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also found in tumors arising in the colon, breast, thyroid, prostate, and fibrous tissues (26, 27, 28, 29, 30, 31, 32) . Until present, these findings have not been reported for GEP NETs. As sCgA levels correlate well with tumor bulk, our data
Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Descartes, Sorbonne Paris Cité, Paris, France
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Department of Endocrinology, Center for Rare Adrenal Diseases, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Paris, France
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Pharmacokinetics and Pharmacochemistry Unit, Cochin Hospital, Paris Descartes University, AP-HP, Paris, France
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Department of Endocrinology, Center for Rare Adrenal Diseases, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Paris, France
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UMR8638 CNRS, Pharmacy UFR, University of Paris Descartes, PRES sorbonne Paris Cité, Paris, France
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etoposide-like derivative of podophyllotoxin ( 13 ) – when patients received concomitant phenobarbital – which is a strong inducer of CYP3A4 and P-glycoprotein (P-gp) ( 14 ). Mitotane could induce both CYP3A4 and ABC transporters, notably breast resistance
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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, colorectum, and breast ( 11 , 12 , 13 ). However, in a large number of studies on insulin and cancer, only one study has examined the relationship between insulin and BTC. But because only two cases of BTC occurred in 2156 insulin users, the study by
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blood and can be used to provide a detailed assessment of the molecular biological status of an individual tumour in real-time ( 17 ). The implementation of such tools have proven to be of substantial clinical utility in breast, lung, colon and prostate
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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, early age at menarche is associated with substantially higher risks for subsequent obesity, type 2 diabetes, cardiovascular disease as well as higher risks for breast cancer and all-cause mortality and late age at menarche is associated with asthma ( 3
Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil
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Department of Clinical and Toxicological Analyses, Natal, Rio Grande do Norte, Brazil
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if the genetic basis of non-syndromic FNMTC has not been well established, the thyroid gland shows the highest familial relative risk compared to many other well-characterized cancers with Mendelian pattern of inheritance such as breast, colon and
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cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium . Cancer 2015 121 1949 – 1956 . ( https://doi.org/10.1002/cncr.29320 ) 25 Buttigliero C Monagheddu C Petroni P Saini A Dogliotti L Ciccone G Berruti A
Department of Urology, Semmelweis University, Budapest, Hungary
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monitoring of neuroendocrine tumors ( 5 ). In addition to neuroendocrine tumors, neuroendocrine activity and elevated CGA serum levels can also be detected in other tumors that are not derived from neuroendocrine tissues such as breast, prostate and ovarian
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-4827(02)00102-7 12648463 11 Dunn M Sinha P Campbell R Blackburn E Levinson N Rampaul R Bates T Humphreys S Gullick WJ . Co-expression of neuregulins 1, 2, 3 and 4 in human breast cancer . Journal of Pathology 2004 203 672 – 680 . ( https://doi.org/10.1002/path
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another 4/51 (7.8%) had other malignancies (lung, renal, unknown primary tumor, breast); thus, in 69% of the cases, the second malignancy was PTC. The PTC diagnosis in all patients was simultaneous to the MTC diagnosis, during the first surgery. These PTC