Elin Kahlert
Elin Kahlert
Clinic of Gastroenterology and Endocrinology, University Medical Center Goettingen, Goettingen, Germany
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Martina Blaschke
Martina Blaschke
Clinic of Gastroenterology and Endocrinology, University Medical Center Goettingen, Goettingen, Germany
Endokrinologikum Goettingen, Goettingen, Germany
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Endokrinologikum Goettingen, Goettingen, Germany
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Knut Brockmann
Knut Brockmann
Interdisciplinary Pediatric Center for Children with Developmental Disabilities and Severe Chronic Disorders, University Medical Center Goettingen, Goettingen, Germany
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Clemens Freiberg
Clemens Freiberg
Interdisciplinary Pediatric Center for Children with Developmental Disabilities and Severe Chronic Disorders, University Medical Center Goettingen, Goettingen, Germany
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Onno E Janssen
Onno E Janssen
Endokrinologikum Hamburg, Hamburg, Germany
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Nikolaus Stahnke
Nikolaus Stahnke
Endokrinologikum Hamburg, Hamburg, Germany
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Domenika Strik
Domenika Strik
Endokrinologikum Berlin, Berlin, Germany
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Martin Merkel
Martin Merkel
Endokrinologikum Hannover, Hannover, Germany
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Alexander Mann
Alexander Mann
Endokrinologikum Frankfurt, Frankfurt/Main, Germany
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Klaus-Peter Liesenkötter
Klaus-Peter Liesenkötter
Endokrinologikum Berlin, Berlin, Germany
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Heide Siggelkow
Heide Siggelkow
Clinic of Gastroenterology and Endocrinology, University Medical Center Goettingen, Goettingen, Germany
Endokrinologikum Goettingen, Goettingen, Germany
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Endokrinologikum Goettingen, Goettingen, Germany
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comprises different questions concerning health, using healthcare and social and emotional factors. Furthermore, other tests and summary tools, transfer records, and a recommended approach for transitioning into adult practice are available on the Endocrine
Trine Holm Johannsen
Trine Holm Johannsen
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Jakob Albrethsen
Jakob Albrethsen
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Vassos Neocleous
Vassos Neocleous
The Cyprus Institute of Neurology and Genetics, Department of Molecular Genetics, Function and Therapy, Nicosia, Cyprus
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Federico Baronio
Federico Baronio
S. Orsola-Malpighi University Hospital, Department of Medical and Surgical Sciences, Bologna, Italy
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Martine Cools
Martine Cools
Department of Pediatrics, Division of Pediatric Endocrinology, Ghent University Hospital and Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium
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Lise Aksglaede
Lise Aksglaede
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Niels Jørgensen
Niels Jørgensen
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Peter Christiansen
Peter Christiansen
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Meropi Toumba
Meropi Toumba
The Cyprus Institute of Neurology and Genetics, Department of Molecular Genetics, Function and Therapy, Nicosia, Cyprus
Pediatric Endocrinology Clinic, Department of Pediatrics, Aretaeio Hospital, Nicosia, Cyprus
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Pediatric Endocrinology Clinic, Department of Pediatrics, Aretaeio Hospital, Nicosia, Cyprus
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Pavlos Fanis
Pavlos Fanis
The Cyprus Institute of Neurology and Genetics, Department of Molecular Genetics, Function and Therapy, Nicosia, Cyprus
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Marie Lindhardt Ljubicic
Marie Lindhardt Ljubicic
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Denmark
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, as such other factors may most likely add to their development ( 6 ). The biochemical assessment of gonadal capability in male patients with CAH includes measurements of gonadotropins and testicular and adrenal hormones. The elevated adrenal
Régis Coutant
Régis Coutant
Department of Pediatric Endocrinology and Diabetology, Reference Center for Rare Pituiatry Diseases, University Hospital of Angers, Angers, France
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Maithé Tauber
Maithé Tauber
Reference Center for the Prader-Willi syndrome and other rare obesities with feeding disorders (PRADORT), Children Hospital, CHU Toulouse, Toulouse, France
Pediatric team of the Clinical Investigation Center 9302/INSERM, Hospital of Children, Toulouse, France
Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), INSERM UMR1291 - CNRS UMR5051 - Université Toulouse III, Toulouse, France
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Pediatric team of the Clinical Investigation Center 9302/INSERM, Hospital of Children, Toulouse, France
Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), INSERM UMR1291 - CNRS UMR5051 - Université Toulouse III, Toulouse, France
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Béatrice Demaret
Béatrice Demaret
GRANDIR - French Growth Disorders Association, Asnières-sur-Seine, France
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Robin Henocque
Robin Henocque
Pfizer France, Paris France
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Yves Brault
Yves Brault
Pfizer France, Paris France
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François Montestruc
François Montestruc
eXYSTAT, Malakoff, France
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Olivier Chassany
Olivier Chassany
Health Economics Clinical Trial Unit (URC-ECO), Hospital of Hotel-Dieu, AP-HP, Paris, France
Patient-Reported Outcomes Unit (PROQOL), UMR 1123, University Paris Cité, INSERM, Paris, France
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Patient-Reported Outcomes Unit (PROQOL), UMR 1123, University Paris Cité, INSERM, Paris, France
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Michel Polak
Michel Polak
Hôpital Universitaire Necker Enfants Malades, Pediatric Endocrinology, Gynecology and Diabetology, Imagine Institute, INSERM U1163, Cochin Institute, INSERM U1016, Centre de référence des pathologies endocriniennes rares de la croissance et du développement, Université de Paris Cité, Paris, France
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the QOLITHOR Study Group
the QOLITHOR Study Group
the QOLITHOR Study Group
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of rhGH treatment together with other factors related to demographics and/or treatment. Material and methods Study design QOLITHOR is a non-interventional, multicenter, cross-sectional study conducted in 11 hospitals that belong to the
Mahmoud Al-Masri
Mahmoud Al-Masri
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Tawfiq Al-Shobaki
Tawfiq Al-Shobaki
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Hani Al-Najjar
Hani Al-Najjar
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Rafal Iskanderian
Rafal Iskanderian
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Enas Younis
Enas Younis
Department of Internal Medicine, Endocrine, King Hussein Cancer Center, Amman, Jordan
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Niveen Abdallah
Niveen Abdallah
Department of Cell Therapy & Applied Genomics, King Hussein Cancer Center, Amman, Jordan
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Abdelghani Tbakhi
Abdelghani Tbakhi
Department of Cell Therapy & Applied Genomics, King Hussein Cancer Center, Amman, Jordan
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Hussam Haddad
Hussam Haddad
Department of Pathology & Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan
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Mohammad Al-Masri
Mohammad Al-Masri
School of Medicine, University of Jordan, Amman, Jordan
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Zeinab Obeid
Zeinab Obeid
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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Awad Jarrar
Awad Jarrar
Department of Surgery, King Hussein Cancer Center, Amman, Jordan
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BRAF V600E, is the most common mutation, accounting for 60% of these mutations in thyroid cancer, with the highest incidence in PTC. BRAF is a constituent of the MAPK (ERK) signalling pathway, which activates transcription factors that are vital for
Clara Lundetoft Clausen
Clara Lundetoft Clausen
Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark
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Åse Krogh Rasmussen
Åse Krogh Rasmussen
Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital, Copenhagen, Denmark
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Trine Holm Johannsen
Trine Holm Johannsen
Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
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Linda Maria Hilsted
Linda Maria Hilsted
Department of Clinical Biochemistry, Copenhagen University Hospital, Copenhagen, Denmark
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Niels Erik Skakkebæk
Niels Erik Skakkebæk
Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
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Pal Bela Szecsi
Pal Bela Szecsi
Department of Clinical Biochemistry, Holbæk Hospital, Holbæk, Denmark
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Lise Pedersen
Lise Pedersen
Department of Clinical Biochemistry, Holbæk Hospital, Holbæk, Denmark
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Thomas Benfield
Thomas Benfield
Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Anders Juul
Anders Juul
Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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commonly, extrapulmonary systems are affected – including the endocrine system ( 1 ). Following case reports of thyroiditis associated with COVID-19, it has been hypothesized that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might induce
R Solomon-Zemler
R Solomon-Zemler
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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L Basel-Vanagaite
L Basel-Vanagaite
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Raphael Recanati Genetic Institute, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel
Felsenstein Medical Research Center, Petach Tikva, Israel
Pediatric Genetics, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Raphael Recanati Genetic Institute, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel
Felsenstein Medical Research Center, Petach Tikva, Israel
Pediatric Genetics, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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D Steier
D Steier
Day Hospitalization Department, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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S Yakar
S Yakar
David B. Kriser Dental Center, Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, New York, USA
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E Mel
E Mel
Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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M Phillip
M Phillip
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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L Bazak
L Bazak
Raphael Recanati Genetic Institute, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel
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D Bercovich
D Bercovich
Tel-Hai College, Tel-Hai, Israel
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H Werner
H Werner
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Shalom and VardaYoran Institute for Human Genome Research, Tel Aviv University, Tel Aviv, Israel
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Shalom and VardaYoran Institute for Human Genome Research, Tel Aviv University, Tel Aviv, Israel
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L de Vries
L de Vries
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Jesse Z. and Sara Lea Shafer Institute for Endocrinology and Diabetes, Schneider Children’s Medical Center of Israel, Petach Tikva, Israel
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Clinical Endocrinology and Metabolism 2003 88 5981 – 5988 . ( doi:10.1210/jc.2002-021080 ) 28 Jain S Golde DW Bailey R Geffner ME . Insulin-like growth factor-I resistance . Endocrine Reviews 1998 19 625 – 646 . 29 Mosthaf
Mohammed S Razzaque
Mohammed S Razzaque
Department of Pathology, Lake Erie College of Osteopathic Medicine, Erie, Pennsylvania, USA
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remarkable improvements in skeletal mineralization following vitamin D treatment, suggesting the possibility of a direct effect of vitamin D on the mineralization process ( Fig. 1 ) ( 7 ). Several factors, including phosphate-regulating fibroblast growth
Liselot Koelman
Liselot Koelman
Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany
Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
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Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
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Robin Reichmann
Robin Reichmann
Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
Department of Epidemiological Methods and Etiological Research, Leibniz Institute for Prevention Research and Epidemiology – BIPS, Bremen, Germany
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Department of Epidemiological Methods and Etiological Research, Leibniz Institute for Prevention Research and Epidemiology – BIPS, Bremen, Germany
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Claudia Börnhorst
Claudia Börnhorst
Department of Biometry and Data Management, Leibniz Institute for Prevention Research and Epidemiology – BIPS, Bremen, Germany
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Matthias B Schulze
Matthias B Schulze
Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany
Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
German Center for Diabetes Research (DZD), Neuherberg, Germany
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Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
German Center for Diabetes Research (DZD), Neuherberg, Germany
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Cornelia Weikert
Cornelia Weikert
Department of Food Safety, German Federal Institute for Risk Assessment, Berlin, Germany
Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany
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Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany
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Ronald Biemann
Ronald Biemann
Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany
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Berend Isermann
Berend Isermann
Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Leipzig, Germany
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Andreas Fritsche
Andreas Fritsche
Division of Endocrinology, Diabetology, Nephrology, Vascular Disease and Clinical Chemistry, Department of Internal Medicine, University of Tübingen, Tübingen, Germany
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Krasimira Aleksandrova
Krasimira Aleksandrova
Department of Epidemiological Methods and Etiological Research, Leibniz Institute for Prevention Research and Epidemiology – BIPS, Bremen, Germany
Faculty of Human and Health Sciences, University of Bremen, Bremen, Germany
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Faculty of Human and Health Sciences, University of Bremen, Bremen, Germany
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independent predictor of chronic subclinical inflammation. To guide strategies for precision prevention, better understanding of the factors that predispose elevated chemerin concentrations is highly warranted. The evidence, however, on the potential
Aaron Lerner
Aaron Lerner
B. Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
AESKU.KIPP Institute, Wendelsheim, Germany
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AESKU.KIPP Institute, Wendelsheim, Germany
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Patricia Jeremias
Patricia Jeremias
AESKU.KIPP Institute, Wendelsheim, Germany
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Torsten Matthias
Torsten Matthias
AESKU.KIPP Institute, Wendelsheim, Germany
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Introduction Hashimoto's thyroiditis Hashimoto’s thyroiditis (HT) is one of the most common autoimmune endocrine diseases, characterized by an autoimmune-mediated destruction of the thyroid gland. Initially considered a rarity, HT has now
Cristina Lamas
Cristina Lamas
Department of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
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Elena Navarro
Elena Navarro
Department of Endocrinology and Nutrition, Hospital Universitario Virgen del Rocío, Sevilla, Spain
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Anna Casterás
Anna Casterás
Department of Endocrinology and Nutrition, Hospital Vall d’Hebron, Barcelona, Spain
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Paloma Portillo
Paloma Portillo
Department of Endocrinology and Nutrition, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
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Victoria Alcázar
Victoria Alcázar
Department of Endocrinology and Nutrition, Hospital Universitario Severo Ochoa, Leganés, Spain
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María Calatayud
María Calatayud
Department of Endocrinology and Nutrition, Hospital Univeristario Doce de Octubre, Madrid, Spain
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Cristina Álvarez-Escolá
Cristina Álvarez-Escolá
Department of Endocrinology and Nutrition, Hospital Universitario La Paz, Madrid, Spain
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Julia Sastre
Julia Sastre
Department of Endocrinology and Nutrition, Complejo Hospitalario de Toledo, Hospital Virgen de la Salud, Toledo, Spain
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Evangelina Boix
Evangelina Boix
Department of Endocrinology and Nutrition, Hospital General Universitario de Elche, Elche, Spain
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Lluis Forga
Lluis Forga
Department of Endocrinology and Nutrition, Complejo Hospitalario de Navarra, Hospital de Navarra, Pamplona, Spain
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Almudena Vicente
Almudena Vicente
Department of Endocrinology and Nutrition, Complejo Hospitalario de Toledo, Hospital Virgen de la Salud, Toledo, Spain
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Josep Oriola
Josep Oriola
Biochemistry and Molecular Genetics Department, Hospital Clínic i Universitari de Barcelona, Barcelona, Spain
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Jordi Mesa
Jordi Mesa
Department of Endocrinology and Nutrition, Hospital Vall d’Hebron, Barcelona, Spain
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Nuria Valdés
Nuria Valdés
Department of Endocrinology and Nutrition, Hospital Universitario Central de Asturias, Oviedo, Spain
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Introduction Multiple endocrine neoplasia type 1 (MEN1) syndrome is a rare hereditary disease, with an estimated prevalence of 0.15–0.30 cases per 1000 in general population ( 1 , 2 ). Primary hyperparathyroidism (PHPT) is its most common
