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Piera Rizzolo Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy

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Valentina Silvestri Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy

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Virginia Valentini Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy

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Veronica Zelli Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy

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Agostino Bucalo Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy

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Ines Zanna Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy

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Simonetta Bianchi Division of Pathological Anatomy, Department of Sciences of Health, University of Florence, Florence, Italy

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Maria Grazia Tibiletti Department of Pathology, ASST Settelaghi and Centro di Ricerca per lo Studio dei Tumori Eredo-Familiari, Università dell’Insubria, Varese, Italy

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Antonio Russo Section of Medical Oncology, Department of Surgical and Oncological and Oral Sciences, University of Palermo, Palermo, Italy

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Liliana Varesco IRCCS Ospedale Policlinico San Martino, Genoa, Italy

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Gianluca Tedaldi Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy

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Bernardo Bonanni Division of Cancer Prevention and Genetics IEO, European Institute of Oncology IRCCS, Milan, Italy

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Jacopo Azzollini Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy

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Siranoush Manoukian Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy

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Anna Coppa Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy

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Giuseppe Giannini Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy

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Laura Cortesi Department of Oncology and Haematology, University of Modena and Reggio Emilia, Modena, Italy

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Alessandra Viel Unit of Functional Onco-Genomics and Genetics, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano, Italy

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Marco Montagna Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV – IRCCS, Padua, Italy

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Paolo Peterlongo Genome Diagnostics Program, IFOM – The FIRC Institute of Molecular Oncology, Milan, Italy

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Paolo Radice Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Research, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy

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Domenico Palli Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy

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Laura Ottini Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy

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women has been reported in some populations ( 18 , 19 , 20 ); however, more recent meta-analyses showed that there is no overall effect on FBC risk ( 21 , 22 , 23 ). In line with these meta-analysis studies, our study provides no evidence that CYP1B

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0225
Volume/Issue:
Volume 8: Issue 8
Open access
Meghnaa Hebbar College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom

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Halimah Khalil College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom

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Nawal Zia College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom

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Jameela Sheikh College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom

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Eka Melson University of Leicester, Leicester, United Kingdom

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Meri Davitadze Clinic NeoLab, Tbilisi, Georgia

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Helena Gleeson Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom

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Tejal Lathia Apollo Hospitals, Mumbai, India

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Chitra Selvan Department of Endocrinology, M S Ramaiah Medical College, Bengaluru, India

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Punith Kempegowda Clinic NeoLab, Tbilisi, Georgia
Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom

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PCOS SEva Working Group
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PCOS SEva Working Group

services. This is another area of unmet needs, and clinicians need resources and services to signpost patients to evidence-based information to standardise advice and information dissemination. Although we did not find a significant difference across

Article Type:
Research Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-23-0179
Volume/Issue:
Volume 12: Issue 11
Open access
Mieke Van Hemelrijck
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Thurkaa Shanmugalingam
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Cecilia Bosco
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Wahyu Wulaningsih
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Sabine Rohrmann Cancer Epidemiology Group, Division of Chronic Disease Epidemiology, Division of Cancer Studies, King's College London, London, UK

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channels, which opens calcium stores (26, 27) . All this evidence indicates a complex interplay between IGF1 and calcium homeostasis as well as its regulators. However, no study to date has investigated the association between circulating levels of markers

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0039
Volume/Issue:
Volume 4: Issue 3
Open access
Tingting Xia Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Hongru Sun Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Hao Huang Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Haoran Bi Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Rui Pu Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Lei Zhang Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Yuanyuan Zhang Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Ying Liu Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Jing Xu Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Justina Ucheojor Onwuka Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Yupeng Liu Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Binbin Cui Department of Colorectal Surgery, The Third Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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Yashuang Zhao Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China

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accumulating evidence suggests that sex hormones are relevant to its development ( 3 ). There is an observational phenomenon and clinical evidence suggesting that men tend to have a much higher risk of CRC than women of the same age ( 4 ). As one of the most

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0122
Volume/Issue:
Volume 8: Issue 7
Open access
Jordyn Silverstein Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

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Wesley Kidder Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA

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Susan Fisher Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California, USA

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Thomas A Hope Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA

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Samantha Maisel Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

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Dianna Ng Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Department of Pathology, University of California, San Francisco, California, USA

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Jessica Van Ziffle Department of Pathology, University of California, San Francisco, California, USA

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Chloe E Atreya Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA

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Katherine Van Loon Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA

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pelvic sidewall, with direct invasion into the fundus of the uterus and fistulization into the endometrial canal ( Fig. 2 ). A staging PET/CT demonstrated no evidence of metastatic disease; however, peritoneal carcinomatosis was discovered during a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0063
Volume/Issue:
Volume 8: Issue 8
Open access
M P Schuijt Department of Laboratory Medicine, Slingeland Hospital, Doetinchem, The Netherlands
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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C G J Sweep Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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R van der Steen Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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A J Olthaar Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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N M M L Stikkelbroeck Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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H A Ross Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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A E van Herwaarden Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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–4 times less than testosterone) ( 2 , 13 , 15 , 16 ). Recently, evidence is found for differential binding of androgens and estrogens to SHBG ( 16 ) and dynamic regulation of the homodimeric SHBG-binding sites ( 2 , 17 , 18 ). In their review Goldman

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Research Article
DOI:
https://doi.org/10.1530/EC-19-0110
Volume/Issue:
Volume 8: Issue 6
Open access
Shane M Regnier Committee on Molecular Metabolism and Nutrition, Chicago, Illinois, USA
Pritzker School of Medicine, Chicago, Illinois, USA
University of Chicago, Chicago, Illinois, USA

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Andrew G Kirkley University of Chicago, Chicago, Illinois, USA
Committee on Molecular Pathogenesis and Molecular Medicine, Chicago, Illinois, USA

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Daniel Ruiz Committee on Molecular Metabolism and Nutrition, Chicago, Illinois, USA
University of Chicago, Chicago, Illinois, USA

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Wakanene Kamau University of Chicago, Chicago, Illinois, USA

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Qian Wu Wadsworth Center, New York Department of Health, Albany, New York, USA

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Kurunthachalam Kannan Wadsworth Center, New York Department of Health, Albany, New York, USA

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Robert M Sargis Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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metabolic parameters, including weight gain, adiposity and glucose tolerance. Evidence that diet composition modulates the metabolic consequences of pesticide residues suggests that Environmental Protection Agency tolerance limits may need modification based

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0320
Volume/Issue:
Volume 7: Issue 1
Open access
Zhenyu Liu Department of Clinical Medicine, Beijing Luhe Hospital, Capital Medical University, Tongzhou District, Beijing, China

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Huixi Kong Department of Clinical Medicine, Beijing Shijitan Hospital, Capital Medical University, Haidian District, Beijing, China

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Baoyu Zhang Center for Endocrine Metabolism and Immune Diseases, Beijing Luhe Hospital, Capital Medical University, Tongzhou District, Beijing, China

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-line therapies worldwide ( 24 , 67 ). A study ( 70 ) ( n  = 29 patients with T2DM) with gliclazide reported no change in SUA levels. Similar results have been reported in another study ( 71 ). At present, the mechanism is unclear, and there is no evidence

Article Type:
Review Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-24-0070
Volume/Issue:
Volume 13: Issue 6
Open access
Ping Gu Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

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Yuege Lin Department of Pathology, Nanjing Medical University, Nanjing, China

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Qi Wan Department of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

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Dongming Su Department of Pathology, Nanjing Medical University, Nanjing, China

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Qun Shu Department of Obstetrics, Shanghai First Maternity and Infant Health Hospital, School of Medicine, Tongji University, Shanghai, China

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). Recent reports have shown that oxytocin also contributes to maternal and sexual behaviors, bone formation, and metabolism ( 6 ). Strong evidence now also supports a relationship between oxytocin and diabetes; for example, Kujath et al. found lower

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0043
Volume/Issue:
Volume 10: Issue 7
Open access
Małgorzata Więcek Department of Pediatrics and Pediatric Endocrinology, Faculty of Medical Sciences, Medical University of Silesia, Katowice, Poland

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Jakub Gawlik Student Scientific Society at the Department of Pathophysiology, Jagiellonian University Medical College, Krakow, Poland

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Zuzanna Nowak Student Scientific Society at the Department of Pathophysiology, Jagiellonian University Medical College, Krakow, Poland

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Aneta Gawlik Department of Pediatrics and Pediatric Endocrinology, Faculty of Medical Sciences, Medical University of Silesia, Katowice, Poland

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, with the chance of successfully preserving the reproductive potential. More evidence is thus needed to properly assess those odds and introduce FP in patients with TS into the standard practice. Declaration of interest The authors declare that

Article Type:
Review Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-22-0344
Volume/Issue:
Volume 11: Issue 12
Open access