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, confirmed the utility of TSH suppressive therapy in patients at high risk of recurrence ( 12 , 13 ). Finally, the most recent analyses of the same registry data in 4941 patients (median follow-up of 6 years) showed no benefit on survival when comparing
Department of Breast Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China
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Department of Surgery, Second People's Hospital of Guizhou Province, Guiyang, Guizhou, China
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follow-ups and enhanced treatments might be conducted to delay the recurrence and distant metastasis and improve patients’ survival rate. Currently, the investigations of FOXP4 in other cancers have revealed that FOXP4 plays an important role as a key
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thyroid cancer cases. The majority of FTC patients have excellent prognoses when their cancers are caught early. However, the relative 5-year survival rate drops dramatically to about 50% for patients with advanced metastatic cancer who does not respond to
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Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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of high-functioning islets exhibited an increased sensitivity to hypoxia and cytokines leading to reduced survival upon stress ( 9 ). Also, islet lesions have been shown to be of a heterogeneous nature and the beta cell loss in type 2 diabetes (T2D
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since. At the last follow-up, there was diminished radiotracer uptake by both metastases on PET-Ga-DOTANOC. After 4 years of follow-up, the patient is free from recurrence and shows stable slightly elevated calcium of 10.4 mg/dL and PTH levels of 54
Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands
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Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
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Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Endocrinology Clinic, Cluj County Emergency Hospital, Cluj-Napoca, Romania
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Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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-AKT-mTOR pathway, obesity, and breast cancer disease-free survival . Breast Cancer Research and Treatment 2014 147 381 – 387 . ( https://doi.org/10.1007/s10549-014-3081-9 ) 25108739 31 Pfisterer K Fusi A Klinghammer K Knodler M Nonnenmacher A
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in vitro . Introduction Thyroid cancer is a common endocrine malignant cancer ( 1 ). The survival of patients with thyroid cancer has improved with the combined therapy of surgery and radioactive iodine (RAI) therapy. However, the
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bioavailability and signaling, such as transporters, integrins, deiodinases, nuclear receptors, coregulators, among others. Circulating levels of hormones and their transporters determine the relation of free hormone/total hormone in serum, while T4 and/or T3
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). Our data are similar to those reported on colorectal cancer, where BRIP1 overexpression correlated with poor recurrence-free survival ( 40 ). Also, elevated expression of BRIP1 was observed in high-grade breast tumors correlated with an unfavorable
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, recurrence and death is well established ( 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ). In the majority of cases, para-pneumonic hyponatremia is sustained by a syndrome of inappropriate anti-diuresis (SIAD), where hypoxia and inflammatory cytokines, such as