Katarzyna Wyskida
Katarzyna Wyskida
Health Promotion and Obesity Management Unit, Department of Pathophysiology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland
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Grzegorz Franik
Grzegorz Franik
Department of Gynecological Endocrinology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland
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Tomasz Wikarek
Tomasz Wikarek
Department of Gynecology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland
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Aleksander Owczarek
Aleksander Owczarek
Department of Statistics, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, Katowice, Poland
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Alham Delroba
Alham Delroba
Health Promotion and Obesity Management Unit, Department of Pathophysiology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland
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Jerzy Chudek
Jerzy Chudek
Pathophysiology Unit, Department of Pathophysiology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland
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Jerzy Sikora
Jerzy Sikora
Department of Perinatology and Gynecology, Medical University of Silesia, Katowice, Poland
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Magdalena Olszanecka-Glinianowicz
Magdalena Olszanecka-Glinianowicz
Health Promotion and Obesity Management Unit, Department of Pathophysiology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland
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mass index (BMI) during the 3-month period before the study. Patients diagnosed with polycystic ovary syndrome (PCOS), Cushing’s syndrome, thyroid dysfunctions, androgen-secreting tumor, and enzyme deficiency (21-hydroxylase in particular), decreased
Yali Cheng
Yali Cheng
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Qiaoying Lv
Qiaoying Lv
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Bingying Xie
Bingying Xie
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Bingyi Yang
Bingyi Yang
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Weiwei Shan
Weiwei Shan
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Chengcheng Ning
Chengcheng Ning
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Bing Li
Bing Li
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Liying Xie
Liying Xie
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Chao Gu
Chao Gu
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Xuezhen Luo
Xuezhen Luo
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Xiaojun Chen
Xiaojun Chen
Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
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Qin Zhu
Qin Zhu
Department of Pathology, Obstetrics and Gynecology, Hospital of Fudan University, Shanghai, China
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( 17 ), type 2 diabetes mellitus ( 18 ) and polycystic ovary syndrome (PCOS) ( 10 ), is the risk factor for EC. A prospective cohort study notes that ‘insulin resistance/metabolic syndrome,’ ‘steroids,’ and ‘inflammation’ factors are the three risk
Davoud Jafari-Gharabaghlou
Davoud Jafari-Gharabaghlou
Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Mostafa Vaghari-Tabari
Mostafa Vaghari-Tabari
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Hajar Oghbaei
Hajar Oghbaei
Department of Physiology, Tabriz University of Medical Sciences, Tabriz, Iran
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Laura Lotz
Laura Lotz
Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen–Nürnberg, Erlangen, Germany
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Reza Zarezadeh
Reza Zarezadeh
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Yeganeh Rastgar Rezaei
Yeganeh Rastgar Rezaei
Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
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Mahnaz Ranjkesh
Mahnaz Ranjkesh
Medical Radiation Science Research Group (MRSRG), Tabriz University of Medical Sciences, Tabriz, Iran
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Mohammad Nouri
Mohammad Nouri
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
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Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
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Amir Fattahi
Amir Fattahi
Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen–Nürnberg, Erlangen, Germany
Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
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Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
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Saba Nikanfar
Saba Nikanfar
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Ralf Dittrich
Ralf Dittrich
Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen–Nürnberg, Erlangen, Germany
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well documented that obesity or excess fat can negatively influence female fertility and ovarian function such as what we see in obese women with polycystic ovary syndrome (PCOS) ( 10 , 11 ). The role of adipokines has also been shown in embryo
Nancy J Olsen
Nancy J Olsen
Division of Rheumatology, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, Milton S Hershey Medical Center, The Pennsylvania State University, Mail Code H044, 500 University Drive, Hershey, Pennsylvania 17033-0850, USA
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Ann L Benko
Ann L Benko
Division of Rheumatology, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, Milton S Hershey Medical Center, The Pennsylvania State University, Mail Code H044, 500 University Drive, Hershey, Pennsylvania 17033-0850, USA
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William J Kovacs
William J Kovacs
Division of Rheumatology, Division of Endocrinology, Diabetes, and Metabolism, College of Medicine, Milton S Hershey Medical Center, The Pennsylvania State University, Mail Code H044, 500 University Drive, Hershey, Pennsylvania 17033-0850, USA
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-chromosome inactivation in Australian Caucasian women with infertility related to polycystic ovary syndrome . Journal of Clinical Endocrinology and Metabolism 2002 87 161 – 165 . ( doi:10.1210/jcem.87.1.8137 ). 32 Olsen NJ Li Q-Z Quan J Wang L Mutwally A
M Boering
M Boering
Isala, Diabetes Centre, Zwolle, The Netherlands
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P R van Dijk
P R van Dijk
Isala, Diabetes Centre, Zwolle, The Netherlands
Isala, Department of Internal Medicine, Zwolle, The Netherlands
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Isala, Department of Internal Medicine, Zwolle, The Netherlands
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S J J Logtenberg
S J J Logtenberg
Diakonessenhuis, Department of Internal Medicine, Utrecht, The Netherlands
Langerhans Medical Research group, Zwolle, The Netherlands
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Langerhans Medical Research group, Zwolle, The Netherlands
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K H Groenier
K H Groenier
Isala, Diabetes Centre, Zwolle, The Netherlands
Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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B H R Wolffenbuttel
B H R Wolffenbuttel
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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R O B Gans
R O B Gans
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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N Kleefstra
N Kleefstra
Isala, Diabetes Centre, Zwolle, The Netherlands
Langerhans Medical Research group, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Langerhans Medical Research group, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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H J G Bilo
H J G Bilo
Isala, Diabetes Centre, Zwolle, The Netherlands
Isala, Department of Internal Medicine, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Isala, Department of Internal Medicine, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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treatment withdrew informed consent shortly after implantation of the insulin pump. As a result, 23 patients completed the follow-up period ( 23 ). For the current analysis, patients with a known history of polycystic ovary syndrome (PCOS), hirsutism
Agnieszka Adamska
Agnieszka Adamska
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland
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Paulina Tomczuk-Bobik
Paulina Tomczuk-Bobik
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland
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Anna Beata Popławska-Kita
Anna Beata Popławska-Kita
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland
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Katarzyna Siewko
Katarzyna Siewko
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland
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Angelika Buczyńska
Angelika Buczyńska
Clinical Research Centre, Medical University of Bialystok, Białystok, Poland
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Piotr Szumowski
Piotr Szumowski
Department of Nuclear Medicine, Medical University of Białystok, Białystok, Poland
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Łukasz Żukowski
Łukasz Żukowski
Department of Nuclear Medicine, Medical University of Białystok, Białystok, Poland
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Janusz Myśliwiec
Janusz Myśliwiec
Department of Nuclear Medicine, Medical University of Białystok, Białystok, Poland
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Monika Zbucka-Krętowska
Monika Zbucka-Krętowska
Department of Gynecological Endocrinology and Adolescent Gynecology, Medical University of Bialystok, Białystok, Poland
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Marcin Adamski
Marcin Adamski
Faculty of Computer Science, Bialystok University of Technology, Białystok, Poland
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Adam Jacek Krętowski
Adam Jacek Krętowski
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Białystok, Poland
Clinical Research Centre, Medical University of Bialystok, Białystok, Poland
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Clinical Research Centre, Medical University of Bialystok, Białystok, Poland
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indicated for ovarian cancer), polycystic ovarian syndrome (two women), pregnancy (two women), breastfeeding (one woman), use of hormonal contraception (three women), and history of previous RAI (two women), radiotherapy, or other medical treatment or
Min Li
Min Li
Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
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Ying Chen
Ying Chen
Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
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Jingjing Jiang
Jingjing Jiang
Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
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Yan Lu
Yan Lu
Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
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Zhiyi Song
Zhiyi Song
Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shengjie Zhang
Shengjie Zhang
CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Chao Sun
Chao Sun
CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Hao Ying
Hao Ying
CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China
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Xiaofang Fan
Xiaofang Fan
Department of Endocrinology and Metabolism, Minhang Branch, Zhongshan Hospital, Central Hospital of Minhang District, Shanghai Minhang Hospital, Fudan University, Shanghai, China
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Yuping Song
Yuping Song
Department of Endocrinology and Metabolism, Minhang Branch, Zhongshan Hospital, Central Hospital of Minhang District, Shanghai Minhang Hospital, Fudan University, Shanghai, China
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Jialin Yang
Jialin Yang
Department of Endocrinology and Metabolism, Minhang Branch, Zhongshan Hospital, Central Hospital of Minhang District, Shanghai Minhang Hospital, Fudan University, Shanghai, China
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Lin Zhao
Lin Zhao
Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China
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human cohorts revealed that Nrg4 levels were increased in patients with prediabetes, newly diagnosed diabetes, gestational diabetes or polycystic ovary syndrome, suggesting Nrg4 concentrations were associated with the development and progression of
Chun-feng Lu
Chun-feng Lu
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Xiao-qin Ge
Xiao-qin Ge
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Yan Wang
Yan Wang
Department of Geriatrics, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Jian-bin Su
Jian-bin Su
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Xue-qin Wang
Xue-qin Wang
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Dong-mei Zhang
Dong-mei Zhang
Clinical Medicine Research Center, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Feng Xu
Feng Xu
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Wang-shu Liu
Wang-shu Liu
Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China
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Min Su
Min Su
Department of Endocrinology, Nantong Hospital of Traditional Chinese Medicine, Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Nantong, China
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complications. Multiple studies have revealed that serum ADA levels are associated with IR in patients with T2D ( 19 ) and in patients with polycystic ovary syndrome ( 20 ). The underlying mechanism may be that adenosine, the substrate of ADA, can promote
A Bergougnoux
A Bergougnoux
Service de Génétique Moléculaire et de Cytogénétique, Centre Hospitalier Universitaire de Montpellier, Université de Montpellier, Montpellier, France
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L Gaspari
L Gaspari
Département d'Endocrinologie et de Gynécologie Pédiatrique, Hôpital Arnaud de Villeneuve, Université de Montpellier, Montpellier, France
INSERM Unité 1203 (DEFE), Université de Montpellier, Montpellier, France
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INSERM Unité 1203 (DEFE), Université de Montpellier, Montpellier, France
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M Soleirol
M Soleirol
Département de Pediatrie, CHU Nîmes, France, Université de Montpellier Faculté de Médecine Montpellier-Nîmes, Montpellier, France
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N Servant
N Servant
Service de Génétique Moléculaire et de Cytogénétique, Centre Hospitalier Universitaire de Montpellier, Université de Montpellier, Montpellier, France
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S Soskin
S Soskin
Département de Pédiatrie, Centre Hospitalier Universitaire Hautepierre de Strasbourg, Strasbourg, France
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S Rossignol
S Rossignol
Département de Pédiatrie, Centre Hospitalier Universitaire Hautepierre de Strasbourg, Strasbourg, France
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K Wagner-Mahler
K Wagner-Mahler
Département de Pédiatrie, CHU Nice, Hôpitaux Pédiatriques de Nice CHU-Lenval, Nice, France
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J Bertherat
J Bertherat
Department of Endocrinology, French Reference Center for Rare Adrenal Disorders, Hôpital Cochin, Université Paris Cité, Institut Cochin, Assitance Publique-Hôpitaux de Paris, Paris, France
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C Sultan
C Sultan
Département d'Endocrinologie et de Gynécologie Pédiatrique, Hôpital Arnaud de Villeneuve, Université de Montpellier, Montpellier, France
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N Kalfa
N Kalfa
Department of Pediatric Urological Surgery, French Reference Center for abnormalities of Genital Development (DevGen), CHU Lapeyronie, Montpellier University, Montpellier, France
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F Paris
F Paris
Service de Génétique Moléculaire et de Cytogénétique, Centre Hospitalier Universitaire de Montpellier, Université de Montpellier, Montpellier, France
Département d'Endocrinologie et de Gynécologie Pédiatrique, Hôpital Arnaud de Villeneuve, Université de Montpellier, Montpellier, France
INSERM Unité 1203 (DEFE), Université de Montpellier, Montpellier, France
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Département d'Endocrinologie et de Gynécologie Pédiatrique, Hôpital Arnaud de Villeneuve, Université de Montpellier, Montpellier, France
INSERM Unité 1203 (DEFE), Université de Montpellier, Montpellier, France
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hyperandrogenism warrant investigations to rule out an adrenal or ovarian disorder, particularly polycystic ovary syndrome and nonclassical congenital adrenal hyperplasia ( 2 , 3 ). In few patients, the clinical expression of hyperandrogenism is more severe with
Martijn J J Finken
Martijn J J Finken
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
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Aleid J G Wirix
Aleid J G Wirix
Department of Public and Occupational Health, EMGO Institute for Health and Care Research, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
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Ines A von Rosenstiel-Jadoul
Ines A von Rosenstiel-Jadoul
Department of Pediatrics, Rijnstate Hospital, Arnhem, The Netherlands
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Bibian van der Voorn
Bibian van der Voorn
Department of Pediatric Endocrinology and Obesity Center CGG, Erasmus MC Sophia Children’s Hospital, Rotterdam, The Netherlands
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Mai J M Chinapaw
Mai J M Chinapaw
Department of Public and Occupational Health, EMGO Institute for Health and Care Research, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
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Michaela F Hartmann
Michaela F Hartmann
Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics, Department of Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, Justus Liebig University, Giessen, Germany
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Joana E Kist-van Holthe
Joana E Kist-van Holthe
Department of Public and Occupational Health, EMGO Institute for Health and Care Research, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
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Stefan A Wudy
Stefan A Wudy
Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics, Department of Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, Justus Liebig University, Giessen, Germany
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Joost Rotteveel
Joost Rotteveel
Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
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.2337/db08-0094 ) 33 Wu C Wei K Jiang Z . 5Alpha-reductase activity in women with polycystic ovary syndrome: a systematic review and meta-analysis . Reproductive Biology and Endocrinology 2017 15 21. ( https://doi.org/10.1186/s12958
