Arno Téblick
Arno Téblick
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Lies Langouche
Lies Langouche
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Greet Van den Berghe
Greet Van den Berghe
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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para-/autocrine hormone insulin-like growth factor-I (IGF-I), is named for one of its main functions: mediating linear bone and organ growth. Whereas adequate nutritional intake and adequate sex hormone levels are the main growth promoters during
Mirjana Doknic
Mirjana Doknic
Neuroendocrine Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Belgrade, Serbia
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Marko Stojanovic
Marko Stojanovic
Neuroendocrine Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Belgrade, Serbia
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Ivan Soldatovic
Ivan Soldatovic
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Institute of Medical Statistics and Informatics, Belgrade, Serbia
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Institute of Medical Statistics and Informatics, Belgrade, Serbia
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Tatjana Milenkovic
Tatjana Milenkovic
Mother and Child Health Care Institute of Serbia ‘Dr Vukan Cupic’, Belgrade, Serbia
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Vera Zdravkovic
Vera Zdravkovic
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
University Children’s Clinic, Belgrade, Serbia
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University Children’s Clinic, Belgrade, Serbia
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Maja Jesic
Maja Jesic
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
University Children’s Clinic, Belgrade, Serbia
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University Children’s Clinic, Belgrade, Serbia
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Sladjana Todorovic
Sladjana Todorovic
Mother and Child Health Care Institute of Serbia ‘Dr Vukan Cupic’, Belgrade, Serbia
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Katarina Mitrovic
Katarina Mitrovic
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Mother and Child Health Care Institute of Serbia ‘Dr Vukan Cupic’, Belgrade, Serbia
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Mother and Child Health Care Institute of Serbia ‘Dr Vukan Cupic’, Belgrade, Serbia
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Rade Vukovic
Rade Vukovic
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Mother and Child Health Care Institute of Serbia ‘Dr Vukan Cupic’, Belgrade, Serbia
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Mother and Child Health Care Institute of Serbia ‘Dr Vukan Cupic’, Belgrade, Serbia
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Dragana Miljic
Dragana Miljic
Neuroendocrine Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Belgrade, Serbia
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Dragan Savic
Dragan Savic
Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
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Mihajlo Milicevic
Mihajlo Milicevic
Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
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Aleksandar Stanimirovic
Aleksandar Stanimirovic
Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
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Vojislav Bogosavljevic
Vojislav Bogosavljevic
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
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Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
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Sandra Pekic
Sandra Pekic
Neuroendocrine Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Belgrade, Serbia
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Emilija Manojlovic-Gacic
Emilija Manojlovic-Gacic
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Institute of Pathology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Institute of Pathology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Aleksandar Djukic
Aleksandar Djukic
Department of Pathophysiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia
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Danica Grujicic
Danica Grujicic
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
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Clinic for Neurosurgery, University Clinical Center of Serbia, Belgrade, Serbia
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Milan Petakov
Milan Petakov
Neuroendocrine Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, University Clinical Center of Serbia, Belgrade, Serbia
Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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Faculty of Medicine, University of Belgrade, Belgrade, Serbia
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.0%). Recovery of GH/IGF-I axis was confirmed in 28.2% of all patients in this cohort (40/142). The prevalence of GH/IGF-I axis recovery was greatest in the IDOP subgroup (31/43; 72%). TUMC and CONG groups demonstrated a significantly lower prevalence of
Anastasia P Athanasoulia-Kaspar
Anastasia P Athanasoulia-Kaspar
Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
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Matthias K Auer
Matthias K Auer
Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany
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Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany
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Günter K Stalla
Günter K Stalla
Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
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Mira Jakovcevski
Mira Jakovcevski
Department of Stress Neurobiology and Neurogenetics, Max Planck Institute of Psychiatry, Munich, Germany
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.pone.0120185 15 Matsumoto R Fukuoka H Iguchi G Odake Y Yoshida K Bando H Suda K Nishizawa H Takahashi M Yamada S , et al . Accelerated telomere shortening in acromegaly; IGF-I induces telomere shortening and cellular senescence . PLoS ONE 2015 10 e
Anna Kistner
Anna Kistner
Women and Child Health, Karolinska Institutet, SE-171 76 Stockholm, Sweden
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Mireille Vanpée
Mireille Vanpée
Women and Child Health, Karolinska Institutet, SE-171 76 Stockholm, Sweden
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Kerstin Hall
Kerstin Hall
Women and Child Health, Karolinska Institutet, SE-171 76 Stockholm, Sweden
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klinische Biochemie 1975 13 101 – 107 . 28 Bang P Eriksson U Sara V Wivall IL Hall K . Comparison of acid ethanol extraction and acid gel filtration prior to IGF-I and IGF-II radioimmunoassays
Lára Ósk Eggertsdóttir Claessen
Lára Ósk Eggertsdóttir Claessen
Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland
Department of Emergency Medicine, Landspitali – The National University Hospital of Iceland, Reykjavik, Iceland
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Department of Emergency Medicine, Landspitali – The National University Hospital of Iceland, Reykjavik, Iceland
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Hafrún Kristjánsdóttir
Hafrún Kristjánsdóttir
Physical Activity, Physical Education, Sport, and Health (PAPESH) Research Centre, Sports Science Department, School of Social Sciences, Reykjavik University, Reykjavik, Iceland
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María Kristín Jónsdóttir
María Kristín Jónsdóttir
Mental Health Services, Landspitali – The National University Hospital of Iceland, Reykjavik, Iceland
Department of Psychology, School of Social Sciences, Reykjavik University, Reykjavik, Iceland
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Department of Psychology, School of Social Sciences, Reykjavik University, Reykjavik, Iceland
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Sigrún Helga Lund
Sigrún Helga Lund
deCODE Genetics, Inc/Amgen Inc., Reykjavik, Iceland
School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland
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School of Engineering and Natural Sciences, University of Iceland, Reykjavik, Iceland
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Ingunn Unnsteinsdóttir Kristensen
Ingunn Unnsteinsdóttir Kristensen
Department of Psychology, School of Social Sciences, Reykjavik University, Reykjavik, Iceland
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Helga Ágústa Sigurjónsdóttir
Helga Ágústa Sigurjónsdóttir
Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland
Department of Medicine, Landspitali – The National University Hospital of Iceland, Reykjavik, Iceland
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Department of Medicine, Landspitali – The National University Hospital of Iceland, Reykjavik, Iceland
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:10 h): 133–537 nmol/L, afternoon (16:08 h): 68.2–327 nmol/L Serum +2–8°C IGF1 IGF-I Siemens Immulite 2000 6.3 3.1 2.5 15–1000 μg/L Manufacturer’s age-dependent reference range a Serum +2–8°C or −20°C ACTH ACTH
Johan Verhelst
Johan Verhelst
Department of Endocrinology, ZNA Middelheim Hospital, Antwerp, Belgium
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Anders F Mattsson
Anders F Mattsson
Pfizer Endocrine Care, Pfizer Health AB, Sollentuna, Sweden
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Cecilia Camacho-Hübner
Cecilia Camacho-Hübner
Pfizer Endocrine Care, Pfizer, Inc., New York, New York, USA
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Anton Luger
Anton Luger
Division of Endocrinology and Metabolism, Medical University and General Hospital, Vienna, Austria
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Roger Abs
Roger Abs
Antwerp Centre for Endocrinology, Antwerp, Belgium
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performed in a central laboratory according to well-defined methods ( 3 ). Serum IGF-I was measured centrally using methods detailed in previous KIMS publications ( 3 ). Quality of life was assessed by the QoL-AGHDA questionnaire, which scores ranges from 0
Emily Warmington
Emily Warmington
Institute of Metabolism and System Research, University of Birmingham, Birmingham, UK
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Gabrielle Smith
Gabrielle Smith
Institute of Metabolism and System Research, University of Birmingham, Birmingham, UK
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Vasileios Chortis
Vasileios Chortis
Institute of Metabolism and System Research, University of Birmingham, Birmingham, UK
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Raimunde Liang
Raimunde Liang
Division of Endocrinology and Diabetes, University Hospital of Wuerzburg, Wuerzburg, Germany
Department of Neurosurgery, Technical University Munich (TMU), Munich, Germany
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Department of Neurosurgery, Technical University Munich (TMU), Munich, Germany
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Juliane Lippert
Juliane Lippert
Division of Endocrinology and Diabetes, University Hospital of Wuerzburg, Wuerzburg, Germany
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Sonja Steinhauer
Sonja Steinhauer
Division of Endocrinology and Diabetes, University Hospital of Wuerzburg, Wuerzburg, Germany
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Laura-Sophie Landwehr
Laura-Sophie Landwehr
Division of Endocrinology and Diabetes, University Hospital of Wuerzburg, Wuerzburg, Germany
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Constanze Hantel
Constanze Hantel
Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland
Medizinische Klinik Und Poliklinik III, University Hospital Carl Gustav Carus, Dresden, Germany
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Medizinische Klinik Und Poliklinik III, University Hospital Carl Gustav Carus, Dresden, Germany
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Katja Kiseljak-Vassiliades
Katja Kiseljak-Vassiliades
Division of Endocrinology Metabolism and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
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Margaret E Wierman
Margaret E Wierman
Division of Endocrinology Metabolism and Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
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Barbara Altieri
Barbara Altieri
Division of Endocrinology and Diabetes, University Hospital of Wuerzburg, Wuerzburg, Germany
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Paul A Foster
Paul A Foster
Institute of Metabolism and System Research, University of Birmingham, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Cristina L Ronchi
Cristina L Ronchi
Institute of Metabolism and System Research, University of Birmingham, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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was reflected with IGF2 expression, though in this case, expression was very high in CU-ACC1 (136.08-fold), while it was under-expressed in MUC-1 cells (0.17-fold). Of note, CU-ACC1 cells presented some differences compared to other cell lines, i
Vanderlan O Batista
Vanderlan O Batista
Division of Psychiatry, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Michael Kellner
Michael Kellner
Department of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf, Hamburg, Germany and Technical University of Munich, Munich, Germany
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Roberto Salvatori
Roberto Salvatori
Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Walter Lisboa
Walter Lisboa
Department of Psychology, Federal University of Sergipe, São Cristovão, Sergipe, Brazil
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André Faro
André Faro
Postgraduate Program in Psychology, Federal University of Sergipe, São Cristovão, Sergipe, Brazil
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Lucas B Santos
Lucas B Santos
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Enaldo V Melo
Enaldo V Melo
Statistics division, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Alécia A Oliveira-Santos
Alécia A Oliveira-Santos
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Carla R P Oliveira
Carla R P Oliveira
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Viviane C Campos
Viviane C Campos
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Cynthia S Barros-Oliveira
Cynthia S Barros-Oliveira
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Elenilde G Santos
Elenilde G Santos
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Nathalie O Santana
Nathalie O Santana
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Keila R Villar-Gouy
Keila R Villar-Gouy
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Ângela C Leal
Ângela C Leal
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Rivia S Amorim
Rivia S Amorim
Division of Geriatrics, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Davi A Oliveira Simões
Davi A Oliveira Simões
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Manuel H Aguiar-Oliveira
Manuel H Aguiar-Oliveira
Division of Endocrinology, Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Campos VC Oliveira-Neto LA & Salvatori R . Mechanisms in Endocrinology: the multiple facets of GHRH/GH/IGF-I. axis: lessons from lifetime, untreated, isolated GH deficiency due to a GHRH receptor gene mutation . European Journal of Endocrinology
Krzysztof C Lewandowski
Krzysztof C Lewandowski
Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, Lodz, Poland
Polish Mother’s Memorial Hospital–Research Institute, Lodz, Poland
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Polish Mother’s Memorial Hospital–Research Institute, Lodz, Poland
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Justyna Płusajska
Justyna Płusajska
Polish Mother’s Memorial Hospital–Research Institute, Lodz, Poland
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Wojciech Horzelski
Wojciech Horzelski
Faculty of Mathematics and Computer Science, University of Lodz, Lodz, Poland
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Ewa Bieniek
Ewa Bieniek
Polish Mother’s Memorial Hospital–Research Institute, Lodz, Poland
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Andrzej Lewiński
Andrzej Lewiński
Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, Lodz, Poland
Polish Mother’s Memorial Hospital–Research Institute, Lodz, Poland
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Polish Mother’s Memorial Hospital–Research Institute, Lodz, Poland
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tests (such as IGF-I, growth hormone during OGTT, 17-hydroxy-progesterone measurements after 250 µg of intravenous Synacthen, 24-h prolactin secretion profiles) were performed. All investigations were performed in the early follicular phase of either a
Kathryn L Gatford
Kathryn L Gatford
Robinson Research Institute, The University of Adelaide, Adelaide, Australia
Adelaide Medical School, The University of Adelaide, Adelaide, Australia
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Adelaide Medical School, The University of Adelaide, Adelaide, Australia
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Beverly S Muhlhausler
Beverly S Muhlhausler
FOOD plus Research Centre, School of Agriculture, Food and Wine, The University of Adelaide, Adelaide, Australia
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Lili Huang
Lili Huang
School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia
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Pamela Su-Lin Sim
Pamela Su-Lin Sim
FOOD plus Research Centre, School of Agriculture, Food and Wine, The University of Adelaide, Adelaide, Australia
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Claire T Roberts
Claire T Roberts
Robinson Research Institute, The University of Adelaide, Adelaide, Australia
Adelaide Medical School, The University of Adelaide, Adelaide, Australia
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Adelaide Medical School, The University of Adelaide, Adelaide, Australia
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Johannes D Velhuis
Johannes D Velhuis
Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota, USA
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Chen Chen
Chen Chen
School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia
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Gerrard DE Matteri RL Day BN. Effects of recombinant porcine growth hormone on placental size, fetal growth, and IGF-I and IGF-II concentrations in pigs . Journal of Animal Science 1995 73 2980 – 2985 . ( doi:10.2527/1995.73102980x
