult

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Kennett Sprogøe, Eva Mortensen, David B Karpf and Jonathan A Leff

critical for a wide variety of bodily functions, including adiposity regulation, glucose control, lipid metabolism, and cognition ( 1 , 2 , 3 ). These effects are mediated both directly by GH and indirectly by insulin-like growth factor (IGF-1). In target

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Mirjana Kocova, Vesna Janevska and Violeta Anastasovska

hyperplasia due to 21-hydroxylase deficiency . Annals of Pediatric Endocrinology and Metabolism 2016 21 1 – 6 . ( https://doi.org/10.6065/apem.2016.21.1.1 ) 10.6065/apem.2016.21.1.1 2 White PC Speiser PW . Congenital adrenal hyperplasia due to 21