Arpna Sharma
Arpna Sharma
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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Vijay Simha Baddela
Vijay Simha Baddela
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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Frank Becker
Frank Becker
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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Dirk Dannenberger
Dirk Dannenberger
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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Torsten Viergutz
Torsten Viergutz
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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Jens Vanselow
Jens Vanselow
Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
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, to determine if elevated intrafollicular concentrations of free fatty acids affect GC functionality and thus may contribute to declined fertility rates as experienced by cows during NEB, in the present study, we analyzed the in vitro effects of
Sebastião Freitas de Medeiros
Sebastião Freitas de Medeiros
Department of Gynecology and Obstetrics, Medical School, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Cinthia Marenza Ormond
Cinthia Marenza Ormond
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Matheus Antônio Souto de Medeiros
Matheus Antônio Souto de Medeiros
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Nayara de Souza Santos
Nayara de Souza Santos
Department of Gynecology and Obstetrics, Medical School, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Camila Regis Banhara
Camila Regis Banhara
Department of Gynecology and Obstetrics, Medical School, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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Márcia Marly Winck Yamamoto
Márcia Marly Winck Yamamoto
Tropical Institute of Reproductive Medicine and Menopause, Cuiabá, Mato Grosso, Brazil
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.2003-0030 ) 15583024 10.1210/er.2003-0030 8 Rosenfield RL Barnes RB Cara JF Lucky AW. Dysregulation of cytochrome P450c 17 alpha as a cause of polycystic ovarian syndrome . Fertility and Sterility 1990 53 785 – 791 . ( doi:10
Renea A Taylor
Renea A Taylor
Department of Physiology, Cancer Program and Obesity and Metabolic Disease Program, Biomedicine Discovery Institute, Monash University, Wellington Road, Victoria 3800, Australia
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Jennifer Lo
Jennifer Lo
Department of Physiology, Cancer Program and Obesity and Metabolic Disease Program, Biomedicine Discovery Institute, Monash University, Wellington Road, Victoria 3800, Australia
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Natasha Ascui
Natasha Ascui
Department of Physiology, Cancer Program and Obesity and Metabolic Disease Program, Biomedicine Discovery Institute, Monash University, Wellington Road, Victoria 3800, Australia
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Matthew J Watt
Matthew J Watt
Department of Physiology, Cancer Program and Obesity and Metabolic Disease Program, Biomedicine Discovery Institute, Monash University, Wellington Road, Victoria 3800, Australia
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:10.1038/nrc2174 ). 63 Chavarro JE Toth TL Wright DL Meeker JD Hauser R . Body mass index in relation to semen quality, sperm DNA integrity, and serum reproductive hormone levels among men attending an infertility clinic . Fertility and
Elizabeth Micks
Elizabeth Micks
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Greta B Raglan
Greta B Raglan
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Jay Schulkin
Jay Schulkin
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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Department of Obstetrics and Gynecology, Department of Research, University of Washington, Box 356460, 1959 NE Pacific Street, Seattle, Washington, USA
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illustrates the timeline for development of progestin contraceptives. In the 1920s, scientists observed that steroid extracts administered to animals inhibited fertility. In 1942, Russell Marker identified a technique to convert diosgenin, a steroid precursor
Luigi Laino
Luigi Laino
Department of Molecular Medicine, Department of Pediatrics and Hematology, Psychology Department, Department of Pediatric Surgery, Medical Genetics, San Camillo-Forlanini Hospital, Sapienza University, A.O. San Camillo-Forlanini, Padiglione Morgagni, I piano, UOC Laboratorio di Genetica Medica, Circonvallazione Gianicolense 87, Rome 00152, Italy
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Silvia Majore
Silvia Majore
Department of Molecular Medicine, Department of Pediatrics and Hematology, Psychology Department, Department of Pediatric Surgery, Medical Genetics, San Camillo-Forlanini Hospital, Sapienza University, A.O. San Camillo-Forlanini, Padiglione Morgagni, I piano, UOC Laboratorio di Genetica Medica, Circonvallazione Gianicolense 87, Rome 00152, Italy
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Nicoletta Preziosi
Nicoletta Preziosi
Department of Molecular Medicine, Department of Pediatrics and Hematology, Psychology Department, Department of Pediatric Surgery, Medical Genetics, San Camillo-Forlanini Hospital, Sapienza University, A.O. San Camillo-Forlanini, Padiglione Morgagni, I piano, UOC Laboratorio di Genetica Medica, Circonvallazione Gianicolense 87, Rome 00152, Italy
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Barbara Grammatico
Barbara Grammatico
Department of Molecular Medicine, Department of Pediatrics and Hematology, Psychology Department, Department of Pediatric Surgery, Medical Genetics, San Camillo-Forlanini Hospital, Sapienza University, A.O. San Camillo-Forlanini, Padiglione Morgagni, I piano, UOC Laboratorio di Genetica Medica, Circonvallazione Gianicolense 87, Rome 00152, Italy
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Carmelilia De Bernardo
Carmelilia De Bernardo
Department of Molecular Medicine, Department of Pediatrics and Hematology, Psychology Department, Department of Pediatric Surgery, Medical Genetics, San Camillo-Forlanini Hospital, Sapienza University, A.O. San Camillo-Forlanini, Padiglione Morgagni, I piano, UOC Laboratorio di Genetica Medica, Circonvallazione Gianicolense 87, Rome 00152, Italy
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Salvatore Scommegna
Salvatore Scommegna
Department of Molecular Medicine, Department of Pediatrics and Hematology, Psychology Department, Department of Pediatric Surgery, Medical Genetics, San Camillo-Forlanini Hospital, Sapienza University, A.O. San Camillo-Forlanini, Padiglione Morgagni, I piano, UOC Laboratorio di Genetica Medica, Circonvallazione Gianicolense 87, Rome 00152, Italy
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Anna Maria Rapone
Anna Maria Rapone
Department of Molecular Medicine, Department of Pediatrics and Hematology, Psychology Department, Department of Pediatric Surgery, Medical Genetics, San Camillo-Forlanini Hospital, Sapienza University, A.O. San Camillo-Forlanini, Padiglione Morgagni, I piano, UOC Laboratorio di Genetica Medica, Circonvallazione Gianicolense 87, Rome 00152, Italy
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Giacinto Marrocco
Giacinto Marrocco
Department of Molecular Medicine, Department of Pediatrics and Hematology, Psychology Department, Department of Pediatric Surgery, Medical Genetics, San Camillo-Forlanini Hospital, Sapienza University, A.O. San Camillo-Forlanini, Padiglione Morgagni, I piano, UOC Laboratorio di Genetica Medica, Circonvallazione Gianicolense 87, Rome 00152, Italy
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Irene Bottillo
Irene Bottillo
Department of Molecular Medicine, Department of Pediatrics and Hematology, Psychology Department, Department of Pediatric Surgery, Medical Genetics, San Camillo-Forlanini Hospital, Sapienza University, A.O. San Camillo-Forlanini, Padiglione Morgagni, I piano, UOC Laboratorio di Genetica Medica, Circonvallazione Gianicolense 87, Rome 00152, Italy
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Paola Grammatico
Paola Grammatico
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) . Fertility and Sterility 2011 95 2683 – 2686 . ( doi:10.1016/j.fertnstert.2011.01.152 ). 27 Ravel C Lorenco D Dessolle L Mandelbaum J McElreavey K Darai E Siffroi JP . Mutational analysis of the WNT gene family in women with Mayer
Line K Johnson
Line K Johnson
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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Kirsten B Holven
Kirsten B Holven
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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Njord Nordstrand
Njord Nordstrand
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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Jan R Mellembakken
Jan R Mellembakken
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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Tom Tanbo
Tom Tanbo
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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Jøran Hjelmesæth
Jøran Hjelmesæth
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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Morbid Obesity Centre, Department of Nutrition, Norwegian National Advisory Unit on Familial Hypercholesterolemia, Department of Gynecology, Institute of Clinical Medicine, Department of Endocrinology, Vestfold Hospital Trust, PO Box 2168, 3103 Tønsberg, Norway
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with PCOS reduces hyperandrogenism, normalizes menstrual function and improves fertility (6) . Furthermore, weight reduction improves several components of MS such as high blood pressure (BP), dyslipidemia and dysglycemia (7, 8) . Few studies have
Mojca Jensterle
Mojca Jensterle
Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre, Ljubljana, Slovenia
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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Nika Aleksandra Kravos
Nika Aleksandra Kravos
Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre, Ljubljana, Slovenia
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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Simona Ferjan
Simona Ferjan
Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre, Ljubljana, Slovenia
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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Katja Goricar
Katja Goricar
University of Ljubljana, Faculty of Medicine, Institute of Biochemistry, Pharmacogenetics Laboratory, Ljubljana, Slovenia
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Vita Dolzan
Vita Dolzan
University of Ljubljana, Faculty of Medicine, Institute of Biochemistry, Pharmacogenetics Laboratory, Ljubljana, Slovenia
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Andrej Janez
Andrej Janez
Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre, Ljubljana, Slovenia
University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
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– 1901 . ( https://doi.org/10.1007/s40265-018-1025-0 ) 13 Azziz R . Introduction: determinants of polycystic ovary syndrome . Fertility and Sterility 2016 4 – 5 . ( https://doi.org/10.1016/j.fertnstert.2016.05.009 ) 14 Jayasena CN Franks
M Axelstad
M Axelstad
Technical University of Denmark, National Food Institute, Kongens Lyngby, Denmark
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U Hass
U Hass
Technical University of Denmark, National Food Institute, Kongens Lyngby, Denmark
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M Scholze
M Scholze
Brunel University, Uxbridge, UK
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S Christiansen
S Christiansen
Technical University of Denmark, National Food Institute, Kongens Lyngby, Denmark
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A Kortenkamp
A Kortenkamp
Brunel University, Uxbridge, UK
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J Boberg
J Boberg
Technical University of Denmark, National Food Institute, Kongens Lyngby, Denmark
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/kg bw/day of paracetamol ( 17 ). Several studies have examined the effects of paracetamol in adult rodents, some indicating toxicity to male reproductive organs. Oral exposure to 1000 mg/kg bw/day for 30 days impaired male fertility and sperm count
Srdjan Pandurevic
Srdjan Pandurevic
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Ilaria Mancini
Ilaria Mancini
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
Unit of Gynecology and Obstetrics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy
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Unit of Gynecology and Obstetrics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy
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Dimitri Mitselman
Dimitri Mitselman
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Matteo Magagnoli
Matteo Magagnoli
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Rita Teglia
Rita Teglia
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Roberta Fazzeri
Roberta Fazzeri
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Paola Dionese
Paola Dionese
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Carolina Cecchetti
Carolina Cecchetti
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Massimiliamo Caprio
Massimiliamo Caprio
Department of Human Sciences and Quality of Life Promotion, San Raffaele Roma Open University, Rome, Italy
Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele, Rome, Italy
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Laboratory of Cardiovascular Endocrinology, IRCCS San Raffaele, Rome, Italy
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Costanzo Moretti
Costanzo Moretti
Department of Systems Medicine, Unit of Endocrinology, University of Rome Tor Vergata, Rome, Italy
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Justyna Sicinska
Justyna Sicinska
Dermatology Clinic of CSK MSWiA Hospital, Warsaw, Poland
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Alessandro Agostini
Alessandro Agostini
Department of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, Bologna, Italy
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Domenica Gazineo
Domenica Gazineo
Teaching Hospital, S. Orsola Hospital, Bologna, Italy
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Lea Godino
Lea Godino
Teaching Hospital, S. Orsola Hospital, Bologna, Italy
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Ignacio Sajoux
Ignacio Sajoux
Epigenomics in Endocrinology and Nutrition Group, Instituto de Investigacion Sanitaria (IDIS), Complejo Hospitalario Universitario de Santiago (CHUS/SERGAS), Spain
Medical Department Pronokal Group, Barcelona, Spain
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Medical Department Pronokal Group, Barcelona, Spain
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Flaminia Fanelli
Flaminia Fanelli
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Cristina M Meriggiola
Cristina M Meriggiola
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
Unit of Gynecology and Obstetrics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy
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Unit of Gynecology and Obstetrics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy
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Uberto Pagotto
Uberto Pagotto
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Alessandra Gambineri
Alessandra Gambineri
Division of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum University of Bologna, Bologna, Italy
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treatment revealed a large increase in ovulatory cycles detected in the experimental group. To our knowledge, this is the first RCT to test the efficacy of a ketogenic diet for potential fertility treatment in a robust way, using both US and biochemical
Rohit Barnabas
Rohit Barnabas
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
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Swati Jadhav
Swati Jadhav
Department of Endocrinology, Vydehi Institute of Medical Sciences and Research Centre, Bengaluru, India
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Anurag Ranjan Lila
Anurag Ranjan Lila
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
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Sirisha Kusuma Boddu
Sirisha Kusuma Boddu
Consultant Pediatric Endocrinology & Diabetes, Rainbow Children’s Hospital, Hyderabad, India
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Saba Samad Memon
Saba Samad Memon
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
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Sneha Arya
Sneha Arya
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
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Samiksha Chandrashekhar Hegishte
Samiksha Chandrashekhar Hegishte
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
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Manjiri Karlekar
Manjiri Karlekar
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
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Virendra A Patil
Virendra A Patil
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
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Vijaya Sarathi
Vijaya Sarathi
Department of Endocrinology, Vydehi Institute of Medical Sciences and Research Centre, Bengaluru, India
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Nalini S Shah
Nalini S Shah
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
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Tushar Bandgar
Tushar Bandgar
Department of Endocrinology, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
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(from 8 and 4 cc to 15 cc and 12 cc, respectively) in two patients and sperm count (from azoospermia to 3 million/mL resulting in fertility) in one. hCG-treatment was attempted in two patients. In the first patient, the use of 5000 units twice/week of
