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metabolic syndrome, with visceral obesity, insulin resistance, endothelial dysfunction, increased sympathetic activity, and a pro-inflammatory profile (3, 4, 5) . Although GH replacement therapy has been shown to reduce the risk profile (6) , it is still
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. The primary NETs were originating from the small intestine, pancreas, stomach, lung, or had an unknown origin. Patients were eligible for the study if they were medical treatment naive, were not obese, and had neither metabolic syndrome nor diabetes
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Journal of Endocrinology 2013 2013 590569 . ( https://doi.org/10.1155/2013/590569 ) 12 Maric C Hall JE . Obesity, metabolic syndrome and diabetic nephropathy . Contributions to Nephrology 2011 170 28 – 35 . ( https://doi.org/10
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physiological function ( 6 , 7 ). Recent studies have shown that abnormal MAMs’ structure and function are closely related to the occurrence and development of many clinical diseases, such as metabolic syndrome ( 8 ), cancer ( 9 ), and neurodegenerative
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, these women undergo anthropometric (weight, height, and body mass index (BMI)), metabolic (blood tests for lipid profile, fasting glucose, and metabolic syndrome score), and dermatologic (modified Ferriman–Gallwey score) assessments as part of their
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tended to have significantly lower BMI, WHR and TG than those in negative group, suggesting that GADA-positive participants seemed to be leaner and to have less abdominal obesity. T2DM has always been considered as a chronic metabolic syndrome with higher
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clinical practice-insulin resistance indices. Diabetes and Metabolic Syndrome 2016 10 ( Supplement 1 ) S120 – S125 . ( https://doi.org/10.1016/j.dsx.2015.10.007 ) 10.1016/j.dsx.2015.10.007) 8 McAuley KA Williams SM Mann JI Walker RJ Lewis
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Medical Research Laboratories, Departments of Clinical Biochemistry, Molecular Medicine, Department of Clinical Genetics, Department of Endocrinology and Internal Medicine, Clinical Institute, Aarhus University Hospital, Nørrebrogade 44, DK-8000 Aarhus C, Denmark
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-hydroxysteroid dehydrogenase type 1 (11β-HSD1) in adipose tissue and higher levels have indeed been associated also with the metabolic syndrome (49) found prevalent in both KS and TS (12, 41) . Thus at least at a localized level, increased glucocorticoid action might
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between AT3 activity and HOMA-IR in patients with metabolic syndrome, which was different from this study. The possible explanation is that the AT3 activity may be affected by other factors such as blood lipids and blood pressure in patients with metabolic
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). Of relevance, SHBG was found to linearly increase with ageing while decreasing with increasing BMI values ( 8 , 9 , 11 ). Additionally, SHBG per se has also been shown to be an independent determinant of DM, metabolic syndrome (MetS