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.e. increased risk of cardiovascular diseases, depression, lipid disorders, high serum prolactin concentration and negative impact on the haemostatic profile) ( 20 , 21 , 22 , 23 , 24 , 25 ). In particular, specific researches on cardiovascular risk among
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depression). Hypercalcemic crisis is defined as a serum Ca level >3.75 mmol/L. Secondary or tertiary hyperparathyroidism and multiple endocrine neoplasia were excluded. The study protocol was approved by the Clinical Research Ethics Committee of Qilu Hospital
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-related QoL. The EQ 5D-5L consists of two parts: a descriptive EQ-5D system with five dimensions (mobility, self-care, usual activities, pain/discomfort, anxiety/depression) each of which has patients rate aspects of their quality of life on a five
Cardiff University School of Medicine, Cardiff, UK
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experience was life-changing and they still struggle with work and relationships despite successful treatment. Many patients reported ongoing problems with depression and anxiety. 4: Patients initially felt intimidated by the tertiary multidisciplinary
Departament de Cirurgia, Universitat Autònoma de Barcelona, Barcelona, Spain
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rate of renal stones in comparison with the normal population. One year later, the same authors reported a significantly increased risk of hospitalization due to infections and depression/bipolar affective disorders ( 9 ). The PARADOX study also
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in depression: a dose-response study . Behavior Therapy 2016 47 527 – 537 . ( https://doi.org/10.1016/j.beth.2016.04.003 ) 10.1016/j.beth.2016.04.003 27423168 30 Dellas C Loskutoff DJ. Historical analysis of PAI-1
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892 – 897 . ( doi:10.1210/jc.2003-031235 ) 10.1210/jc.2003-031235 4 Spijker AT van Rossum EF. Glucocorticoid receptor polymorphisms in major depression. Focus on glucocorticoid sensitivity and neurocognitive functioning . Annals of the New York
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-workers reported dexamethasone-induced suppression of aldosterone in CAH ( 14 ). Holsboer and co-workers reported dexamethasone-induced suppression of DOC and corticosterone in female patients with endogenous depression ( 15 ). The endocrine mechanism underlying
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.1 Depression (%) 4.63 5.09 4.72 Cardiovascular disease (%) 3.72 4.24 4 Dallas steatosis index (DSI) −2.65 (1.39) −2.42 (1.42) −2.26 (1.4) Data are mean ( s.d. ) or percentages. DSI (Dallas steatosis index) is defined in
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depression). A relatively large number (4 out of 12) died because of infections. Table 4 Causes of death in 12 patients. Age Etiology Cause of death Underlying disease 43, female Postsurgical Cancer Cancer (Peutz