Barbara J Boucher
Barbara J Boucher
Blizard Institute, Barts & The London school of Medicine & Dentistry, Queen Mary University of London, London, UK
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associated with obesity, immunity, the rates of many infections, cancers (e.g. breast and colorectal), and cancer mortality, with chronic disorders such as insulin resistance, metabolic syndrome (Syndrome X), type 2 diabetes (T2DM), acute cardiovascular
Masatada Watanabe
Masatada Watanabe
Laboratory of Tissue Regeneration, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo, Japan
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Shuji Ohno
Shuji Ohno
Division of Research for Pharmacy Students Education, Hoshi University, Shinagawa, Tokyo, Japan
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Hiroshi Wachi
Hiroshi Wachi
Laboratory of Tissue Regeneration, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo, Japan
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contraction of peripheral blood vessels, whereas an increase in the circulating glucocorticoid concentration suppresses the immune system. Consequently, long-term stress could make the body vulnerable to atopic dermatitis, in other words, could result in an
June Young Choi
June Young Choi
Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Korea
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Jin Wook Yi
Jin Wook Yi
Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea
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Jun Hyup Lee
Jun Hyup Lee
Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea
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Ra-Yeong Song
Ra-Yeong Song
Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea
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Hyeongwon Yu
Hyeongwon Yu
Department of Surgery, Seoul National University Bundang Hospital, Seongnam-si, Korea
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Hyungju Kwon
Hyungju Kwon
Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea
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Young Jun Chai
Young Jun Chai
Department of Surgery, Seoul National University Boramae Hospital, Seoul, Korea
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Su-jin Kim
Su-jin Kim
Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea
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Kyu Eun Lee
Kyu Eun Lee
Department of Surgery, Seoul National University Hospital and College of Medicine, Seoul, Korea
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article) shows the pathways that are significantly enriched by 545 upregulated DEGs in high VDR group, using DAVID. Cellular interaction, autoimmune thyroid disease, immune receptor-related signal pathways, cancer-related chemokine signaling and the JAK
Kusum Lata
Kusum Lata
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Pinaki Dutta
Pinaki Dutta
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Subbiah Sridhar
Subbiah Sridhar
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Minakshi Rohilla
Minakshi Rohilla
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Anand Srinivasan
Anand Srinivasan
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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G R V Prashad
G R V Prashad
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Viral N Shah
Viral N Shah
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Anil Bhansali
Anil Bhansali
Departments of Obstetrics and Gynecology, Endocrinology, Pharmacology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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effect on granulosa cells, luteal cells and oocyte maturation (8) . Euthyroid women with thyroid autoimmunity are twice as likely to experience spontaneous miscarriages (9) . This probably represents a generalised activation of the immune system, or an
Xi Zhang
Xi Zhang
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Xiurong Shen
Xiurong Shen
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Wan Zhou
Wan Zhou
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Mengyun Xu
Mengyun Xu
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Yan Xing
Yan Xing
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Jianping Weng
Jianping Weng
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Shandong Ye
Shandong Ye
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Suowen Xu
Suowen Xu
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Zhi Zhang
Zhi Zhang
Hefei National Laboratory for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Wei Wang
Wei Wang
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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chromatography with an HbA1c radiometer (Bio-Rad Laboratory Inc.). Urinary albumin was assayed using immune turbidimetry kits purchased from Northern Biotechnology Research Institute (Beijing, China). Urine albumin creatinine ratio (UACR) was calculated as the
Qi Che
Qi Che
Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China
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Xirong Xiao
Xirong Xiao
Department of Obstetrics, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China
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Jun Xu
Jun Xu
Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China
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Miao Liu
Miao Liu
Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China
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Yongning Lu
Yongning Lu
Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China
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Suying Liu
Suying Liu
Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China
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Xi Dong
Xi Dong
Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China
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tumor tissues ( 6 ). IL-6 belongs to the main member of the IL-6 cytokine family and regulates multitudinous functions related to biological metabolism and immunity ( 7 ). Abnormal IL-6 cytokine expression and its aberrant downstream signaling activation
Clara Lundetoft Clausen
Clara Lundetoft Clausen
Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark
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Trine Holm Johannsen
Trine Holm Johannsen
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Niels Erik Skakkebæk
Niels Erik Skakkebæk
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Hanne Frederiksen
Hanne Frederiksen
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Thomas Benfield
Thomas Benfield
Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Vlachogiannis NI Paraskevis D Kaltsas GA Chrousos GP , et al. Alterations in cortisol and interleukin-6 secretion in patients with COVID-19 suggestive of neuroendocrine-immune adaptations. Endocrine 2022 75 317 – 327 . ( https://doi.org/10.1007/s12020
Charlotte Höybye
Charlotte Höybye
Patient Area Endocrinology and Nephrology, Infection and Inflammation Theme, Karolinska University Hospital, Stockholm, Sweden
Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden
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Laia Faseh
Laia Faseh
Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden
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Christos Himonakos
Christos Himonakos
Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden
Department of Medicine, Karlstad Hospital, Karlstad, Sweden
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Department of Medicine, Karlstad Hospital, Karlstad, Sweden
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Tomasz Pielak
Tomasz Pielak
NUTOPI Sp. z o. o., Poznan, Poland
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Jesper Eugen-Olsen
Jesper Eugen-Olsen
Clinical Research Centre, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark
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plasminogen activator receptor (uPAR) is a membrane bound receptor mainly expressed on immune cells ( 15 , 16 ). uPAR is involved in several physiological and pathological pathways including cell signalling, cell migration, immune response, angiogenesis and
Yun Cai
Yun Cai
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Jieni Yan
Jieni Yan
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Yong Gu
Yong Gu
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Heng Chen
Heng Chen
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Yang Chen
Yang Chen
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Xinyu Xu
Xinyu Xu
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Mei Zhang
Mei Zhang
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Liping Yu
Liping Yu
Barbara Davis Center for Diabetes, University of Colorado School of Medicine, Aurora, Colorado, USA
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Xuqin Zheng
Xuqin Zheng
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Tao Yang
Tao Yang
Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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, develops through a complex interaction of genetic and environmental risk factors which result in autoimmune destruction of the specific organs involving humoral and cellular immune responses ( 1 , 2 , 4 , 8 , 9 ). Many studies have showed the prevalence
Tingting Xia
Tingting Xia
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Hongru Sun
Hongru Sun
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Hao Huang
Hao Huang
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Haoran Bi
Haoran Bi
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Rui Pu
Rui Pu
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Lei Zhang
Lei Zhang
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Yuanyuan Zhang
Yuanyuan Zhang
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Ying Liu
Ying Liu
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Jing Xu
Jing Xu
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Justina Ucheojor Onwuka
Justina Ucheojor Onwuka
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Yupeng Liu
Yupeng Liu
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Binbin Cui
Binbin Cui
Department of Colorectal Surgery, The Third Hospital of Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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Yashuang Zhao
Yashuang Zhao
Department of Epidemiology, Public Health College, Harbin Medical University, Harbin, Heilongjiang Province, People’s Republic of China
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development of CRC involves alterations not only in tumor tissues but also other organ systems, including the immune system ( 13 , 14 ). Leukocytes serve as a major component of immunology and have the advantages of easy access and detection. Analyses have
