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the thyroid gland is under strict regulatory control in the production and secretion of its hormones, there are conditions that can induce an imbalance of circulating TH levels. Graves’ disease, TSH-secreting adenomas and toxic multinodular goiter are
Department of Diabetes and Endocrinology, Skåne University Hospital, Malmö, Sweden
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Department of Clinical Sciences, Lund University, Malmö, Sweden
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Department of Plastic Surgery, Skåne University Hospital, Malmö, Sweden
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Department of Diabetes and Endocrinology, Skåne University Hospital, Malmö, Sweden
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Department of Diabetes and Endocrinology, Skåne University Hospital, Malmö, Sweden
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Introduction Autoimmune thyroid disease is a prerequisite for the development of Graves’ ophthalmopathy (GO), and both thyroid and orbital tissues are infiltrated by immunocompetent cells. The thyroid-stimulating hormone receptor (TSHR) acts
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. None of the patients had a history of thyroid diseases. Methods Data on clinical findings, laboratory findings, imaging findings, treatment and outcome were obtained. All CD patients (microadenomas: 88/102, macroadenomas: 14/102) underwent
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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Department of Paediatric Endocrinology, Astrid Lindgren Children Hospital, Karolinska University Hospital, Stockholm, Sweden
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Department of Pediatric Endocrinology, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris, Le Kremlin Bicêtre, France
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three larger groups of DSD, namely TS, KS and CAH. These reports have indicated increased risks of congenital abnormalities in TS, cardiometabolic risk factors and diseases mostly related to treatment, autoimmune disorders, tumors and psychiatric
Endocrinology & Diabetes, Salford Royal NHS Foundation Trust, Salford, UK
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Endocrinology & Diabetes, Salford Royal NHS Foundation Trust, Salford, UK
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CEDM Centre of Endocrinology, Diabetes & Metabolism, Limassol, Cyprus
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Endocrinology & Diabetes, Salford Royal NHS Foundation Trust, Salford, UK
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Endocrinology & Diabetes, Salford Royal NHS Foundation Trust, Salford, UK
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Introduction Thyrotoxicosis, a clinical state resulting from inappropriately high thyroid hormone levels, is a condition with multiple aetiologies ( 1 ). It is commonly caused by Graves’ disease (GD), toxic multinodular goitre (TMNG) or toxic
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. 27741547 13 Strieder TG Prummel MF Tijssen JG Endert E Wiersinga WM. Risk factors for and prevalence of thyroid disorders in a cross‐sectional study among healthy female relatives of patients with autoimmune thyroid disease . Clinical Endocrinology
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article) shows the pathways that are significantly enriched by 545 upregulated DEGs in high VDR group, using DAVID. Cellular interaction, autoimmune thyroid disease, immune receptor-related signal pathways, cancer-related chemokine signaling and the JAK
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studies have provided more information on the causes of CH ( 2 , 4 , 5 , 6 ). To date, more than 20 disease-causing genes have been reported to be linked with the pathogenesis of CH ( 1 , 7 , 8 , 9 , 10 ). TD is defined as abnormal thyroid gland
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the diagnostic accuracy of both USS and MIBI (USS: 71.4% sensitivity, 78.9% specificity; MIBI: 35.7% sensitivity, 42.1% specificity), possibly due to FN results (predominantly in autoimmune thyroid disease) and false-positive results (mainly in nodular
Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
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irradiation Drugs (e.g., rexinoids or mitotane) Injuries Head trauma Traumatic delivery Vascular accidents Pituitary infarction Sheenan syndrome Subarachnoid hemorrhage Autoimmune disease