Pinaki Dutta
Pinaki Dutta
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Bhuvanesh Mahendran
Bhuvanesh Mahendran
Department of Endocrinology, Internal Medicine, Cardiology, Hematology, Histopathology, Gastroenterology, Neurosurgery, Pharmacology, Radiodiagnosis, 4th Floor, F Block, Post Graduate Institute of Medical Education and Research, Nehru Hospital, Chandigarh 160012, India
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K Shrinivas Reddy
K Shrinivas Reddy
Department of Endocrinology, Internal Medicine, Cardiology, Hematology, Histopathology, Gastroenterology, Neurosurgery, Pharmacology, Radiodiagnosis, 4th Floor, F Block, Post Graduate Institute of Medical Education and Research, Nehru Hospital, Chandigarh 160012, India
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Jasmina Ahluwalia
Jasmina Ahluwalia
Department of Endocrinology, Internal Medicine, Cardiology, Hematology, Histopathology, Gastroenterology, Neurosurgery, Pharmacology, Radiodiagnosis, 4th Floor, F Block, Post Graduate Institute of Medical Education and Research, Nehru Hospital, Chandigarh 160012, India
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Kim Vaiphei
Kim Vaiphei
Department of Endocrinology, Internal Medicine, Cardiology, Hematology, Histopathology, Gastroenterology, Neurosurgery, Pharmacology, Radiodiagnosis, 4th Floor, F Block, Post Graduate Institute of Medical Education and Research, Nehru Hospital, Chandigarh 160012, India
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Rakesh K Kochhar
Rakesh K Kochhar
Department of Endocrinology, Internal Medicine, Cardiology, Hematology, Histopathology, Gastroenterology, Neurosurgery, Pharmacology, Radiodiagnosis, 4th Floor, F Block, Post Graduate Institute of Medical Education and Research, Nehru Hospital, Chandigarh 160012, India
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Prakamya Gupta
Prakamya Gupta
Department of Endocrinology, Internal Medicine, Cardiology, Hematology, Histopathology, Gastroenterology, Neurosurgery, Pharmacology, Radiodiagnosis, 4th Floor, F Block, Post Graduate Institute of Medical Education and Research, Nehru Hospital, Chandigarh 160012, India
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Anand Srinivasan
Anand Srinivasan
Department of Endocrinology, Internal Medicine, Cardiology, Hematology, Histopathology, Gastroenterology, Neurosurgery, Pharmacology, Radiodiagnosis, 4th Floor, F Block, Post Graduate Institute of Medical Education and Research, Nehru Hospital, Chandigarh 160012, India
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Mahesh Prakash
Mahesh Prakash
Department of Endocrinology, Internal Medicine, Cardiology, Hematology, Histopathology, Gastroenterology, Neurosurgery, Pharmacology, Radiodiagnosis, 4th Floor, F Block, Post Graduate Institute of Medical Education and Research, Nehru Hospital, Chandigarh 160012, India
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Kanchan Kumar Mukherjee
Kanchan Kumar Mukherjee
Department of Endocrinology, Internal Medicine, Cardiology, Hematology, Histopathology, Gastroenterology, Neurosurgery, Pharmacology, Radiodiagnosis, 4th Floor, F Block, Post Graduate Institute of Medical Education and Research, Nehru Hospital, Chandigarh 160012, India
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hormones are intact or properly replaced (4, 5, 6) . In addition, GH replacement in these subjects has been shown to reverse many of the abnormalities (7) . There is a paucity of data on recombinant human GH (r-hGH) replacement therapy in acromegaly
Adriano N Cury
Adriano N Cury
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Verônica T Meira
Verônica T Meira
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Osmar Monte
Osmar Monte
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Marília Marone
Marília Marone
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Nilza M Scalissi
Nilza M Scalissi
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Cristiane Kochi
Cristiane Kochi
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Luís E P Calliari
Luís E P Calliari
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Carlos A Longui
Carlos A Longui
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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(before, during, and after RAI treatment), ATDs that were given before RAI therapy, hormone concentrations, and imaging, such as ultrasonography and thyroid scan radioiodine uptake. Other data that were related to RAI therapy were total iodine dose, number
Lauren R Cirrincione
Lauren R Cirrincione
Department of Pharmacy, University of Washington, Seattle, Washington, USA
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Bridgit O Crews
Bridgit O Crews
Department of Pathology and Laboratory Medicine, University of California Irvine, Orange, California, USA
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Jane A Dickerson
Jane A Dickerson
Department of Laboratories, Seattle Children's Hospital, Seattle, Washington, USA
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Matthew D Krasowski
Matthew D Krasowski
Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
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Jessica Rongitsch
Jessica Rongitsch
Internal Medicine, Capitol Hill Medical, Seattle, Washington, USA
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Katherine L Imborek
Katherine L Imborek
Department of Family Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
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Zil Goldstein
Zil Goldstein
Department of Medicine, Callen-Lorde Community Health Center, New York, New York, USA
CUNY Graduate School of Public Health and Health Policy, New York, New York, USA
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CUNY Graduate School of Public Health and Health Policy, New York, New York, USA
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Dina N Greene
Dina N Greene
Washington Kaiser Permanente, Renton, Washington, USA
Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA
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Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA
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Introduction Estradiol (17β-estradiol) is a natural sex steroid available in several exogenous preparations. The Endocrine Society recommended high-dose exogenous estradiol treatment as one part of feminizing hormone therapy for transgender
David S McLaren
David S McLaren
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospital NHS Trust, Leeds, UK
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Aarani Devi
Aarani Devi
Clinical Oncology, Leeds Cancer Centre, Leeds Teaching Hospital NHS Trust, Leeds, UK
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Nikolaos Kyriakakis
Nikolaos Kyriakakis
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospital NHS Trust, Leeds, UK
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Michelle Kwok-Williams
Michelle Kwok-Williams
Clinical Oncology, Leeds Cancer Centre, Leeds Teaching Hospital NHS Trust, Leeds, UK
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Robert D Murray
Robert D Murray
Department of Endocrinology, Leeds Centre for Diabetes & Endocrinology, Leeds Teaching Hospital NHS Trust, Leeds, UK
Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds, UK
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the use of proton therapy for the treatment of medulloblastoma has reduced the incidence of primary hypothyroidism, sex hormone deficiency, and the need for any hormone replacement therapy ( 51 , 52 ). One study reported that those treated with
Marcus Quinkler
Marcus Quinkler
Endocrinology in Charlottenburg, Berlin, Germany
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Bertil Ekman
Bertil Ekman
Departments of Endocrinology and Medical and Health Sciences, Linköping University, Linköping, Sweden
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Claudio Marelli
Claudio Marelli
Shire International GmbH, Zug, Switzerland
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Sharif Uddin
Sharif Uddin
Shire, Lexington, Massachusetts, USA
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Pierre Zelissen
Pierre Zelissen
Department of Internal Medicine and Endocrinology, University Medical Center Utrecht, Utrecht, the Netherlands
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Robert D Murray
Robert D Murray
Department of Endocrinology, Leeds Teaching Hospitals NHS Trust, St James’s University Hospital, Leeds, UK
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on behalf of the EU-AIR Investigators
on behalf of the EU-AIR Investigators
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cortisone, resulting in higher systemic availability of the active 11β-hydroxy form, prednisolone ( 12 ). Prednisolone is used in some patients with adrenal insufficiency (AI) as hormone replacement therapy. Advocates of prednisolone highlight that it
Kazhan Mollazadegan
Kazhan Mollazadegan
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Britt Skogseid
Britt Skogseid
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Johan Botling
Johan Botling
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
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Tobias Åkerström
Tobias Åkerström
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Barbro Eriksson
Barbro Eriksson
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Staffan Welin
Staffan Welin
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Anders Sundin
Anders Sundin
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
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Joakim Crona
Joakim Crona
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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demonstrated longer survival for panNET-G3 (range, 41–42 months) than for panNEC (range, 9–17 months) ( 8 , 9 ). Moreover, it has been hypothesized that panNET-G3 and panNEC respond differently to systemic therapy, with higher response rates on platinum
Hyun-Ah Kim
Hyun-Ah Kim
Department of Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Republic of Korea
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Jihye Choi
Jihye Choi
Department of Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Republic of Korea
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Chan Sub Park
Chan Sub Park
Department of Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Republic of Korea
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Min-Ki Seong
Min-Ki Seong
Department of Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Republic of Korea
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Sung-Eun Hong
Sung-Eun Hong
Department of Translational Research, Korea Institute of Radiological and Medical Sciences, Seoul, Republic of Korea
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Jae-Sung Kim
Jae-Sung Kim
Division of Basic Radiation Bioscience, Korea Institute of Radiological and Medical Sciences, Seoul, Republic of Korea
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In-Chul Park
In-Chul Park
Division of Basic Radiation Bioscience, Korea Institute of Radiological and Medical Sciences, Seoul, Republic of Korea
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Jin Kyung Lee
KIRAMS Radiation Biobank, Korea Institute of Radiological and Medical Sciences, Seoul, Republic of Korea
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Woo Chul Noh
Woo Chul Noh
Department of Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul, Republic of Korea
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the ASTRRA trial investigators
the ASTRRA trial investigators
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/m 2 ) q3w or four cycles of (doxorubicin 60 mg/m 2 and cyclophosphamide 600 mg/m 2 ) q3w followed by four cycles of (docetaxel 100 mg/m 2 ) q3w or six cycles of (doxorubicin 50 mg/m 2 and docetaxel 75 mg/m 2 ) q3w. For adjuvant hormone therapy, all
Nadia Sawicka-Gutaj
Nadia Sawicka-Gutaj
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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Ariadna Zybek-Kocik
Ariadna Zybek-Kocik
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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Michał Kloska
Michał Kloska
Lehigh Valley Health Network, Department of Medicine, Lehigh Valley Hospital – Cedar Crest, Allentown, USA
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Paulina Ziółkowska
Paulina Ziółkowska
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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Agata Czarnywojtek
Agata Czarnywojtek
Department of Pharmacology, Poznan University of Medical Sciences, Poznan, Poland
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Jerzy Sowiński
Jerzy Sowiński
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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Dorota Mańkowska-Wierzbicka
Dorota Mańkowska-Wierzbicka
Department of Gastroenterology, Internal Medicine, Metabolic Diseases and Dietetics, Poznan University of Medical Sciences, Poznan, Poland
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Marek Ruchała
Marek Ruchała
Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland
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total fat mass and insulin were mediators. P value <0.05 was considered statistically significant. Results Effects of therapy on hormonal and metabolic status Hormonal and metabolic parameters are compared in Table 1 . Table 1
Anita Hokken-Koelega
Anita Hokken-Koelega
Erasmus University Medical Centre, Rotterdam, The Netherlands
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Aart-Jan van der Lely
Aart-Jan van der Lely
Erasmus University Medical Centre, Rotterdam, The Netherlands
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Berthold Hauffa
Berthold Hauffa
University Children’s Hospital, Essen, Germany
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Gabriele Häusler
Gabriele Häusler
Medical University and General Hospital of Vienna, Vienna, Austria
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Gudmundur Johannsson
Gudmundur Johannsson
Sahlgrenska University Hospital, Göteborg, Sweden
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Mohamad Maghnie
Mohamad Maghnie
Istituto Giannina Gaslini, University of Genova, Genova, Italy
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Jesús Argente
Jesús Argente
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
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Jean DeSchepper
University Hospital Brussels, Brussels, Belgium
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Helena Gleeson
Helena Gleeson
Queen Elizabeth Hospital, Birmingham, UK
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John W Gregory
John W Gregory
Cardiff University School of Medicine, Cardiff, UK
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Charlotte Höybye
Charlotte Höybye
Department of Molecular Medicine and Surgery, Karolinska Institute and Department of Endocrinology, Metabolism and Diabetology, Karolinska University Hospital, Stockholm, Sweden
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Fahrettin Keleştimur
Fahrettin Keleştimur
Department of Endocrinology, School of Medicine, Erciyes University, Kayseri, Turkey
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Anton Luger
Anton Luger
Sahlgrenska University Hospital, Göteborg, Sweden
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Hermann L Müller
Hermann L Müller
Department of Pediatrics, Klinikum Oldenburg, Medical Campus University Oldenburg, Oldenburg, Germany
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Sebastian Neggers
Sebastian Neggers
University Children’s Hospital, Essen, Germany
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Vera Popovic-Brkic
Vera Popovic-Brkic
Belgrade University School of Medicine, Belgrade, Serbia
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Eleonora Porcu
Eleonora Porcu
University of Bologna, Bologna, Italy
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Lars Sävendahl
Lars Sävendahl
Department of Women’s and Children’s Health, Karolinska Institutet, and Pediatric Endocrinology Unit, Karolinska University Hospital, Stockholm, Sweden
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Stephen Shalet
Stephen Shalet
The Christie Hospital, Manchester, UK
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Bessie Spiliotis
Bessie Spiliotis
University of Patras School of Medicine, Patras, Greece
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Maithé Tauber
Maithé Tauber
Hôpital des Enfants, Toulouse, France
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hormone therapy, at supraphysiological doses, can improve adult height (gain of approximately 8 cm) with early treatment, preventing short stature in the majority of patients. Improvement in adult height is superior when administered earlier rather than
Ditte Sofie Dahl Sørensen
Ditte Sofie Dahl Sørensen
Department of Endocrinology and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Jesper Krogh
Jesper Krogh
Department of Endocrinology and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Åse Krogh Rasmussen
Åse Krogh Rasmussen
Department of Endocrinology and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Mikkel Andreassen
Mikkel Andreassen
Department of Endocrinology and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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-hydroxyprogesterone in the upper normal to mildly elevated normal range as a treatment goal ( 3 ), but currently, there is no consensus in relation to optimal disease markers or timing between replacement therapy and assessment of hormone levels. In the guideline by
