Lei Gao
Lei Gao
Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Wenxia Cui
Wenxia Cui
Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Dinghuang Mu
Dinghuang Mu
Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
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Shaoping Li
Shaoping Li
Department of Health Management Center, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Nan Li
Nan Li
Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Weihong Zhou
Weihong Zhou
Department of Health Management Center, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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Yun Hu
Yun Hu
Department of Geriatrics, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
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correlated with MASLD risk. A recent study using liquid chromatography–mass spectrometry found that the HDL content of patients with MASLD was decreased, and the lipid composition of HDL differed from that of control subjects ( 23 ). A variety of liver
Stine A Holmboe
Stine A Holmboe
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Ravi Jasuja
Ravi Jasuja
Research Program in Men’s Health: Aging and Metabolism, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, USA
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Brian Lawney
Brian Lawney
Research Program in Men’s Health: Aging and Metabolism, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, USA
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Lærke Priskorn
Lærke Priskorn
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Niels Joergensen
Niels Joergensen
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Allan Linneberg
Allan Linneberg
Centre for Clinical Research and Prevention, Frederiksberg Hospital, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Tina Kold Jensen
Tina Kold Jensen
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark
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Niels Erik Skakkebæk
Niels Erik Skakkebæk
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Anna-Maria Andersson
Anna-Maria Andersson
Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark
The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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The International Research Centre in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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reliable compared to methods based on liquid or gas chromatography tandem mass spectrometry, which today are recommended for analyses of small molecules like steroid hormones ( 1 , 33 ). The main problem of immunoassays relates to their tendency of
Bruno Donadille
Bruno Donadille
Service d’Endocrinologie et Médecine de la Reproduction, Centre de Référence des Maladies Endocrines Rares de la Croissance, Hôpital Saint Antoine, Groupe Hospitalier Universitaire Est, AP-HP, Paris, France
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Muriel Houang
Muriel Houang
Service d’Explorations Fonctionnelles Endocriniennes, Centre de Référence des Maladies Endocrines Rares de la Croissance, Hôpital Trousseau, Groupe Hospitalier Universitaire Est, AP-HP, Paris, France
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Irène Netchine
Irène Netchine
Service d’Explorations Fonctionnelles Endocriniennes, Centre de Référence des Maladies Endocrines Rares de la Croissance, Hôpital Trousseau, Groupe Hospitalier Universitaire Est, AP-HP, Paris, France
Université Pierre et Marie Curie, Sorbonne Université, Paris, France
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Université Pierre et Marie Curie, Sorbonne Université, Paris, France
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Jean-Pierre Siffroi
Jean-Pierre Siffroi
Université Pierre et Marie Curie, Sorbonne Université, Paris, France
INSERM UMR_S933, Paris, France
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INSERM UMR_S933, Paris, France
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Sophie Christin-Maitre
Sophie Christin-Maitre
Service d’Endocrinologie et Médecine de la Reproduction, Centre de Référence des Maladies Endocrines Rares de la Croissance, Hôpital Saint Antoine, Groupe Hospitalier Universitaire Est, AP-HP, Paris, France
Université Pierre et Marie Curie, Sorbonne Université, Paris, France
INSERM UMR_S933, Paris, France
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Université Pierre et Marie Curie, Sorbonne Université, Paris, France
INSERM UMR_S933, Paris, France
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evaluations have been performed using liquid chromatography-mass spectrometry (LC–MS/MS), which allows steroid hormone analysis of sixteen analytes from a single sample in 150 µL of serum, as previously described ( 6 , 7 , 9 ). Semen was obtained after 4
Charlotte Höybye
Charlotte Höybye
Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden
Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden
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Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden
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Erik Wahlström
Erik Wahlström
Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden
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Petra Tollet-Egnell
Petra Tollet-Egnell
Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden
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Gunnar Norstedt
Gunnar Norstedt
Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden
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Introduction Metabolomics is an exciting new analytical field in systems biology, which uses techniques such as mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy to define the pattern of low-molecular weight compounds (LMCs
Agnieszka Adamska
Agnieszka Adamska
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland
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Vitalii Ulychnyi
Vitalii Ulychnyi
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland
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Katarzyna Siewko
Katarzyna Siewko
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland
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Anna Popławska-Kita
Anna Popławska-Kita
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland
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Małgorzata Szelachowska
Małgorzata Szelachowska
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland
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Marcin Adamski
Marcin Adamski
Faculty of Computer Science, Bialystok University of Technology, Białystok, Poland
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Angelika Buczyńska
Angelika Buczyńska
Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland
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Adam Jacek Krętowski
Adam Jacek Krętowski
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Białystok, Bialystok, Poland
Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland
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Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland
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did not measure 24 h UFC levels with liquid Chromatography with tandem mass spectrometry but via the chemiluminescent microparticle immunoassay method. The strengths of this study are the relatively large sample size and robust inclusion criteria
Marta Araujo-Castro
Marta Araujo-Castro
Department of Endocrinology & Nutrition, Hospital Universitario Ramón y Cajal & Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
University of Alcalá, Madrid, Spain
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University of Alcalá, Madrid, Spain
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Miguel Paja Fano
Miguel Paja Fano
Department of Endocrinology & Nutrition, OSI Bilbao-Basurto, Hospital Universitario de Basurton & Basque Country University, Medicine Department, Bilbao, Spain
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Begoña Pla Peris
Begoña Pla Peris
Department of Endocrinology & Nutrition, Hospital Universitario de Castellón, Castellón, Spain
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Marga González Boillos
Marga González Boillos
Department of Endocrinology & Nutrition, Hospital Universitario de Castellón, Castellón, Spain
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Eider Pascual-Corrales
Eider Pascual-Corrales
Department of Endocrinology & Nutrition, Hospital Universitario Ramón y Cajal & Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
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Ana María García-Cano
Ana María García-Cano
Department of Biochemistry, Hospital Universitario Ramón y Cajal, Madrid, Spain
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Paola Parra Ramírez
Paola Parra Ramírez
Department of Endocrinology & Nutrition, Hospital Universitario La Paz Madrid, Spain
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Patricia Martín Rojas-Marcos
Patricia Martín Rojas-Marcos
Department of Endocrinology & Nutrition, Hospital Universitario La Paz Madrid, Spain
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Jorge Gabriel Ruiz-Sanchez
Jorge Gabriel Ruiz-Sanchez
Department of Endocrinology & Nutrition, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain
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Almudena Vicente
Almudena Vicente
Department of Endocrinology & Nutrition, Hospital Universitario de Toledo, Toledo, Spain
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Emilia Gómez-Hoyos
Emilia Gómez-Hoyos
Department of Endocrinology & Nutrition, Hospital Universitario de Valladolid, Valladolid, Spain
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Rui Ferreira
Rui Ferreira
Department of Endocrinology & Nutrition, Hospital Universitario Rey Juan Carlos, Madrid, Spain
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Iñigo García Sanz
Iñigo García Sanz
Department of General & Digestive Surgery, Hospital Universitario de La Princesa, Madrid, Spain
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Mónica Recasens
Mónica Recasens
Department of Endocrinology & Nutrition, Institut Català de la Salut Girona, Girona, Spain
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Rebeca Barahona San Millan
Rebeca Barahona San Millan
Department of Endocrinology & Nutrition, Institut Català de la Salut Girona, Girona, Spain
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María José Picón César
María José Picón César
Department of Endocrinology & Nutrition, Hospital Universitario Virgen de la Victoria de Málaga, IBIMA Malaga, Spain CIBEROBN, Madrid, Spain
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Patricia Díaz Guardiola
Patricia Díaz Guardiola
Department of Endocrinology & Nutrition, Hospital Universitario Infanta Sofía, Madrid, Spain
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Carolina Perdomo
Carolina Perdomo
Department of Endocrinology & Nutrition, Clínica Universidad de Navarra, Pamplona, Spain
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Laura Manjón
Laura Manjón
Department of Endocrinology & Nutrition, Hospital Universitario Central de Asturias & Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Oviedo, Spain
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Rogelio García-Centeno
Rogelio García-Centeno
Department of Endocrinology & Nutrition, Hospital Universitario Gregorio Marañón, Madrid, Spain
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Juan Carlos Percovich
Juan Carlos Percovich
Department of Endocrinology & Nutrition, Hospital Universitario Gregorio Marañón, Madrid, Spain
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Ángel Rebollo Román
Ángel Rebollo Román
Department of Endocrinology & Nutrition, Hospital Reina Sofía, Córdoba, Spain
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Paola Gracia Gimeno
Paola Gracia Gimeno
Department of Endocrinology & Nutrition, Hospital Rollo Villanova, Zaragoza, Spain
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Cristina Robles Lázaro
Cristina Robles Lázaro
Department of Endocrinology & Nutrition, Complejo Universitario de Salamanca, Salamanca, Spain
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Manuel Morales
Manuel Morales
Biochemistry and Molecular Genetics Department-CDB, Hospital Clinic, IDIBAPS, CIBERehd, Barcelona, Spain
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María Calatayud
María Calatayud
Department of Endocrinology & Nutrition, Hospital Doce de Octubre, Madrid, Spain
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Simone Andree Furio Collao
Simone Andree Furio Collao
Department of Endocrinology & Nutrition, Hospital Doce de Octubre, Madrid, Spain
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Diego Meneses
Diego Meneses
Department of Endocrinology & Nutrition, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain
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Miguel Antonio Sampedro Nuñez
Miguel Antonio Sampedro Nuñez
Department of Endocrinology & Nutrition, Hospital Universitario La Princesa, Madrid, Spain
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Verónica Escudero Quesada
Verónica Escudero Quesada
Department of Nephrology, Hospital Universitario Doctor Peser, Valencia, Spain
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Elena Mena Ribas
Elena Mena Ribas
Department of Endocrinology & Nutrition, Hospital Universitario Son Espases, Islas Baleares, Spain
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Alicia Sanmartín Sánchez
Alicia Sanmartín Sánchez
Department of Endocrinology & Nutrition, Hospital Universitario Son Espases, Islas Baleares, Spain
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Cesar Gonzalvo Diaz
Cesar Gonzalvo Diaz
Department of Endocrinology & Nutrition, Hospital Universitario De Albacete, Albacete, Spain
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Cristina Lamas
Cristina Lamas
Department of Endocrinology & Nutrition, Hospital Universitario De Albacete, Albacete, Spain
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Raquel Guerrero-Vázquez
Raquel Guerrero-Vázquez
Department of Endocrinology & Nutrition, Hospital Virgen de la Macarena, Sevilla, Spain
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María del Castillo Tous
María del Castillo Tous
Department of Endocrinology & Nutrition, Hospital Virgen de la Macarena, Sevilla, Spain
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Joaquín Serrano
Joaquín Serrano
Department of Endocrinology & Nutrition, Hospital General Universitario de Alicante, Alicante, Spain
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Theodora Michalopoulou
Theodora Michalopoulou
Department of Endocrinology and Nutrition, Joan XXIII University Hospital, Tarragona, Spain
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Eva María Moya Mateo
Eva María Moya Mateo
Internal Medicine, Hospital Infanta Leonor de Vallecas, Madrid, Spain
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Felicia Hanzu
Felicia Hanzu
Department of Endocrinology & Nutrition, Hospital Clinic, IDIPAS, Barcelona, Spain
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, there is an increased risk of cardiometabolic comorbidities compared to the general population, probably related to the secretion of some adrenal steroids ( 29 ). In this regard, Wiebke Arlt et al. ( 4 ) performed mass spectrometry-based analysis of a
J Van Schaik
J Van Schaik
Division of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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M Burghard
M Burghard
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Exercise Physiology, Child Development & Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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Department of Exercise Physiology, Child Development & Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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M H Lequin
M H Lequin
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Radiology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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Department of Radiology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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E A van Maren
E A van Maren
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Radiology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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Department of Radiology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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A M van Dijk
A M van Dijk
Department of Dietetics, University Medical Center Utrecht, Utrecht, The Netherlands
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T Takken
T Takken
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Department of Exercise Physiology, Child Development & Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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Department of Exercise Physiology, Child Development & Exercise Center, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
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L B Rehorst-Kleinlugtenbelt
L B Rehorst-Kleinlugtenbelt
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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B Bakker
B Bakker
Division of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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L Meijer
L Meijer
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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E W Hoving
E W Hoving
Division of Neurosurgery, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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M Fiocco
M Fiocco
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Institute of Mathematics, Leiden University, Leiden, The Netherlands
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Institute of Mathematics, Leiden University, Leiden, The Netherlands
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A Y N Schouten-van Meeteren
A Y N Schouten-van Meeteren
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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W J E Tissing
W J E Tissing
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
Division of Pediatric Oncology, University Medical Centre Groningen, Groningen, The Netherlands
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Division of Pediatric Oncology, University Medical Centre Groningen, Groningen, The Netherlands
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H M van Santen
H M van Santen
Division of Pediatric Endocrinology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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Division of Pediatric Oncology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands
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13124308 ) 28 Oshima T Dupertuis YM Delsoglio M Graf S Heidegger CP Pichard C . In vitro validation of indirect calorimetry device developed for the ICALIC project against mass spectrometry . Clinical Nutrition ESPEN 2019 32 50 – 55
Mojca Zerjav Tansek
Mojca Zerjav Tansek
Department of Pediatric Endocrinology, Diabetes and Metabolic Diseases, University Children’s Hospital, UMC Ljubljana, Ljubljana, Slovenia
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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Ana Bertoncel
Ana Bertoncel
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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Brina Sebez
Brina Sebez
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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Janez Zibert
Janez Zibert
Centre for Health Informatics and Statistics, Faculty of Health Sciences, University of Ljubljana, Ljubljana, Slovenia
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Urh Groselj
Urh Groselj
Department of Pediatric Endocrinology, Diabetes and Metabolic Diseases, University Children’s Hospital, UMC Ljubljana, Ljubljana, Slovenia
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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Tadej Battelino
Tadej Battelino
Department of Pediatric Endocrinology, Diabetes and Metabolic Diseases, University Children’s Hospital, UMC Ljubljana, Ljubljana, Slovenia
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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Magdalena Avbelj Stefanija
Magdalena Avbelj Stefanija
Department of Pediatric Endocrinology, Diabetes and Metabolic Diseases, University Children’s Hospital, UMC Ljubljana, Ljubljana, Slovenia
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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height, body mass index (BMI), proportion of whole-body and abdominal fat), metabolic (mean and maximum serum Phe, mean serum Tyr, mean Phe/Tyr ratio) and nutritional (Phe intake tolerance as an indicator of natural protein intake, serum B12 vitamin, zinc
Nidan Qiao
Nidan Qiao
Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
Neuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
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Neuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
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adenoma Spectrum from histology GH+/GH−/non-tumor cells 1000:1000:1000 k means (k = 10), LDA Acc: 85.3% LOOCV s.d. : 10.5% Calligaris 2015 (11) 45 Pituitary adenoma Protein signature in mass spectrometry from histology ACTH
Eric Seidel
Eric Seidel
Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Nephrology and Medical Intensive Care, BCRT – Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany
Berlin Institute of Health (BIH), Berlin, Germany
Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
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Berlin Institute of Health (BIH), Berlin, Germany
Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
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Gudrun Walenda
Gudrun Walenda
Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
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Clemens Messerschmidt
Clemens Messerschmidt
Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Core Unit Bioinformatics, Berlin Institute of Health, Berlin, Germany
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Core Unit Bioinformatics, Berlin Institute of Health, Berlin, Germany
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Benedikt Obermayer
Benedikt Obermayer
Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Core Unit Bioinformatics, Berlin Institute of Health, Berlin, Germany
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Core Unit Bioinformatics, Berlin Institute of Health, Berlin, Germany
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Mirko Peitzsch
Mirko Peitzsch
Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
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Paal Wallace
Paal Wallace
Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
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Rohini Bahethi
Rohini Bahethi
Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
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Taekyeong Yoo
Taekyeong Yoo
Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea
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Murim Choi
Murim Choi
Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea
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Petra Schrade
Petra Schrade
Charité – Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institut für Vegetative Anatomie, Berlin, Germany
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Sebastian Bachmann
Sebastian Bachmann
Charité – Universitaetsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institut für Vegetative Anatomie, Berlin, Germany
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Gerhard Liebisch
Gerhard Liebisch
Institute of Clinical Chemistry and Laboratory Medicine, Regensburg University Hospital, Regensburg, Germany
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Graeme Eisenhofer
Graeme Eisenhofer
Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
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Dieter Beule
Dieter Beule
Core Unit Bioinformatics, Berlin Institute of Health, Berlin, Germany
Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany
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Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany
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Ute I Scholl
Ute I Scholl
Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Nephrology and Medical Intensive Care, BCRT – Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany
Berlin Institute of Health (BIH), Berlin, Germany
Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
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Berlin Institute of Health (BIH), Berlin, Germany
Department of Nephrology, School of Medicine, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
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and lysed in 1 mL water containing 0.1% sodium dodecyl sulfate (SDS, Biomol, Hamburg, Germany). Protein content was measured by BCA Protein Assay Kit (Pierce). Lipids were measured by electrospray ionization tandem mass spectrometry (ESI-MS/MS) and
