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>100 mg/dL (5.6 mmol/L) or type 2 diabetes (defined by a random or 2 h OGTT glucose ≥200 mg/dL (11.1 mmol/L); a HbA1c ≥6.4% or the use of anti-diabetic drugs ( 20 ). The MetS score, ranging between 0 and 5, corresponds to the sum of the abnormal MetS
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fasting glucose and insulin levels were increased in FGF1−/− mice fed with an HFD ( 22 ). Wang et al . reported that serum FGF1 significantly correlated with fasting glucose, 2-h post-OGTT glucose and HOMA-β ( 8 ). In addition, HbA1c were the independent
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blood glucose, or 2 h-OGTT test ≥ 11.0 mmol/L, was taking diabetes-related drugs. BMI was calculated based on height and weight, and its formula is BMI = weight/height-squared (kg/m 2 ). Laboratory data The collection of laboratory data was
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patients. In addition to this, the participants with prediabetes also showed reductions in fasting insulin, insulin secretion over 2 h in response to an oral glucose tolerance test (OGTT) and an increase in both insulin sensitivity and HDL. No improvements
Department of Endocrinology, Fujian Provincial Hospital, Fujian, China
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Department of Endocrinology, Fujian Provincial Hospital, Fujian, China
Fujian Provincial Key Laboratory of Medical Analysis, Fujian Academy of Medical, Fujian, China
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), triglycerides (TG), alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP), and uric acid (UA). All subjects underwent oral glucose tolerance testing (OGTT), and fasting plasma glucose (FPG
Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France
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Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France
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Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France
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Committee instructions, and the study was approved by the Ethical Committee of Haute-Normandie (CCPPRB-HN; ( 26 )). The obese patients and the healthy volunteers underwent a 75-g oral glucose tolerance test (OGTT) after a 12-h fasting period. Plasma 26RFa
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. ( https://doi.org/10.1210/clinem/dgab019 ) 4 Lund A Bagger JI Christensen M Grondahl M van Hall G Holst JJ Vilsboll T Knop FK . Higher endogenous glucose production during OGTT vs Isoglycemic intravenous glucose infusion . Journal of
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2014 111 10761 – 10766 . ( https://doi.org/10.1073/pnas.1402663111 ) 34 Manell H Staaf J Manukyan L Kristinsson H Cen J Stenlid R Ciba I Forslund A & Bergsten P . Altered plasma levels of glucagon, GLP-1 and glicentin during OGTT
Tropical Institute of Reproductive Medicine, Cuiabá, Mato Grosso, Brazil
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P4 level was lower than 6.3 nmol/L ( 30 ). A glucose oxidase technique (Beckman Glucose Analyses, Fullerton, CA, USA) was used to measure fasting glucose. For the oral glucose tolerance test (OGTT), blood samples were collected at 0, 30, 60, 90, 120