Zhenzhen Wang
Zhenzhen Wang
Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China
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Xiangying Zhu
Xiangying Zhu
Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China
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Xiaohui Yu
Xiaohui Yu
Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China
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Haixia Guan
Haixia Guan
Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China
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Lei Zhao
Lei Zhao
Department of Ultrasonography, The First Affiliated Hospital of China Medical University, Shenyang, China
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Yixia Zhang
Yixia Zhang
Department of Ultrasonography, The First Affiliated Hospital of China Medical University, Shenyang, China
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Yuge Li
Yuge Li
Department of Ultrasonography, The First Affiliated Hospital of China Medical University, Shenyang, China
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Liang Sang
Liang Sang
Department of Ultrasonography, The First Affiliated Hospital of China Medical University, Shenyang, China
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Yuchen Han
Yuchen Han
Department of Pathology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China
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Yushu Li
Yushu Li
Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China
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Zhongyan Shan
Zhongyan Shan
Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China
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Weiping Teng
Weiping Teng
Department of Endocrinology and Metabolism, Institute of Endocrinology, The First Affiliated Hospital of China Medical University, Shenyang, China
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Introduction Nodular thyroid disease is common in endocrine practice. In iodine-sufficient areas, the thyroid nodule detection rate, as determined by palpation, is 5% in women and 1% in men ( 1 , 2 ), whereas the detection rate, as determined
Fei Wu
Fei Wu
Department of Nuclear Medicine, Yancheng City No. 1 People’s Hospital, Yancheng, China
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Chaoming Mao
Chaoming Mao
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Xiao Mou
Xiao Mou
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Chengcheng Xu
Chengcheng Xu
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Tingting Zheng
Tingting Zheng
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Ling Bu
Ling Bu
Department of Clinical Medicine, Jiangsu Health Vocational College, Nanjing, China
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Xuan Luo
Xuan Luo
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Qingyan Lu
Qingyan Lu
Department of Laboratory Medicine, Xuzhou Central Hospital, Xuzhou, China
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Xuefeng Wang
Xuefeng Wang
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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’disease and Hashimoto’s thyroiditis . Endokrynologia Pediatryczna 2011 34 37 – 48 . ( https://doi.org/10.3109/08916934.2014.910767 ) 3 Weetman AP Cellular immune responses in autoimmune thyroid disease . Clinical Endocrinology 2004 61 405 – 413 . ( https
Xiaoli Jin
Xiaoli Jin
Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China
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Jiankang Shen
Jiankang Shen
Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China
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Tao Liu
Tao Liu
Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China
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Ru Zhou
Ru Zhou
Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China
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Xunbo Huang
Xunbo Huang
Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China
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Tianxiang Wang
Tianxiang Wang
Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China
Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Weize Wu
Weize Wu
Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China
Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Mingliang Wang
Mingliang Wang
Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China
Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Rongli Xie
Rongli Xie
Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China
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Jianming Yuan
Jianming Yuan
Department of General Surgery, Ruijin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China
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and methods This study was approved by the Ethics Committee of our hospital. All the procedures were performed in accordance with the principles of the Declaration of Helsinki. Patients Patients diagnosed with thyroid disease and who underwent
T P McVeigh
T P McVeigh
Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, NUI Galway, Galway, Ireland
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R J Mulligan
R J Mulligan
Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, NUI Galway, Galway, Ireland
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U M McVeigh
U M McVeigh
Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, NUI Galway, Galway, Ireland
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P W Owens
P W Owens
Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, NUI Galway, Galway, Ireland
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N Miller
N Miller
Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, NUI Galway, Galway, Ireland
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M Bell
M Bell
Department of Endocrinology, School of Medicine, NUI Galway, Galway, Ireland
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F Sebag
F Sebag
Department of Endocrine Surgery Centre hospitalo-universitaire de La Conception, Assistance Publique Hôpitaux de Marseille, Marseille, France
Aix-Marseille Université, Faculté de Médecine, Marseille, France
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Aix-Marseille Université, Faculté de Médecine, Marseille, France
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C Guerin
C Guerin
Department of Endocrine Surgery Centre hospitalo-universitaire de La Conception, Assistance Publique Hôpitaux de Marseille, Marseille, France
Aix-Marseille Université, Faculté de Médecine, Marseille, France
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Aix-Marseille Université, Faculté de Médecine, Marseille, France
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D S Quill
D S Quill
Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, NUI Galway, Galway, Ireland
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J B Weidhaas
J B Weidhaas
David Geffen School of Medicine, University of California, Los Angeles, USA
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M J Kerin
M J Kerin
Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, NUI Galway, Galway, Ireland
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A J Lowery
A J Lowery
Discipline of Surgery, Lambe Institute for Translational Research, School of Medicine, NUI Galway, Galway, Ireland
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predispose to both types of malignancy as part of the PTEN hamartoma tumour syndrome ( 6 ). A relationship between BC and benign thyroid disease has also been hypothesised ( 7 ), given the common iodine transport mechanism ( 8 , 9 ), prevalence of anti
Qiankai Jin
Qiankai Jin
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Guoqing Huang
Guoqing Huang
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Xiaoqing Tian
Xiaoqing Tian
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Yimeng Shu
Yimeng Shu
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Ximisinuer Tusongtuoheti
Ximisinuer Tusongtuoheti
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
School of Medicine, Ningbo University, Ningbo, China
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School of Medicine, Ningbo University, Ningbo, China
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Yushan Mao
Yushan Mao
Department of Endocrinology, The Affiliated Hospital of Medical School, Ningbo University, Ningbo, China
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who were diagnosed with thyroid disease; (iii) employees who have taken glucocorticoids and amiodarone within the recent month; (iv) employees who refused or did not undergo biochemistry and thyroid function tests; (v) employees who had abnormal TSH
Eugenie S Lim
Eugenie S Lim
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Shanty G Shah
Shanty G Shah
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Mona Waterhouse
Mona Waterhouse
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Scott Akker
Scott Akker
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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William Drake
William Drake
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Nick Plowman
Nick Plowman
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Daniel M Berney
Daniel M Berney
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Polly Richards
Polly Richards
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Ashok Adams
Ashok Adams
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Ewa Nowosinska
Ewa Nowosinska
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Carmel Brennan
Carmel Brennan
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Maralyn Druce
Maralyn Druce
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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antibodies, and conversely, patients with positive TPO antibodies may never develop thyroid disease ( 20 ). Antibody reactions in autoimmune thyroiditis targeted towards thyroid-specific antigens may hasten thyroid destruction ( 21 ). It has also been
Peter D Mark
Peter D Mark
Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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Mikkel Andreassen
Mikkel Andreassen
Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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Claus L Petersen
Claus L Petersen
Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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Andreas Kjaer
Andreas Kjaer
Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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Jens Faber
Jens Faber
Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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in the elderly and can be divided into either endogenous causes most often due to autonomous nodular thyroid disease, or exogenous causes due to suppressive therapy with thyroid hormones in thyroid cancer or goiter or overtreatment of hypothyroidism
Anna Olsson-Brown
Anna Olsson-Brown
Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
The Clatterbridge Cancer Centre, Wirral, UK
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The Clatterbridge Cancer Centre, Wirral, UK
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Rosemary Lord
Rosemary Lord
The Clatterbridge Cancer Centre, Wirral, UK
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Joseph Sacco
Joseph Sacco
The Clatterbridge Cancer Centre, Wirral, UK
Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK
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Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK
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Jonathan Wagg
Jonathan Wagg
Roche Innovation Center, Basel, Switzerland
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Mark Coles
Mark Coles
Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK
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Munir Pirmohamed
Munir Pirmohamed
Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK
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dysfunction. Clinical examination did not reveal any signs of thyroid disease including goitre, exophthalmos, pretibial myxoedema or proximal myopathy. The hyperthyroid phase in HH spontaneously terminated in all patients without pharmacological intervention
Leqi He
Leqi He
Department of Clinical Laboratory Medicine, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Xiaoying Li
Xiaoying Li
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Zaoping Chen
Zaoping Chen
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Wei Wang
Wei Wang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Kai Wang
Kai Wang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Xinmei Huang
Xinmei Huang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Qian Yang
Qian Yang
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Wencai Ke
Wencai Ke
Department of Clinical Laboratory Medicine, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Jun Liu
Jun Liu
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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Bingbing Zha
Bingbing Zha
Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China
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criteria: (i) miscarriage risk, (ii) iron deficiency, (iii) history of thyroid disease or other chronic diseases (e.g. autoimmune diseases, hypertension, cancer, and diabetes), and (iv) use of oral drugs affecting thyroid function (e.g. traditional Chinese
Alessandro Brancatella
Alessandro Brancatella
Endocrine Unit 1, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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Claudio Marcocci
Claudio Marcocci
Endocrine Unit 2, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy
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(59) USA Cross-sectional 160 postmenopausal women with thyroid disease: • 44 goiter • 11 cancer • 41 hypothyroidism • 32 hyperthyroidism (treated) • 32 nodules N.A. 140 women without thyroid disease Questionnaire No difference
