V Kenan Çelik
V Kenan Çelik
Department of Biochemistry, Cumhuriyet University School of Medicine, Sivas, Turkey
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Sercan Kapancık
Sercan Kapancık
Department of Biochemistry, Cumhuriyet University School of Medicine, Sivas, Turkey
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Turgut Kaçan
Turgut Kaçan
Department of Medical Oncology, High Specialized Education and Research Hospital, Bursa, Turkey
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Selen Baloglu Kaçan
Selen Baloglu Kaçan
Department of Internal Medicine, Afyonkarahisar State Hospital, Afyon, Turkey
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Serkan Kapancık
Serkan Kapancık
Department of Biochemistry, Cumhuriyet University School of Medicine, Sivas, Turkey
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Hasan Kılıçgün
Hasan Kılıçgün
Department of Nutrition and Dietetics, Health Science Faculty, University of Erzincan, Erzincan, Turkey
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. Recent studies have clearly shown that polyamines affect many systems such as almost all ionotropic receptors (NMDA, Kainate, AMPA, H + ) and K + , Na + , Ca 2+ channels and thus play a central role in the formation of homeostatic response to the major
Xi Zhang
Xi Zhang
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Xiurong Shen
Xiurong Shen
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Wan Zhou
Wan Zhou
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Mengyun Xu
Mengyun Xu
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Yan Xing
Yan Xing
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Jianping Weng
Jianping Weng
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Shandong Ye
Shandong Ye
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Suowen Xu
Suowen Xu
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Zhi Zhang
Zhi Zhang
Hefei National Laboratory for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Wei Wang
Wei Wang
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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, increased morbidity, and huge economic burdens. A variety of factors related to the pathophysiological processes of T2D including hyperglycemia, the formation of intracellular advanced glycation end products, oxidative stress, mitochondrial dysfunction, and
Alexander V Amram
Alexander V Amram
Department of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA
Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Stephen Cutie
Stephen Cutie
Department of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA
Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Guo N Huang
Guo N Huang
Department of Physiology, Cardiovascular Research Institute, University of California, San Francisco, San Francisco, California, USA
Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, California, USA
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pituitary gland, which bind tissue-specific isoforms of their cognate receptor, the glucocorticoid receptor (GR), and activate cell-specific stress–response pathways ( 46 ). The primary forms of glucocorticoids in humans and rodents are cortisol and
Peiwen Zheng
Peiwen Zheng
School of Mental Health, Wenzhou Medical University, The Affiliated Kangning Hospital, Wenzhou, China
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Fan Wang
Fan Wang
Beijing Hui-Long-Guan Hospital, Peking University, Beijing, China
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Hui Li
Hui Li
Psychosomatic Medicine Research Division, Inner Mongolia Medical University, Huhhot, China
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Hanlu Chen
Hanlu Chen
School of Mental Health, Wenzhou Medical University, The Affiliated Kangning Hospital, Wenzhou, China
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Mengtong Li
Mengtong Li
School of Mental Health, Wenzhou Medical University, The Affiliated Kangning Hospital, Wenzhou, China
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Haozheng Ma
Haozheng Ma
School of Mental Health, Wenzhou Medical University, The Affiliated Kangning Hospital, Wenzhou, China
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Jue He
Jue He
School of Mental Health, Wenzhou Medical University, The Affiliated Kangning Hospital, Wenzhou, China
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Li Chen
Li Chen
School of Mental Health, Wenzhou Medical University, The Affiliated Kangning Hospital, Wenzhou, China
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Yanlong Liu
Yanlong Liu
School of Mental Health, Wenzhou Medical University, The Affiliated Kangning Hospital, Wenzhou, China
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Haiyun Xu
Haiyun Xu
School of Mental Health, Wenzhou Medical University, The Affiliated Kangning Hospital, Wenzhou, China
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C Hench J Tolnay M Neutzner A , et al. Neuronal mitochondrial dysfunction activates the integrated stress response to induce fibroblast growth factor 21 . Cell Reports 2018 24 1407 – 1414 . ( https://doi.org/10.1016/j.celrep.2018
Kylie D Rock
Kylie D Rock
Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA
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Brian Horman
Brian Horman
Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA
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Allison L Phillips
Allison L Phillips
Nicholas School of the Environment, Duke University, Durham, North Carolina, USA
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Susan L McRitchie
Susan L McRitchie
NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
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Scott Watson
Scott Watson
NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
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Jocelin Deese-Spruill
Jocelin Deese-Spruill
NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
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Dereje Jima
Dereje Jima
Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA
Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, USA
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Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, USA
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Susan Sumner
Susan Sumner
NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA
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Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA
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Heather M Stapleton
Heather M Stapleton
Nicholas School of the Environment, Duke University, Durham, North Carolina, USA
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Heather B Patisaul
Heather B Patisaul
Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA
Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA
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Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA
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investigating the mechanisms by which prenatal stress alters neurodevelopment ( 67 ). A series of studies has shown that stress-induced upregulation of these placental inflammatory response genes is consistently male biased ( 15 , 67 ) and can result in
Esben Thyssen Vestergaard
Esben Thyssen Vestergaard
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Morten B Krag
Morten B Krag
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Morten M Poulsen
Morten M Poulsen
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Steen B Pedersen
Steen B Pedersen
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Niels Moller
Niels Moller
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Jens Otto Lunde Jorgensen
Jens Otto Lunde Jorgensen
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Niels Jessen
Niels Jessen
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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response to insulin infusion in the saline study (43.2±4.3 (baseline) vs 40.4±4.2 (clamp), P <0.001), whereas concomitant ghrelin infusion abrogated this suppressive effect of insulin on RBP4 (mg/l; 42.4±4.5 (baseline) vs 42.9±4.7 (clamp), P =0.73; Fig
M von Wolff
M von Wolff
Division of Gynaecological Endocrinology and Reproductive Medicine, University Women’s Hospital, Bern University Hospital, University of Bern, Bern, Switzerland
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C T Nakas
C T Nakas
University Institute of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
Laboratory of Biometry, University of Thessaly, Volos, Greece
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Laboratory of Biometry, University of Thessaly, Volos, Greece
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M Tobler
M Tobler
Division of Gynaecological Endocrinology and Reproductive Medicine, University Women’s Hospital, Bern University Hospital, University of Bern, Bern, Switzerland
Division of Pneumology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
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Division of Pneumology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
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T M Merz
T M Merz
Division of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
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M P Hilty
M P Hilty
Intensive Care Unit, University Hospital, Zurich, Switzerland
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J D Veldhuis
J D Veldhuis
Endocrine Research Unit, Department of Internal Medicine, Mayo School of Graduate Medical Education, Centre for Translational Science Activities, Mayo Clinic, Rochester, New York, USA
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A R Huber
A R Huber
Centre for Laboratory Medicine, Cantonal Hospital, Aarau, Switzerland
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J Pichler Hefti
J Pichler Hefti
Division of Pneumology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
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shown in Figs 1 and 2 for cortisol and fT4. Figure 1 Cortisol concentration (nmol/L), representing a stress axis. Effect of altitude at 550 m before the expedition (PR), during ascent at 4.844 m (BC1), 6.022 m (C2) and 7.050 m altitude (C3
Stephen A Martin
Stephen A Martin
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Kenneth A Philbrick
Kenneth A Philbrick
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Carmen P Wong
Carmen P Wong
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Dawn A Olson
Dawn A Olson
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Adam J Branscum
Adam J Branscum
Biostatistics Program, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Donald B Jump
Donald B Jump
Molecular Nutrition and Diabetes Research Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Charles K Marik
Charles K Marik
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
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Jonathan M DenHerder
Jonathan M DenHerder
Carlson College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA
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Jennifer L Sargent
Jennifer L Sargent
Carlson College of Veterinary Medicine, Oregon State University, Corvallis, Oregon, USA
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Russell T Turner
Russell T Turner
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Urszula T Iwaniec
Urszula T Iwaniec
Skeletal Biology Laboratory, School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon, USA
Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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Center for Healthy Aging Research, Oregon State University, Corvallis, Oregon, USA
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facultative daily heterotherms and experience fasting-induced reductions in body temperature when subjected to housing temperatures below their thermoneutral zones ( 20 ). In response to cold stress, sympathetic nervous system activation and catecholaminergic
Filippo Ceccato
Filippo Ceccato
Department of Medicine DIMED, University of Padova, Padova, Italy
Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
Department of Neuroscience DNS, University of Padova, Padova, Italy
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Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
Department of Neuroscience DNS, University of Padova, Padova, Italy
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Elisa Selmin
Elisa Selmin
Department of Medicine DIMED, University of Padova, Padova, Italy
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Giorgia Antonelli
Giorgia Antonelli
Department of Medicine DIMED, University of Padova, Padova, Italy
Laboratory Medicine, University-Hospital of Padova, Padova, Italy
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Laboratory Medicine, University-Hospital of Padova, Padova, Italy
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Mattia Barbot
Mattia Barbot
Department of Medicine DIMED, University of Padova, Padova, Italy
Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
Department of Neuroscience DNS, University of Padova, Padova, Italy
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Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
Department of Neuroscience DNS, University of Padova, Padova, Italy
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Andrea Daniele
Andrea Daniele
Department of Medicine DIMED, University of Padova, Padova, Italy
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Marco Boscaro
Marco Boscaro
Department of Medicine DIMED, University of Padova, Padova, Italy
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Mario Plebani
Mario Plebani
Department of Medicine DIMED, University of Padova, Padova, Italy
Laboratory Medicine, University-Hospital of Padova, Padova, Italy
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Laboratory Medicine, University-Hospital of Padova, Padova, Italy
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Carla Scaroni
Carla Scaroni
Department of Medicine DIMED, University of Padova, Padova, Italy
Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
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Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
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treatment was suggested. They were well-educated individuals aware of their incomplete HPA axis response: they were advised to take GC therapy only in the event of illness, body temperature > 38°C, major/minor surgery, endoscopic procedures, or other events
Paraskevi Kazakou
Paraskevi Kazakou
Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Stavroula A Paschou
Stavroula A Paschou
Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Theodora Psaltopoulou
Theodora Psaltopoulou
Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Maria Gavriatopoulou
Maria Gavriatopoulou
Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Eleni Korompoki
Eleni Korompoki
Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Katerina Stefanaki
Katerina Stefanaki
Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Fotini Kanouta
Fotini Kanouta
Department of Endocrinology, Alexandra Hospital, Athens, Greece
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Georgia N Kassi
Georgia N Kassi
Department of Endocrinology, Alexandra Hospital, Athens, Greece
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Meletios-Athanasios Dimopoulos
Meletios-Athanasios Dimopoulos
Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Asimina Mitrakou
Asimina Mitrakou
Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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SARS-CoV-2 infection and monocyte response through a HIF-1α/glycolysis-dependent axis . Cell Metabolism 2020 32 498 – 499 . ( https://doi.org/10.1016/j.cmet.2020.07.015 ) 30 Dungan KM Braithwaite SS Preiser JC . Stress hyperglycaemia . Lancet
