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Department of Developmental and Cell Biology, University of California, Irvine, California, USA
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Department of Pharmaceutical Sciences, University of California, Irvine, California, USA
Department of Biomedical Engineering, University of California, Irvine, California, USA
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.reprotox.2005.04.005 ) 49 Ornoy A Prenatal origin of obesity and their complications: gestational diabetes, maternal overweight and the paradoxical effects of fetal growth restriction and macrosomia . Reproductive Toxicology 2011 32 205 – 212
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are elevated in various metabolic diseases, such as obesity, insulin resistance, and type 2 diabetes mellitus ( 67 , 68 ). In addition, serum concentrations of FGF21, soluble α-klotho, and interleukin 6 are significantly higher in male smokers
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-β-HDL formation in type 2 diabetes mellitus patients ( 137 ). TH strongly induces ApoA1 gene and protein expression ( 138 ), thereby increasing cholesterol efflux from peripheral tissues to HDL in reverse cholesterol transport (RCT). Homocysteine levels
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School of Science and Health, Western Sydney University, Campbelltown, New South Wales, Australia
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The Florey Institute of Neuroscience and Mental Health, Parkville, Melbourne, Victoria, Australia
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Australian Institute for Musculoskeletal Science (AIMSS), College of Health and Biomedicine, Victoria University, Melbourne, Victoria, Australia
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School of Environment and Sciences, Griffith University, Nathan, Queensland, Australia
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consumed is unclear. Therefore GPR55 expression appears to vary depending on species, dietary intake and tissue type, and may also be a beneficial therapeutic target for obesity-related comorbidities such as type 2 diabetes mellitus. Further, O-1602
Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
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Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK
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Centre for Endocrinology, William Harvey Research Institute, Barts and The London Medical School, Queen Mary University of London, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, UK
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Department of Paediatric Endocrinology, Makarios Children's Hospital, Nicosia, Cyprus
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Sussex Community NHS Trust, Brighton, UK
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Developmental Endocrinology Research Group, University of Glasgow, Glasgow, UK
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The University of Dublin, Trinity College Dublin, Dublin, Republic of Ireland
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excessive weight gain, starting GH therapy may not be appropriate, especially in the presence of untreated or poorly managed OSA, poorly controlled type 2 diabetes mellitus (T2DM) and hypertension, and obesity-related complications. Once these complications
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. Patients affected by other endocrine diseases (e.g. central precocious puberty, congenital adrenal hyperplasia, hypothyroidism and type 1 diabetes mellitus), organic brain lesion and systemic diseases as well as patients taking drugs interfering with height
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.10.003 2 Wang Y Zhao X Zhao H Ding H Tan J Chen J Zhang R Azziz R Yang D. Risks for gestational diabetes mellitus and pregnancy-induced hypertension are increased in polycystic ovary syndrome . BioMed Research International 2013 2013 182582