Weiwei He
Weiwei He
Department of Endocrinology, Affiliated Hospital of Yanan Medical University, Shaanxi, China
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Bin Wang
Bin Wang
Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China
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Kaida Mu
Kaida Mu
Department of Endocrinology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China
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Jing Zhang
Jing Zhang
Department of Endocrinology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China
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Yanping Yang
Yanping Yang
Department of Endocrinology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China
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Wei Yao
Wei Yao
Department of Endocrinology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China
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Sheli Li
Sheli Li
Department of Endocrinology, Affiliated Hospital of Yanan Medical University, Shaanxi, China
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Jin-an Zhang
Jin-an Zhang
Department of Endocrinology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China
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occurs in generations of the same family has been identified in HT. GD is one of the most common causes of hyperthyroidism characterized by positive thyroid-stimulating hormone (TSH) receptor antibodies (TRAb) and is an organ-specific autoimmune disease
Ru-Xuan Zhao
Ru-Xuan Zhao
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Ting-Ting Shi
Ting-Ting Shi
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Sha Luo
Sha Luo
Department of Nuclear Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Yun-Fu Liu
Yun-Fu Liu
Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Zhong Xin
Zhong Xin
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Jin-Kui Yang
Jin-Kui Yang
Department of Endocrinology, Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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group, 24 patients were considered to be hyperthyroid and another 24 to be euthyroid at the time of assessment, and only patients in the former category were treated with antithyroid drugs. Thyroid function in the control group matched that in the active
Xiaowen Zhang
Xiaowen Zhang
Department of Endocrinology, Drum Tower Hospital affiliated to Nanjing University Medical School, Branch of National Clinical Research Centre for Metabolic Diseases, Endocrine and Metabolic Disease Medical Center, Drum Tower Hospital affiliated to Nanjing University Medical School, Nanjing, China
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Chen Han
Chen Han
Department of Endocrinology, Drum Tower Hospital affiliated to Nanjing University Medical School, Branch of National Clinical Research Centre for Metabolic Diseases, Endocrine and Metabolic Disease Medical Center, Drum Tower Hospital affiliated to Nanjing University Medical School, Nanjing, China
Department of Endocrinology and Metabolism, Drum Tower Clinical Medical College, Southeast University, Nanjing, China
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Department of Endocrinology and Metabolism, Drum Tower Clinical Medical College, Southeast University, Nanjing, China
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Hongwei Wang
Hongwei Wang
State Key Laboratory of Analytical Chemistry for Life Science & Jiangsu Key Laboratory of Molecular Medicine, Nanjing University School of Medicine, Nanjing, China
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Xinghong Sun
Xinghong Sun
Department of Ophthalmology, Nanjing University Medical School Affiliated Drum Tower Hospital, Nanjing, China
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Xin Dou
Xin Dou
Department of Radiology, Nanjing University Medical School Affiliated Drum Tower Hospital, Nanjing, China
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Xueying He
Xueying He
Department of Radiology, Nanjing University Medical School Affiliated Drum Tower Hospital, Nanjing, China
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Di Wu
Di Wu
Department of Radiology, Southeast University Medical School Affiliated Zhongda Hospital, Nanjing, China
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Shanmei Shen
Shanmei Shen
Department of Endocrinology, Drum Tower Hospital affiliated to Nanjing University Medical School, Branch of National Clinical Research Centre for Metabolic Diseases, Endocrine and Metabolic Disease Medical Center, Drum Tower Hospital affiliated to Nanjing University Medical School, Nanjing, China
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Dalong Zhu
Dalong Zhu
Department of Endocrinology, Drum Tower Hospital affiliated to Nanjing University Medical School, Branch of National Clinical Research Centre for Metabolic Diseases, Endocrine and Metabolic Disease Medical Center, Drum Tower Hospital affiliated to Nanjing University Medical School, Nanjing, China
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Xinlin Zhang
Xinlin Zhang
Department of Cardiology, Nanjing University Medical School Affiliated Drum Tower Hospital, Nanjing, China
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Yan Bi
Yan Bi
Department of Endocrinology, Drum Tower Hospital affiliated to Nanjing University Medical School, Branch of National Clinical Research Centre for Metabolic Diseases, Endocrine and Metabolic Disease Medical Center, Drum Tower Hospital affiliated to Nanjing University Medical School, Nanjing, China
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January 2018 to October 2021. GD was diagnosed based on hyperthyroidism associated with anti-thyrotrophic hormone (TSH) receptor autoantibodies (TRAb). TED was diagnosed by the ophthalmology department based on clinical ophthalmic examinations. TED
Zhengrong Jiang
Zhengrong Jiang
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Linghong Huang
Linghong Huang
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Lijun Chen
Lijun Chen
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Jingxiong Zhou
Jingxiong Zhou
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Bo Liang
Bo Liang
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Xuefeng Bai
Xuefeng Bai
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Lizhen Wu
Lizhen Wu
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Huibin Huang
Huibin Huang
Department of Endocrinology, The Second affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China
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Introduction Graves’ disease (GD) is an organ-specific autoimmune disease that commonly manifests as hyperthyroidism and diffuse goitre. The annual incidence of GD is 20–50 cases per 100,000 people worldwide ( 1 , 2 ). The GD phenotype is
Xi Cao
Xi Cao
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Ming Lu
Ming Lu
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Rong-Rong Xie
Rong-Rong Xie
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Li-Ni Song
Li-Ni Song
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Wei-Li Yang
Wei-Li Yang
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Zhong Xin
Zhong Xin
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Guang-Ran Yang
Guang-Ran Yang
Department of Endocrinology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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Jin-Kui Yang
Jin-Kui Yang
Beijing Diabetes Institute, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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were excluded. According to FT4 and TSH concentrations, six subjects with clinical hyperthyroidism and six subjects with clinical hypothyroidism were later excluded. Finally, 1103 euthyroid and 92 SCH subjects were assessed. This study was approved by
Ichelle Maa van Roessel
Ichelle Maa van Roessel
Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, AB Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands
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Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands
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Boudewijn Bakker
Boudewijn Bakker
Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, AB Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands
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Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands
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Hanneke M van Santen
Hanneke M van Santen
Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, AB Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands
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Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands
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Wassim Chemaitilly
Wassim Chemaitilly
Division of Pediatric Endocrinology, UPMC Children’s Hospitalof Pittsburgh, Pittsburgh, Pennsylvania, USA
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or prognostic factor in childhood cancer. In non-CCS adults, hyperthyroidism has been associated with increased cancer risk, especially lung, prostate, breast, ovarian and thyroid cancer ( 36 , 38 ). Correlations have also been reported between serum
G Amiyangoda
G Amiyangoda
Department of Pharmacology, Faculty of Medicine, University of Peradeniya, Sri Lanka
Diabetes and Endocrine Unit, National Hospital, Kandy, Sri Lanka
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Diabetes and Endocrine Unit, National Hospital, Kandy, Sri Lanka
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C N Antonypillai
C N Antonypillai
Diabetes and Endocrine Unit, National Hospital, Kandy, Sri Lanka
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S S C Gunatilake
S S C Gunatilake
Diabetes and Endocrine Unit, National Hospital, Kandy, Sri Lanka
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T T Weerathunge
T T Weerathunge
Department of Community Medicine, Faculty of Medicine, University of Colombo, Sri Lanka
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D Ediriweera
D Ediriweera
Health Data Science Unit, Faculty of Medicine, University of Kelaniya, Sri Lanka
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S G P D Kosgallana
S G P D Kosgallana
Diabetes and Endocrine Unit, National Hospital, Kandy, Sri Lanka
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R D P Jayawardana
R D P Jayawardana
Department of Biochemistry, National Hospital, Kandy, Sri Lanka
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H A N D Thissera
H A N D Thissera
Department of Biochemistry, National Hospital, Kandy, Sri Lanka
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W J Emalka
W J Emalka
Faculty of medicine, University of Peradeniya, Sri Lanka
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H U Daraniyagala
H U Daraniyagala
Faculty of medicine, University of Peradeniya, Sri Lanka
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FT4 values between cases and controls at all time intervals (0, 60, 120, 180, 240, and 300 min) as shown in plot (B) of Fig. 2 and Table 2 . No adverse events or symptoms of hyperthyroidism were reported, and heart rate and blood pressure
Aasem Saif
Aasem Saif
Internal Medicine Department, Cairo University, Cairo, Egypt
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Shrook Mousa
Shrook Mousa
Internal Medicine Department, Cairo University, Cairo, Egypt
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Maha Assem
Maha Assem
Internal Medicine Department, Cairo University, Cairo, Egypt
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Nashwa Tharwat
Nashwa Tharwat
National Nutrition Institute, Cairo, Egypt
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Alaa Abdelhamid
Alaa Abdelhamid
Internal Medicine Department, Cairo University, Cairo, Egypt
Vascular Laboratory, Cairo University, Cairo, Egypt
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Vascular Laboratory, Cairo University, Cairo, Egypt
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. Changes in plasma low-density lipoprotein (LDL)- and high-density lipoprotein cholesterol in hypo- and hyperthyroid patients are related to changes in free thyroxine, not to polymorphisms in LDL receptor or cholesterol ester transfer protein genes
Keina Nishio
Keina Nishio
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
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Akiko Tanabe
Akiko Tanabe
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
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Risa Maruoka
Risa Maruoka
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
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Kiyoko Nakamura
Kiyoko Nakamura
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
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Masaaki Takai
Masaaki Takai
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
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Tatsuharu Sekijima
Tatsuharu Sekijima
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
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Satoshi Tunetoh
Satoshi Tunetoh
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
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Yoshito Terai
Yoshito Terai
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
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Masahide Ohmichi
Masahide Ohmichi
Department of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki-city, Osaka 569-8686, Japan
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to the established protocols from January 2006 to December 2008. Women with a current or past medical condition or medication use that may influence bone mineral metabolism (hyperthyroidism, rheumatoid arthritis, history of fractures that can be
Filippo Ceccato
Filippo Ceccato
Department of Medicine DIMED, University of Padova, Padova, Italy
Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
Department of Neuroscience DNS, University of Padova, Padova, Italy
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Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
Department of Neuroscience DNS, University of Padova, Padova, Italy
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Elisa Selmin
Elisa Selmin
Department of Medicine DIMED, University of Padova, Padova, Italy
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Giorgia Antonelli
Giorgia Antonelli
Department of Medicine DIMED, University of Padova, Padova, Italy
Laboratory Medicine, University-Hospital of Padova, Padova, Italy
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Laboratory Medicine, University-Hospital of Padova, Padova, Italy
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Mattia Barbot
Mattia Barbot
Department of Medicine DIMED, University of Padova, Padova, Italy
Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
Department of Neuroscience DNS, University of Padova, Padova, Italy
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Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
Department of Neuroscience DNS, University of Padova, Padova, Italy
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Andrea Daniele
Andrea Daniele
Department of Medicine DIMED, University of Padova, Padova, Italy
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Marco Boscaro
Marco Boscaro
Department of Medicine DIMED, University of Padova, Padova, Italy
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Mario Plebani
Mario Plebani
Department of Medicine DIMED, University of Padova, Padova, Italy
Laboratory Medicine, University-Hospital of Padova, Padova, Italy
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Laboratory Medicine, University-Hospital of Padova, Padova, Italy
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Carla Scaroni
Carla Scaroni
Department of Medicine DIMED, University of Padova, Padova, Italy
Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
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Endocrine Disease Unit, University-Hospital of Padova, Padova, Italy
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encountered in clinical practice, like subclinical hypercortisolism, hypo- or hyperthyroidism, and so on ( 26 , 27 , 28 ). Two meta-analyses ( 4 , 7 ) previously showed and the Endocrine Society guidelines ( 2 ) have reiterated that corticotropin test
