Yanfei Chen
Yanfei Chen
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Mei Li
Mei Li
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Binrong Liao
Binrong Liao
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Jingzi Zhong
Jingzi Zhong
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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Dan Lan
Dan Lan
Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China
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factors, including leptin, adiponectin, ghrelin, and insulin, which are known to have an impact on puberty initiation ( 7 ). It is known that obese boys and girls tend to undergo an earlier timing of puberty ( 8 ). A certain threshold of body fat stores (i
Stephanie E Baldeweg
Stephanie E Baldeweg
Department of Endocrinology, University College Hospital, London, UK
National Hospital for Neurology and Neurosurgery, London, UK
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National Hospital for Neurology and Neurosurgery, London, UK
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Mark Vanderpump
Mark Vanderpump
Physicians’ Clinic, London, UK
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Will Drake
Will Drake
Department of Endocrinology, St Bartholomew’s Hospital, London, UK
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Narendra Reddy
Narendra Reddy
Endocrinology/General Medicine, University Hospitals Coventry and Warwickshire NHS Trust, University of Warwick, Coventry, UK
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Andrew Markey
Andrew Markey
The Lister Hospital, London, UK
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Gordon T Plant
Gordon T Plant
Department of Endocrinology, University College Hospital, London, UK
National Hospital for Neurology and Neurosurgery, London, UK
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National Hospital for Neurology and Neurosurgery, London, UK
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Michael Powell
Michael Powell
National Hospital for Neurology and Neurosurgery, London, UK
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Saurabh Sinha
Saurabh Sinha
Royal Hallamshire Hospital, Sheffield, UK
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John Wass
John Wass
Department of Endocrinology, Oxford Centre for Diabetes Endocrinology and Metabolism, The Churchill, Oxford University, Oxford, UK
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the Society for Endocrinology Clinical Committee
the Society for Endocrinology Clinical Committee
The Society for Endocrinology, 22 Apex Court, Woodlands, Bradley Stoke, Bristol, UK
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potentially lifesaving in these patients In adults, hydrocortisone 100 mg i.m. bolus followed by 50–100 mg six hourly by intramuscular injection or 100–200 mg as an intravenous bolus followed by 2–4 mg per hour by continuous i.v. infusion can be used
Yuanyuan Li
Yuanyuan Li
Department of Endocrinology, Inner Mongolia People’s Hospital, Hohhot, Inner Mongolia, China
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Dongmei Li
Dongmei Li
Department of Endocrinology, Inner Mongolia People’s Hospital, Hohhot, Inner Mongolia, China
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Xingbo Cheng
Xingbo Cheng
Department of Endocrinology, The First Affiliated Hospital of Soochow University, Suzhou, China
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anabolic processes are prioritized, allowing for the storage of more fat and energy. In late pregnancy, the i.v. glucose tolerance test shows that insulin in the first and second secretory phases increases three-fold after stimulation possibly to compensate
Patrizia Bruzzi
Patrizia Bruzzi
Department of Medical and Surgical Sciences of Mothers, Children and Adults, University of Modena & Reggio Emilia, Paediatric Unit, Modena, Italy
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Silvia Vannelli
Silvia Vannelli
Pediatric Endocrinologic Unit, Regina Margherita Children’s Hospital, Turin, Italy
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Emanuela Scarano
Emanuela Scarano
Unit of Pediatrics, Department of Medical and Surgical Sciences, Policlinico St. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy
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Natascia Di Iorgi
Natascia Di Iorgi
Department of Pediatrics, IRCCS Istituto Giannina Gaslini, University of Genova, Genova, Italy
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Maria Parpagnoli
Maria Parpagnoli
Anna Meyer Children's University Hospital, Florence, Italy
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MariaCarolina Salerno
MariaCarolina Salerno
Department of Translational Medicine, University Federico II, Naples, Italy
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Marco Pitea
Marco Pitea
Pediatric Unit, Ospedale San Raffaele, Milano, Italy
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Maria Elisabeth Street
Maria Elisabeth Street
Division of Paediatric Endocrinology and Diabetology, Paediatrics, Department of Mother and Child-AUSL of Reggio Emilia-IRCCS, Reggio Emilia, Italy
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Andrea Secco
Andrea Secco
Pediatric Unit, Azienda ospedaliero Nazionale SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
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Adolfo Andrea Trettene
Adolfo Andrea Trettene
Pediatric Unit, ASST Sette Laghi, Varese, Italy
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Malgorzata Wasniewska
Malgorzata Wasniewska
Department of Human Pathology in Adulthood and Childhood, University of Messina, Messina, Italy
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Nicola Corciulo
Nicola Corciulo
Pediatric Unit, P.O. Gallipoli, ASL Lecce, Italy
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Gianluca Tornese
Gianluca Tornese
Institute for maternal and child health IRCCS Burlo Garofalo, Trieste, Italy
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Maria Felicia Faienza
Maria Felicia Faienza
DAI Scienze Chirurgiche e Pediatriche, Ospedale Pediatrico Giovanni XXIII, Bari, Italy
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Maurizio Delvecchio
Maurizio Delvecchio
U.O. Malattie Metaboliche e Genetiche e Diabetologia, Ospedale Pediatrico Giovanni XXIII, Bari, Italy
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Simona Filomena Madeo
Simona Filomena Madeo
Department of Medical and Surgical Sciences of Mothers, Children and Adults, University of Modena & Reggio Emilia, Paediatric Unit, Modena, Italy
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Lorenzo Iughetti
Lorenzo Iughetti
Department of Medical and Surgical Sciences of Mothers, Children and Adults, University of Modena & Reggio Emilia, Paediatric Unit, Modena, Italy
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_2021_modifica_nota_39.pdf ) 25 Tirosh A Toledano Y Masri-Iraqi H Eizenberg Y Tzvetov G Hirsch D Benbassat C Robenshtok E & Shimon I . IGF-I levels reflect hypopituitarism severity in adults with pituitary dysfunction . Pituitary 2016 19
Esben Thyssen Vestergaard
Esben Thyssen Vestergaard
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Morten B Krag
Morten B Krag
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Morten M Poulsen
Morten M Poulsen
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Steen B Pedersen
Steen B Pedersen
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Niels Moller
Niels Moller
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Jens Otto Lunde Jorgensen
Jens Otto Lunde Jorgensen
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Niels Jessen
Niels Jessen
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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Medical Research Laboratories, Department of Endocrinology and Diabetes, Department of Pediatrics, Department of Endocrinology and Diabetes, Institute of Clinical Medicine, Aarhus University, Norrebrogade 44, DK-8000 Aarhus C, Denmark
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i.v. ghrelin infusion; to study direct effects of GH, healthy subjects were treated with GH in a period of 8 days. Insulin sensitivity assessed by the euglycemic clamp technique and measurements of serum RBP4 levels were recorded. Materials and
Xi Wang
Xi Wang
Department of Obstetrics and Gynaecology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
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Qi Yu
Qi Yu
Department of Obstetrics and Gynaecology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China
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-treatment and on-treatment safety and efficacy measures were evaluated using paired t -tests, Wilcoxon matched-pairs and Wilcoxon signed-rank tests. The data were analysed using the R software (R i386 3.4.3.lnk, Bell Laboratory, NJ, USA), and figures were
Jordyn Silverstein
Jordyn Silverstein
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
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Wesley Kidder
Wesley Kidder
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Susan Fisher
Susan Fisher
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California, USA
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Thomas A Hope
Thomas A Hope
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
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Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
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Samantha Maisel
Samantha Maisel
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
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Dianna Ng
Dianna Ng
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Department of Pathology, University of California, San Francisco, California, USA
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Department of Pathology, University of California, San Francisco, California, USA
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Jessica Van Ziffle
Jessica Van Ziffle
Department of Pathology, University of California, San Francisco, California, USA
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Chloe E Atreya
Chloe E Atreya
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Katherine Van Loon
Katherine Van Loon
Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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normal colon tissue ( 38 ). The IGF family has been shown to have mitogenic and anti-apoptotic effects on proliferation in various epithelial cells, including the colon ( 39 ). In addition, high blood levels of IGF-I and IGF-II have been shown to be
Masatada Watanabe
Masatada Watanabe
Laboratory of Tissue Regeneration, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo, Japan
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Shuji Ohno
Shuji Ohno
Division of Research for Pharmacy Students Education, Hoshi University, Shinagawa, Tokyo, Japan
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Hiroshi Wachi
Hiroshi Wachi
Laboratory of Tissue Regeneration, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo, Japan
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), a cAMP analog, insulin and IGF-I in the presence of serum ( 8 ). During expression of the CYP19A1 gene in human fibroblasts, of the multiple exons I in the human CYP19A1 gene ( Fig. 1A ), exon I.4 (exon 1b) was mainly selected as the 5′-UTR of
Alberto Battezzati
Alberto Battezzati
International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy
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Andrea Foppiani
Andrea Foppiani
International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy
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Gianfranco Alicandro
Gianfranco Alicandro
Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
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Arianna Bisogno
Arianna Bisogno
Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
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Arianna Biffi
Arianna Biffi
Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
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Giorgio Bedogni
Giorgio Bedogni
Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy
Internal Medicine, S. Maria delle Croci Hospital, AUSL Romagna, Ravenna, Italy
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Internal Medicine, S. Maria delle Croci Hospital, AUSL Romagna, Ravenna, Italy
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Simona Bertoli
Simona Bertoli
International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy
Istituto Auxologico Italiano, IRCCS, Obesity Unit - Laboratory of Nutrition and Obesity Research, Department of Endocrine and Metabolic Diseases, Milan, Italy
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Istituto Auxologico Italiano, IRCCS, Obesity Unit - Laboratory of Nutrition and Obesity Research, Department of Endocrine and Metabolic Diseases, Milan, Italy
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Giulia De Carlo
Giulia De Carlo
International Center for the Assessment of Nutritional Status, DeFENS, University of Milan, Milan, Italy
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Erica Nazzari
Erica Nazzari
Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
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Carla Colombo
Carla Colombo
Cystic Fibrosis Center, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca’ Granda, Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
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.1210/jcem.85.12.7017 ) 37 Gahete MD Córdoba-Chacón J Lin Q Brüning JC Kahn CR Castaño JP Christian H Luque RM Kineman RD . Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms . Endocrinology
Ekaterina Koledova
Ekaterina Koledova
Biopharma Global Medical Affairs, General Medicine and Endocrinology, Merck KGaA, Darmstadt, Germany
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George Stoyanov
George Stoyanov
Biopharma Global Medical Affairs, General Medicine and Endocrinology, Merck KGaA, Darmstadt, Germany
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Leroy Ovbude
Leroy Ovbude
Business & Decision Life Sciences, Brussels, Woluwe-Saint-Lambert, Belgium
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Peter S W Davies
Peter S W Davies
Children’s Nutrition Research Centre, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia
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Murillo M Salinas I Granada ML Martinez M Puig-Domingo M Andreu A Bel J . Variability in adherence to rhGH treatment: socioeconomic causes and effect on children’s growth . Growth Hormone and IGF Research 2016 26 32 – 35 . ( https
