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Wren Laboratories, Yale University School of Medicine, 35 NE Industrial Road, Branford, Connecticut, USA
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results derived from the assays of various types, including molecular pathology assays, e.g. breast cancer arrays (Mammaprint), fluorescent in situ hybridization assays, and non-nucleic acid-based assays (27) . Algorithmic analyses, using the results of
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parenteral bisphosphonates has been a common practice since the late 1990s when results from two studies indicated that pamidronate might delay SREs in patients with breast cancer and multiple myeloma (19, 20) , bisphosphonates have not been universally
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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association with PTC, as reported in the literature (5, 6, 7, 8) . For PTTG1 , four different SNPs have been considered in previous studies. Brendle et al . (19) investigated rs1862391, rs1862392, and rs2961952 in breast cancer, whereas Löfgren et al
Department of Epidemiology St. Luke’s International University Graduate School of Public Health, Tokyo, Japan
Fujita Health University Toyoake, Japan
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Department of Epidemiology St. Luke’s International University Graduate School of Public Health, Tokyo, Japan
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cancer 68 18.1 Lung cancer 40 10.6 Colorectal cancer 38 10.1 Esophagus cancer 30 8 Breast cancer 21 5.6 Bladder and ureteral cancer 18 4.8 Liver cancer 14 3.7 Others 14 3
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). Some studies have also reported an increased risk of malignancies, including hematopoietic, breast, skin, thyroid, and urinary tract carcinoma ( 5 , 6 , 7 ). Previous studies have reported 15–75% of patients with PHPT have concomitant thyroid nodules
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, which is an enzyme that catalyzes Gln synthesis from glutamate (Glu) and NH4+. The presence or absence of GS expression is an important survival factor after exogenous Gln depletion. Therefore, cancers such as luminal breast cancer ( 11 ), MET
Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultad de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Tolima, Colombia
Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Caldas, Colombia
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Hospital Pablo Tobón Uribe, Medellín, Antioquia, Colombia
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Dinamica IPS, Medellín, Antioquia, Colombia
University of California Davis Comprehensive Cancer Center, Sacramento, California, USA
Fundación de Genética y Genómica, Medellín, Antioquia, Colombia
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D Huntsman S Li M John EM Torres-Mejia G Kushi L Ding YC Weitzel J , et al . Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas . Breast Cancer Research 2019 3 . ( https://doi.org/10
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Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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reason to believe that SHBG has its own biological effect on a cellular level. Studies in breast cancer cells exposed to estrogen have observed that SHBG, via intracellular cross talk, interferes with the pro-cancerous estrogen effect ( 32 , 33
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
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Department of Pathology, University of California, San Francisco, California, USA
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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ER-positive and PR-positive breast cancer was used as a positive control. For ERβ IHC, a tonsil with reactive lymphoid hyperplasia was used as a positive control. The slides were deparaffinized in Clear-Rite™ 3 (xylene substitute) and hydrated in
Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland
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Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
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good prognosis, for example in oral squamous cell carcinoma, triple-negative breast cancer and non-small-cell lung cancer (NSCLC) ( 8 , 9 , 10 ). Among other inflammatory cells, CD8 + T cells express membrane receptor programmed death protein 1 (PD-1