Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland
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The Key Laboratory of Systems Biomedicine, Ministry of Education, and Exercise Translational Medicine Center, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China
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Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland
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Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland
The Key Laboratory of Systems Biomedicine, Ministry of Education, and Exercise Translational Medicine Center, Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China
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Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland
Department of Epidemiology and Biostatistics, Centre for Environment and Health, School of Public Health, Imperial College London, London, UK
Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland
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Introduction Sex steroids are important regulators of pubertal development and their biological action is governed by sex hormone-binding globulin (SHBG) ( 1 ). Serum SHBG levels rise from birth to early childhood, then decline in early
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cortisone ([1,2- 3 H]-cortisone 60 Ci/mmol; American Radiolabeled Chemicals Inc., Tokyo, Japan). After culturing, the medium was recovered and the steroids were extracted once with 1 mL diethyl ether for 5 min. The organic phase was removed and evaporated at
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steroidogenesis to the total circulating steroid pool ( 23 ). In the present study, when a cohort of women with PCOS was classified into two subgroups according to DHEA-S concentrations, no significant difference was observed between them in insulin resistance
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
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Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
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Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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present in the uterus and placenta where they can influence implantation and pregnancy as well as maternal–fetal transmission of metabolites ( 6 , 7 ). It has been demonstrated that various stages of implantation are profoundly regulated by steroids
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catecholamine synthesis-associated genes were considered DEG, several genes associated with the regulation of neurotransmitter secretion (GO:0046928, fold enrichment of 4.0, FDR P = 0.000407) were included in the Dex-upregulated genes. Regarding steroid
Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA
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Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA
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Introduction Dehydroepiandrosterone (DHEA) is a steroid hormone that is sometimes called the ‘anti-aging hormone’ because of ts protective effects on memory, neuronal growth, and neuronal activity ( 1 ). DHEA is produced both centrally, as a
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steroid ring of estrogen produces a cascade of metabolites with diverse biological properties, such as 2-hydroxyestrone (2-OHE1), 4-hydroxyestrone (4-OHE1), and 16α-hydroxyestrone (16α-OHE1). These hydroxylated metabolites can be further methylated into
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effects associated to treatment were either directly related to the drug intake (nausea, vomiting, dizziness, sedation, headache) or secondary to the metyrapone-induced alteration of steroid synthesis (hirsutism, hypertension) ( 8 , 9 ). In patients
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Department of Pharmacology, Department of Biology, Toxicology and Therapeutics, School of Medicine, University of Kansas Medical Center, Room 4061 of KLSIC Building, 2146 West 39th Street, Kansas City, Kansas 66160, USA
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chromatography and GC–MS – II. Fractionation and quantitation of the main groups of estrogen conjugates . Journal of Steroid Biochemistry 1987 28 215 – 226 . ( doi:10.1016/0022-4731(87)90380-3 ). 21 Zhou R Lai Y Yamabe N Fukui M Zhu BT . Estriol
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on mood and behaviour. Steroids in the brain The spectrum of structures and functions of neurosteroids is so wide as to form a branch of endocrinology (or at least paracrinology) in its own right. Many are locally synthesized, although usually