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R C S van Adrichem
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L J Hofland
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R A Feelders
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M C De Martino
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P M van Koetsveld
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C H J van Eijck Department of Internal Medicine, Department of Surgery, Department of Pathology, Sector of Endocrinology, Erasmus MC, ‘s Gravendijkwal 230, Room D-430, 3015 CE Rotterdam, The Netherlands

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R R de Krijger Department of Internal Medicine, Department of Surgery, Department of Pathology, Sector of Endocrinology, Erasmus MC, ‘s Gravendijkwal 230, Room D-430, 3015 CE Rotterdam, The Netherlands

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D M Sprij-Mooij
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J A M J L Janssen
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W W de Herder
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also found in tumors arising in the colon, breast, thyroid, prostate, and fibrous tissues (26, 27, 28, 29, 30, 31, 32) . Until present, these findings have not been reported for GEP NETs. As sCgA levels correlate well with tumor bulk, our data

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-13-0052
Volume/Issue:
Volume 2: Issue 4
Open access
Anne Jouinot Department of Medical Oncology, Cochin Hospital, Paris Descartes University, CARPEM, AP-HP, Paris, France
Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Descartes, Sorbonne Paris Cité, Paris, France

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Bernard Royer CHU Besançon, Clinical Pharmacology and Toxicology Dpt, Besançon cedex, France

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Etienne Chatelut Institut Claudius-Regaud, Université de Toulouse, INSERM, Centre de Recherches en Cancérologie de Toulouse, Toulouse, France

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Sotheara Moeung Institut Claudius-Regaud, Université de Toulouse, INSERM, Centre de Recherches en Cancérologie de Toulouse, Toulouse, France

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Guillaume Assié Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Descartes, Sorbonne Paris Cité, Paris, France
Department of Endocrinology, Center for Rare Adrenal Diseases, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Paris, France

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Audrey Thomas-Schoemann Department of Pharmacy, Cochin Hospital, Paris Descartes University, AP-HP, Paris, France
Pharmacokinetics and Pharmacochemistry Unit, Cochin Hospital, Paris Descartes University, AP-HP, Paris, France

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Jérôme Bertherat Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Descartes, Sorbonne Paris Cité, Paris, France
Department of Endocrinology, Center for Rare Adrenal Diseases, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Paris, France

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François Goldwasser Department of Medical Oncology, Cochin Hospital, Paris Descartes University, CARPEM, AP-HP, Paris, France

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Benoit Blanchet Pharmacokinetics and Pharmacochemistry Unit, Cochin Hospital, Paris Descartes University, AP-HP, Paris, France
UMR8638 CNRS, Pharmacy UFR, University of Paris Descartes, PRES sorbonne Paris Cité, Paris, France

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etoposide-like derivative of podophyllotoxin ( 13 ) – when patients received concomitant phenobarbital – which is a strong inducer of CYP3A4 and P-glycoprotein (P-gp) ( 14 ). Mitotane could induce both CYP3A4 and ABC transporters, notably breast resistance

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0428
Volume/Issue:
Volume 7: Issue 12
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Xiaohui Qi Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Ping He Shanghai Hospital Link Center, Shanghai Hospital Development Center, Shanghai, China

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Huayan Yao Computer Net Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Huanhuan Sun Wonders Information Co. Ltd, Shanghai, China

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Jiying Qi Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Min Cao Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Bin Cui Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Guang Ning Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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, colorectum, and breast ( 11 , 12 , 13 ). However, in a large number of studies on insulin and cancer, only one study has examined the relationship between insulin and BTC. But because only two cases of BTC occurred in 2156 insulin users, the study by

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-21-0546
Volume/Issue:
Volume 11: Issue 3
Open access
Anna Malczewska Department of Endocrinology and Neuroendocrine Tumours, Medical University of Silesia, Katowice, Poland

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Kjell Oberg Department of Endocrine Oncology, University Hospital, Uppsala, Sweden

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Beata Kos-Kudla Department of Endocrinology and Neuroendocrine Tumours, Medical University of Silesia, Katowice, Poland

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blood and can be used to provide a detailed assessment of the molecular biological status of an individual tumour in real-time ( 17 ). The implementation of such tools have proven to be of substantial clinical utility in breast, lung, colon and prostate

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0417
Volume/Issue:
Volume 10: Issue 1
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Kristian Almstrup Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Hanne Frederiksen Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Anna-Maria Andersson Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Anders Juul Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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, early age at menarche is associated with substantially higher risks for subsequent obesity, type 2 diabetes, cardiovascular disease as well as higher risks for breast cancer and all-cause mortality and late age at menarche is associated with asthma ( 3

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Research Article
DOI:
https://doi.org/10.1530/EC-20-0286
Volume/Issue:
Volume 9: Issue 8
Open access
Luis Eduardo Barbalho de Mello Genetic Bases of Thyroid Tumors Laboratory, Division of Genetics, Department of Morphology and Genetics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

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Thaise Nayane Ribeiro Carneiro Genetic Bases of Thyroid Tumors Laboratory, Division of Genetics, Department of Morphology and Genetics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Aline Neves Araujo Genetic Bases of Thyroid Tumors Laboratory, Division of Genetics, Department of Morphology and Genetics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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Camila Xavier Alves Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

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Pedro Alexandre Favoretto Galante Centro de Oncologia Molecular, Hospital Sírio-libanês, São Paulo, São Paulo, Brazil

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Vanessa Candiotti Buzatto Centro de Oncologia Molecular, Hospital Sírio-libanês, São Paulo, São Paulo, Brazil

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Maria das Graças de Almeida Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil
Department of Clinical and Toxicological Analyses, Natal, Rio Grande do Norte, Brazil

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Karina Marques Vermeulen-Serpa Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

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Sancha Helena de Lima Vale Department of Clinical and Toxicological Analyses, Natal, Rio Grande do Norte, Brazil
Department of Nutrition, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

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Fernando José de Pinto Paiva Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

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José Brandão-Neto Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

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Janete Maria Cerutti Genetic Bases of Thyroid Tumors Laboratory, Division of Genetics, Department of Morphology and Genetics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

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if the genetic basis of non-syndromic FNMTC has not been well established, the thyroid gland shows the highest familial relative risk compared to many other well-characterized cancers with Mendelian pattern of inheritance such as breast, colon and

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Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-21-0406
Volume/Issue:
Volume 11: Issue 1
Open access
Zhen-yu Song Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China

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Qiuming Yao Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

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Zhiyuan Zhuo Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China

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Zhe Ma Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China

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Gang Chen Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China

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cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium . Cancer 2015 121 1949 – 1956 . ( https://doi.org/10.1002/cncr.29320 ) 25 Buttigliero C Monagheddu C Petroni P Saini A Dogliotti L Ciccone G Berruti A

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Review Article
DOI:
https://doi.org/10.1530/EC-18-0283
Volume/Issue:
Volume 7: Issue 12
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T Szarvas Department of Urology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
Department of Urology, Semmelweis University, Budapest, Hungary

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B Jardin-Watelet Thermo Fisher Scientific Cezanne SAS, Clinical Diagnostics Division, Nimes, France

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N Bourgoin Thermo Fisher Scientific Cezanne SAS, Clinical Diagnostics Division, Nimes, France

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M J Hoffmann Department of Urology, Medical Faculty, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany

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P Nyirády Department of Urology, Semmelweis University, Budapest, Hungary

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C Oláh Department of Urology, Semmelweis University, Budapest, Hungary

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T Széll Department of Urology, Semmelweis University, Budapest, Hungary

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A Csizmarik Department of Urology, Semmelweis University, Budapest, Hungary

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B Hadaschik Department of Urology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

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H Reis Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

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monitoring of neuroendocrine tumors ( 5 ). In addition to neuroendocrine tumors, neuroendocrine activity and elevated CGA serum levels can also be detected in other tumors that are not derived from neuroendocrine tissues such as breast, prostate and ovarian

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0068
Volume/Issue:
Volume 8: Issue 5
Open access
Min Li Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China

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Ying Chen Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China

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Jingjing Jiang Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China

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Yan Lu Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China

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Zhiyi Song Department of Endocrinology and Metabolism, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Shengjie Zhang CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China

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Chao Sun CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China

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Hao Ying CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Shanghai, China

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Xiaofang Fan Department of Endocrinology and Metabolism, Minhang Branch, Zhongshan Hospital, Central Hospital of Minhang District, Shanghai Minhang Hospital, Fudan University, Shanghai, China

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Yuping Song Department of Endocrinology and Metabolism, Minhang Branch, Zhongshan Hospital, Central Hospital of Minhang District, Shanghai Minhang Hospital, Fudan University, Shanghai, China

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Jialin Yang Department of Endocrinology and Metabolism, Minhang Branch, Zhongshan Hospital, Central Hospital of Minhang District, Shanghai Minhang Hospital, Fudan University, Shanghai, China

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Lin Zhao Department of Endocrinology and Metabolism, Fudan Institute of Metabolic Diseases, Zhongshan Hospital, Fudan University, Shanghai, China

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-4827(02)00102-7 12648463 11 Dunn M Sinha P Campbell R Blackburn E Levinson N Rampaul R Bates T Humphreys S Gullick WJ . Co-expression of neuregulins 1, 2, 3 and 4 in human breast cancer . Journal of Pathology 2004 203 672 – 680 . ( https://doi.org/10.1002/path

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0175
Volume/Issue:
Volume 8: Issue 6
Open access
Katerina Saltiki Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece

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Elli Anagnostou Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece

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George Simeakis Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece

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Sofia Kouki Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece

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Anastasia Angelopoulou Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece

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Leda Sarika Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece

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Alexandra Papathoma Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece

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Maria Alevizaki Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece

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another 4/51 (7.8%) had other malignancies (lung, renal, unknown primary tumor, breast); thus, in 69% of the cases, the second malignancy was PTC. The PTC diagnosis in all patients was simultaneous to the MTC diagnosis, during the first surgery. These PTC

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0147
Volume/Issue:
Volume 6: Issue 8
Open access