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K L Gatford, G K Heinemann, S D Thompson, J V Zhang, S Buckberry, J A Owens, G A Dekker, C T Roberts and on behalf of the SCOPE Consortium

pregnancy on bone density and bone turnover . Journal of Bone and Mineral Research 2000 15 129 – 137 . ( doi:10.1359/jbmr.2000.15.1.129 ). 13 Black AJ Topping J Durham B Farquharson RG Fraser WD . A detailed assessment of alterations in

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Lijuan Yuan, Xihui Chen, Ziyu Liu, Dan Wu, Jianguo Lu, Guoqiang Bao, Sijia Zhang, Lifeng Wang and Yuanming Wu

Hospital and Lanzhou Military Region Hospital. The 1, 2, 3, 4 families were all from northwest areas in China (Ningxia, Erdos, Lanzhou, and Xi’an, respectively). All patients were diagnosed by clinical manifestation and finger and long bone X ray. There was

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Kennett Sprogøe, Eva Mortensen, David B Karpf and Jonathan A Leff

Introduction Following secretion from the anterior pituitary, human growth hormone (GH) is transported throughout the body, exerting its effects via GH receptors on virtually every cell of the body. In addition to muscle and bone growth, GH is

Open access

Tatiana V Novoselova, Peter J King, Leonardo Guasti, Louise A Metherell, Adrian J L Clark and Li F Chan

advanced or dissociated bone age ( 23 ). The mechanism for this phenomenon remains unclear but is not due to the insulin-like growth factor 1–growth hormone axis as this is normal ( 20 ). One potential explanation is that the phenotype is due to high plasma

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Kathrin Zopf, Kathrin R Frey, Tina Kienitz, Manfred Ventz, Britta Bauer and Marcus Quinkler

). Recently, we could show that bone mineral density in patients with adrenal insufficiency is at least partially dependent on the Bcl I polymorphism of the GR ( 20 ). This triggers the question if intercurrent illnesses, their duration and the occurrence of

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Joana Simões-Pereira, Daniel Macedo and Maria João Bugalho

metastases (encephalic parenchyma involvement and/or leptomeningeal carcinomatosis) from this tumor were considered as inclusion criteria. Patients with coexisting malignant neoplasms and/or CNS involvement due to skull bone metastases were excluded from

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June Young Choi, Jin Wook Yi, Jun Hyup Lee, Ra-Yeong Song, Hyeongwon Yu, Hyungju Kwon, Young Jun Chai, Su-jin Kim and Kyu Eun Lee

(alive) Dead 1.217 0.729 Total 40 patients showed recurrence after surgery. 21 patients had locoregional recurrence including central and lateral neck nodes, whereas 15 patients had distant recurrence such as bone, lung, etc. There

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Aleksandra Krygier, Ewelina Szczepanek-Parulska, Dorota Filipowicz and Marek Ruchała

). The mechanism responsible for anaemia in the course of hyperthyroidism is not well understood. Due to accelerated metabolism and thus higher oxygen requirements, bone marrow presents erythroid hyperplasia, where ineffective erythropoiesis occurs

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Sandra R Dahl, Ingrid Nermoen, Ingeborg Brønstad, Eystein S Husebye, Kristian Løvås and Per M Thorsby

puberty with accelerated bone age will ensue. The prevalence of 21OHD shows large ethnic and geographic differences; the worldwide incidence is approximately 1/15,000 based on newborn screening ( 3 ). The aim of the medical treatment is to provide

Open access

Göran Oleröd, Lillemor Mattsson Hultén, Ola Hammarsten and Eva Klingberg

Introduction Vitamin D is essential for the calcium homeostasis and bone health and also of importance for the immune function, muscles and the cardiovascular system. Vitamin D3 is mainly produced in the skin after ultraviolet radiation, but