Irvin M Modlin
Irvin M Modlin
Wren Laboratories, Yale University School of Medicine, 35 NE Industrial Road, Branford, Connecticut, USA
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Harry Aslanian
Harry Aslanian
Wren Laboratories, Yale University School of Medicine, 35 NE Industrial Road, Branford, Connecticut, USA
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Lisa Bodei
Lisa Bodei
Wren Laboratories, Yale University School of Medicine, 35 NE Industrial Road, Branford, Connecticut, USA
Wren Laboratories, Yale University School of Medicine, 35 NE Industrial Road, Branford, Connecticut, USA
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Wren Laboratories, Yale University School of Medicine, 35 NE Industrial Road, Branford, Connecticut, USA
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Ignat Drozdov
Ignat Drozdov
Wren Laboratories, Yale University School of Medicine, 35 NE Industrial Road, Branford, Connecticut, USA
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Mark Kidd
Mark Kidd
Wren Laboratories, Yale University School of Medicine, 35 NE Industrial Road, Branford, Connecticut, USA
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results derived from the assays of various types, including molecular pathology assays, e.g. breast cancer arrays (Mammaprint), fluorescent in situ hybridization assays, and non-nucleic acid-based assays (27) . Algorithmic analyses, using the results of
Katherine Van Loon
Katherine Van Loon
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Li Zhang
Li Zhang
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Jennifer Keiser
Jennifer Keiser
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Cendy Carrasco
Cendy Carrasco
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Katherine Glass
Katherine Glass
The UCSF Helen Diller Family Comprehensive Cancer Center, The Ohio State University Comprehensive Cancer Center, National Comprehensive Cancer Network, University of California, San Francisco, 1600 Divisadero Street, UCSF Box 1770, San Francisco, California 94143, USA
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Maria-Teresa Ramirez
Maria-Teresa Ramirez
The UCSF Helen Diller Family Comprehensive Cancer Center, The Ohio State University Comprehensive Cancer Center, National Comprehensive Cancer Network, University of California, San Francisco, 1600 Divisadero Street, UCSF Box 1770, San Francisco, California 94143, USA
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Sarah Bobiak
Sarah Bobiak
The UCSF Helen Diller Family Comprehensive Cancer Center, The Ohio State University Comprehensive Cancer Center, National Comprehensive Cancer Network, University of California, San Francisco, 1600 Divisadero Street, UCSF Box 1770, San Francisco, California 94143, USA
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Eric K Nakakura
Eric K Nakakura
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Alan P Venook
Alan P Venook
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Manisha H Shah
Manisha H Shah
The UCSF Helen Diller Family Comprehensive Cancer Center, The Ohio State University Comprehensive Cancer Center, National Comprehensive Cancer Network, University of California, San Francisco, 1600 Divisadero Street, UCSF Box 1770, San Francisco, California 94143, USA
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Emily K Bergsland
Emily K Bergsland
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parenteral bisphosphonates has been a common practice since the late 1990s when results from two studies indicated that pamidronate might delay SREs in patients with breast cancer and multiple myeloma (19, 20) , bisphosphonates have not been universally
Marco Marino
Marco Marino
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Valentina Cirello
Valentina Cirello
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Valentina Gnarini
Valentina Gnarini
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Carla Colombo
Carla Colombo
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Elisa Pignatti
Elisa Pignatti
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Livio Casarini
Livio Casarini
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Chiara Diazzi
Chiara Diazzi
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Vincenzo Rochira
Vincenzo Rochira
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Katia Cioni
Katia Cioni
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Bruno Madeo
Bruno Madeo
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Cesare Carani
Cesare Carani
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Manuela Simoni
Manuela Simoni
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Laura Fugazzola
Laura Fugazzola
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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Unit and Chair of Endocrinology and Metabolism, Center for Genomic Research, Department of Clinical Sciences and Community Health, Endocrine Unit, Azienda USL of Modena, NOCSAE, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Pietro Giardini 1355, 41126 Modena, Italy
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association with PTC, as reported in the literature (5, 6, 7, 8) . For PTTG1 , four different SNPs have been considered in previous studies. Brendle et al . (19) investigated rs1862391, rs1862392, and rs2961952 in breast cancer, whereas Löfgren et al
Daiki Kobayashi
Daiki Kobayashi
Division of General Internal Medicine Department of Medicine, St. Luke’s International Hospital, Tokyo, Japan
Department of Epidemiology St. Luke’s International University Graduate School of Public Health, Tokyo, Japan
Fujita Health University Toyoake, Japan
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Department of Epidemiology St. Luke’s International University Graduate School of Public Health, Tokyo, Japan
Fujita Health University Toyoake, Japan
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Nagato Kuriyama
Nagato Kuriyama
Department of Epidemiology for Community Health and Medicine Kyoto Prefectural University of Medicine, Kyoto, Japan
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Keita Hirano
Keita Hirano
Department of Nephrology Kyoto University Graduate School of Medicine, Kyoto, Japan
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Osamu Takahashi
Osamu Takahashi
Division of General Internal Medicine Department of Medicine, St. Luke’s International Hospital, Tokyo, Japan
Department of Epidemiology St. Luke’s International University Graduate School of Public Health, Tokyo, Japan
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Department of Epidemiology St. Luke’s International University Graduate School of Public Health, Tokyo, Japan
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Hiroshi Noto
Hiroshi Noto
Department of Endocrinology St. Luke’s International Hospital, Tokyo, Japan
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cancer 68 18.1 Lung cancer 40 10.6 Colorectal cancer 38 10.1 Esophagus cancer 30 8 Breast cancer 21 5.6 Bladder and ureteral cancer 18 4.8 Liver cancer 14 3.7 Others 14 3
Luchuan Li
Luchuan Li
Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China
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Baoyuan Li
Baoyuan Li
Department of Thyroid Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China
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Bin Lv
Bin Lv
Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China
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Weili Liang
Weili Liang
Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China
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Binbin Zhang
Binbin Zhang
Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China
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Qingdong Zeng
Qingdong Zeng
Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China
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Andrew G Turner
Andrew G Turner
Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia
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Lei Sheng
Lei Sheng
Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China
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). Some studies have also reported an increased risk of malignancies, including hematopoietic, breast, skin, thyroid, and urinary tract carcinoma ( 5 , 6 , 7 ). Previous studies have reported 15–75% of patients with PHPT have concomitant thyroid nodules
Jintao Hu
Jintao Hu
Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China
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Qingbo Chen
Qingbo Chen
Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China
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Xiao Ding
Xiao Ding
Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China
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Xin Zheng
Xin Zheng
Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China
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Xuefeng Tang
Xuefeng Tang
Department of Pathology, Xinqiao Hospital, The Army Medical University, Chongqing, China
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Song Li
Song Li
Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China
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Hui Yang
Hui Yang
Department of Neurosurgery, Xinqiao Hospital, The Army Medical University, Chongqing, China
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, which is an enzyme that catalyzes Gln synthesis from glutamate (Glu) and NH4+. The presence or absence of GS expression is an important survival factor after exogenous Gln depletion. Therefore, cancers such as luminal breast cancer ( 11 ), MET
Ana P Estrada-Flórez
Ana P Estrada-Flórez
Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, California, USA
Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultad de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Tolima, Colombia
Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Caldas, Colombia
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Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultad de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Tolima, Colombia
Facultad de Ciencias para la Salud, Universidad de Caldas, Manizales, Caldas, Colombia
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Mabel E Bohórquez
Mabel E Bohórquez
Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultad de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Tolima, Colombia
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Alejandro Vélez
Alejandro Vélez
Dinamica IPS, Medellín, Antioquia, Colombia
Hospital Pablo Tobón Uribe, Medellín, Antioquia, Colombia
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Hospital Pablo Tobón Uribe, Medellín, Antioquia, Colombia
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Carlos S Duque
Carlos S Duque
Hospital Pablo Tobón Uribe, Medellín, Antioquia, Colombia
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Jorge H Donado
Jorge H Donado
Hospital Pablo Tobón Uribe, Medellín, Antioquia, Colombia
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Gilbert Mateus
Gilbert Mateus
Hospital Federico Lleras Acosta, Ibagué, Tolima, Colombia
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Cesar Panqueba-Tarazona
Cesar Panqueba-Tarazona
Universidad Surcolombiana, Neiva, Huila, Colombia
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Guadalupe Polanco-Echeverry
Guadalupe Polanco-Echeverry
Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, California, USA
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Ruta Sahasrabudhe
Ruta Sahasrabudhe
Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, California, USA
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Magdalena Echeverry
Magdalena Echeverry
Grupo de Citogenética, Filogenia y Evolución de Poblaciones, Facultad de Ciencias y Facultad de Ciencias de la Salud, Universidad del Tolima, Ibagué, Tolima, Colombia
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Luis G Carvajal-Carmona
Luis G Carvajal-Carmona
Genome Center and Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, California, USA
Dinamica IPS, Medellín, Antioquia, Colombia
University of California Davis Comprehensive Cancer Center, Sacramento, California, USA
Fundación de Genética y Genómica, Medellín, Antioquia, Colombia
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Dinamica IPS, Medellín, Antioquia, Colombia
University of California Davis Comprehensive Cancer Center, Sacramento, California, USA
Fundación de Genética y Genómica, Medellín, Antioquia, Colombia
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D Huntsman S Li M John EM Torres-Mejia G Kushi L Ding YC Weitzel J , et al . Identification of novel common breast cancer risk variants at the 6q25 locus among Latinas . Breast Cancer Research 2019 3 . ( https://doi.org/10
Kristin Ottarsdottir
Kristin Ottarsdottir
Primary Health Care, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Margareta Hellgren
Margareta Hellgren
Primary Health Care, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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David Bock
David Bock
Biostatistics, School of Public Health and Community Medicine, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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Anna G Nilsson
Anna G Nilsson
Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Bledar Daka
Bledar Daka
Primary Health Care, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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reason to believe that SHBG has its own biological effect on a cellular level. Studies in breast cancer cells exposed to estrogen have observed that SHBG, via intracellular cross talk, interferes with the pro-cancerous estrogen effect ( 32 , 33
Jordyn Silverstein
Jordyn Silverstein
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
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Wesley Kidder
Wesley Kidder
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Susan Fisher
Susan Fisher
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California, USA
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Thomas A Hope
Thomas A Hope
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
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Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
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Samantha Maisel
Samantha Maisel
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
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Dianna Ng
Dianna Ng
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Department of Pathology, University of California, San Francisco, California, USA
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Department of Pathology, University of California, San Francisco, California, USA
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Jessica Van Ziffle
Jessica Van Ziffle
Department of Pathology, University of California, San Francisco, California, USA
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Chloe E Atreya
Chloe E Atreya
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Katherine Van Loon
Katherine Van Loon
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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ER-positive and PR-positive breast cancer was used as a positive control. For ERβ IHC, a tonsil with reactive lymphoid hyperplasia was used as a positive control. The slides were deparaffinized in Clear-Rite™ 3 (xylene substitute) and hydrated in
Tiina Vesterinen
Tiina Vesterinen
HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland
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Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland
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Teijo Kuopio
Teijo Kuopio
Department of Biological and Environmental Science, University of Jyväskylä and Department of Pathology, Central Finland Health Care District, Jyväskylä, Finland
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Maarit Ahtiainen
Maarit Ahtiainen
Department of Education and Research, Central Finland Central Hospital, Jyväskylä, Finland
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Aija Knuuttila
Aija Knuuttila
Department of Pulmonary Medicine, Heart and Lung Center, and Cancer Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Harri Mustonen
Harri Mustonen
Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Kaisa Salmenkivi
Kaisa Salmenkivi
HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Johanna Arola
Johanna Arola
HUSLAB, Department of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Caj Haglund
Caj Haglund
Department of Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
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Translational Cancer Medicine Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
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good prognosis, for example in oral squamous cell carcinoma, triple-negative breast cancer and non-small-cell lung cancer (NSCLC) ( 8 , 9 , 10 ). Among other inflammatory cells, CD8 + T cells express membrane receptor programmed death protein 1 (PD-1
