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Hugo R Ramos
Hugo R Ramos
Department of Internal Medicine, Section of Metabolic Vascular Medicine, Division of Diabetes and Nutritional Sciences, Cardiovascular Endocrinology Laboratory, Faculty of Medicine, Hospital de Urgencias, National University of Córdoba, X5000 Córdoba, Argentina
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Andreas L Birkenfeld
Andreas L Birkenfeld
Department of Internal Medicine, Section of Metabolic Vascular Medicine, Division of Diabetes and Nutritional Sciences, Cardiovascular Endocrinology Laboratory, Faculty of Medicine, Hospital de Urgencias, National University of Córdoba, X5000 Córdoba, Argentina
Department of Internal Medicine, Section of Metabolic Vascular Medicine, Division of Diabetes and Nutritional Sciences, Cardiovascular Endocrinology Laboratory, Faculty of Medicine, Hospital de Urgencias, National University of Córdoba, X5000 Córdoba, Argentina
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Department of Internal Medicine, Section of Metabolic Vascular Medicine, Division of Diabetes and Nutritional Sciences, Cardiovascular Endocrinology Laboratory, Faculty of Medicine, Hospital de Urgencias, National University of Córdoba, X5000 Córdoba, Argentina
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Adolfo J de Bold
Adolfo J de Bold
Department of Internal Medicine, Section of Metabolic Vascular Medicine, Division of Diabetes and Nutritional Sciences, Cardiovascular Endocrinology Laboratory, Faculty of Medicine, Hospital de Urgencias, National University of Córdoba, X5000 Córdoba, Argentina
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The cNP act as a basic functional link between cardiovascular system homeostasis, inflammation and certain metabolic functions ( Fig. 1 ). Figure 1 Main biological targets and effects of the cardiac natriuretic peptides ANP and BNP. Increased secretion
Elizabeth Micks
Elizabeth Micks
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Greta B Raglan
Greta B Raglan
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Jay Schulkin
Jay Schulkin
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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, sometimes referred to as ‘membrane PRs’, which may act via inhibitory G-proteins (26) . Progestins in pregnancy Biochemical effects of progesterone in normal pregnancy In humans and some primates, unlike other mammals, labor is not precipitated by systemic
Monika Bilic
Monika Bilic
Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada
Department of Nutritional Sciences, University of Toronto, Toronto, Canada
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Department of Nutritional Sciences, University of Toronto, Toronto, Canada
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Huma Qamar
Huma Qamar
Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada
Department of Nutritional Sciences, University of Toronto, Toronto, Canada
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Department of Nutritional Sciences, University of Toronto, Toronto, Canada
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Akpevwe Onoyovwi
Akpevwe Onoyovwi
Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada
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Jill Korsiak
Jill Korsiak
Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada
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Eszter Papp
Eszter Papp
Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada
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Abdullah Al Mahmud
Abdullah Al Mahmud
Nutrition and Clinical Services Division, icddr,b, Dhaka, Bangladesh
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Rosanna Weksberg
Rosanna Weksberg
Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada
Molecular and Medical Genetics, University of Toronto, Toronto, Canada
Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, Canada
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Molecular and Medical Genetics, University of Toronto, Toronto, Canada
Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, Canada
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Alison D Gernand
Alison D Gernand
Department of Nutritional Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA
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Jennifer Harrington
Jennifer Harrington
Division of Endocrinology, Hospital for Sick Children, Toronto, Canada
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Daniel E Roth
Daniel E Roth
Centre for Global Child Health, Hospital for Sick Children, Toronto, Canada
Department of Nutritional Sciences, University of Toronto, Toronto, Canada
Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, Canada
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Department of Nutritional Sciences, University of Toronto, Toronto, Canada
Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, Canada
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studies in children and adults, it is unclear why there was no effect of prenatal supplementation on cord blood concentrations of IGF markers ( 13 , 20 , 21 , 22 ). It is possible that other factors (e.g., systemic inflammation) masked an effect or that
Xi Zhang
Xi Zhang
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Xiurong Shen
Xiurong Shen
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Wan Zhou
Wan Zhou
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Mengyun Xu
Mengyun Xu
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Yan Xing
Yan Xing
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Jianping Weng
Jianping Weng
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Shandong Ye
Shandong Ye
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Suowen Xu
Suowen Xu
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Zhi Zhang
Zhi Zhang
Hefei National Laboratory for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Wei Wang
Wei Wang
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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brain regions in both ob/ob mice and mice fed high-fat diets, the two classical models with metabolic disorders characterized by obesity, hyperglycemia, dyslipidemia, systemic inflammation, and neuroinflammation ( 10 , 18 , 19 ). LCN2-related reactive
Arpna Sharma
Arpna Sharma
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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Vijay Simha Baddela
Vijay Simha Baddela
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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Frank Becker
Frank Becker
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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Dirk Dannenberger
Dirk Dannenberger
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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Torsten Viergutz
Torsten Viergutz
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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Jens Vanselow
Jens Vanselow
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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). Catabolism and mobilization of stored triglycerides lead to increased systemic concentrations of non-esterified fatty acids (NEFA) like palmitic acid (PA, C16:0), stearic acid (SA, C18:0), oleic acid (OA, C18:1) and of β-hydroxybutyric acid (BHBA) ( 2 ). Such
Huma Qamar
Huma Qamar
Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada
Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
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Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
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Nandita Perumal
Nandita Perumal
Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada
Department of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
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Department of Epidemiology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
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Eszter Papp
Eszter Papp
Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada
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Alison D Gernand
Alison D Gernand
Department of Nutritional Sciences, Pennsylvania State University, University Park, Pennsylvania, USA
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Abdullah Al Mahmud
Abdullah Al Mahmud
Nutrition and Clinical Services Division, International Centre for Diarrhoeal Disease Research (icddr,b), Dhaka, Bangladesh
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Daniel E Roth
Daniel E Roth
Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada
Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
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Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
Department of Paediatrics, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
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, 30 ). Additional factors that may regulate PTH include magnesium and systemic inflammation markers such as C-reactive protein (CRP) ( 13 , 31 , 32 , 33 ). These factors may serve as points of intervention, for example, through modifying maternal
Stephen A Martin
Stephen A Martin
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Kenneth A Philbrick
Kenneth A Philbrick
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Carmen P Wong
Carmen P Wong
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Dawn A Olson
Dawn A Olson
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Adam J Branscum
Adam J Branscum
Biostatistics Program, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Donald B Jump
Donald B Jump
Molecular Nutrition and Diabetes Research Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Charles K Marik
Charles K Marik
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Jonathan M DenHerder
Jonathan M DenHerder
Carlson College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA
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Jennifer L Sargent
Jennifer L Sargent
Carlson College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA
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Russell T Turner
Russell T Turner
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Urszula T Iwaniec
Urszula T Iwaniec
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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higher osteoblast number rather than higher intrinsic osteoblast activity. These cellular markers of bone formation were co-incidental with higher serum osteocalcin, a systemic marker of bone formation ( Fig. 3G ). Mice housed at 32°C exhibited no change
Signe Kirkegaard
Signe Kirkegaard
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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Nanna Maria Uldall Torp
Nanna Maria Uldall Torp
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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Stig Andersen
Stig Andersen
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark
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Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark
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Stine Linding Andersen
Stine Linding Andersen
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
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attention to the manifestations of endometriosis outside the pelvis has evolved ( 13 ). In this approach, endometriosis is considered a chronic systemic disease with systemic inflammation and altered metabolism in the liver and adipose tissue as well as
Irfan Vardarli
Irfan Vardarli
Department of Medicine I, Klinikum Vest, Knappschaftskrankenhaus Recklinghausen, Academic Teaching Hospital, Ruhr-University Bochum, Recklinghausen, Germany
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Manuel Weber
Manuel Weber
Department of Nuclear Medicine, University Hospital Essen, Essen, Germany
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Frank Weidemann
Frank Weidemann
Department of Medicine I, Klinikum Vest, Knappschaftskrankenhaus Recklinghausen, Academic Teaching Hospital, Ruhr-University Bochum, Recklinghausen, Germany
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Dagmar Führer
Dagmar Führer
Department of Endocrinology, Diabetes and Metabolism, Clinical Chemistry – Division of Laboratory Research; Endocrine Tumor Center at WTZ/Comprehensive Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
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Ken Herrmann
Ken Herrmann
Department of Nuclear Medicine, University Hospital Essen, Essen, Germany
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Rainer Görges
Rainer Görges
Department of Nuclear Medicine, University Hospital Essen, Essen, Germany
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systemic inflammation . Journal of Clinical Endocrinology and Metabolism 1998 83 3296 – 3301 . ( https://doi.org/10.1210/jcem.83.9.5129 ) 15 Elisei R Bottici V Luchetti F Di Coscio G Romei C Grasso L Miccoli P Iacconi P Basolo F
Maria Giannakou
Maria Giannakou
Endocrine Unit, Department Med Therapeutics, Alexandra Hospital, School of Medicine, National Kapodistrian University, Athens, Greece
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Katerina Saltiki
Katerina Saltiki
Endocrine Unit, Department Med Therapeutics, Alexandra Hospital, School of Medicine, National Kapodistrian University, Athens, Greece
Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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Emily Mantzou
Emily Mantzou
Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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Eleni Loukari
Eleni Loukari
Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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Georgios Philippou
Georgios Philippou
Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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Konstantinos Terzidis
Konstantinos Terzidis
Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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Charalampos Stavrianos
Charalampos Stavrianos
Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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Miltiades Kyprianou
Miltiades Kyprianou
Endocrine Unit, Department Med Therapeutics, Alexandra Hospital, School of Medicine, National Kapodistrian University, Athens, Greece
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Theodora Psaltopoulou
Theodora Psaltopoulou
Department of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National Kapodistrian University, Athens, Greece
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Kalliopi Karatzi
Kalliopi Karatzi
Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens, Greece
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Maria Alevizaki
Maria Alevizaki
Endocrine Unit, Department Med Therapeutics, Alexandra Hospital, School of Medicine, National Kapodistrian University, Athens, Greece
Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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Department of Endocrinology and Metabolism, Athens University School of Medicine, Athens, Greece
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contribute to the increased oxidative stress in obesity are chronic low-grade inflammation, insulin resistance, hyperglycemia, elevated lipid levels, vitamin and mineral deficiencies, hyperleptinemia increased muscle activity, endothelial dysfunction and
