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/ornithine ratio (AOR) decreased in breast cancer patients and this could be a marker ( 30 ). The ornithine levels in all of the study groups were increased and statistically significant ( Table 3 ). Increased ornithine levels may also underpin the development of
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reasonable to infer that the higher prevalence of DN in the present study was largely due to poor diabetes care in the past. We found that birth location was associated with the development of DN in the present study. This is an important sociodemographic
Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands
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Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands
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Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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Endocrinology Clinic, Cluj County Emergency Hospital, Cluj-Napoca, Romania
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Department of Nuclear Medicine and Endocrine Tumors, Institute of Oncology ‘Prof. Dr. Ion Chiricuta’, Cluj-Napoca, Romania
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dephosphorylation remains to be determined. Although the heterozygous GC genotype, and most likely also the homozygous CC genotype, are demonstrated to predispose to development of NMTC by inducing hyperactivation of the PI3K-Akt-mTOR pathway upon the encounter of
CEB – Centro de Engenharia Biológica, Universidade do Minho, Braga, Portugal
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CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde & Instituto Universitário de Ciências da Saúde, Gandra, Portugal
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microbiome ( 12 ) have also been suggested to play a role on type 1 diabetes development. The heterogeneity and variation in the pathogenic process and phenotypic characteristics makes it difficult to diagnose and to treat the disease at an early stage ( 13
Department of Endocrinology and Diabetology, The Children’s Memorial Health Institute, Warsaw, Poland
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a + p hypothalamic areas ( Fig. 2 ). These 109 CP patients diagnosed with preoperative involvement of a + p hypothalamic areas were included in our analysis of survival and weight development during follow-up. In 55 of these 109 CP patients (50
Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, People’s Republic of China
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Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou, People’s Republic of China
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Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou, People’s Republic of China
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of differentially expressed genes (DEGs) in the development of steatosis. (A) Volcano plot of GSE48452. (B) Volcano plot of GSE89632. (C) Venn diagram displaying 31 up-regulated genes between healthy controls (HCs) and simple steatosis (SS) subjects
West Cancer Center, Memphis, Tennessee, USA
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West Cancer Center, Memphis, Tennessee, USA
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, androgen that is responsible for the development and maintenance of the prostate gland, is also responsible for the development of PCa. There are multiple stages of PCa progression; each stage is determined based on the severity of the disease, castration
Department of Epidemiology St. Luke’s International University Graduate School of Public Health, Tokyo, Japan
Fujita Health University Toyoake, Japan
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Department of Epidemiology St. Luke’s International University Graduate School of Public Health, Tokyo, Japan
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still controversial. Previous meta-analyses and systematic reviews, which included four randomized control trials ( 14 , 15 , 16 , 17 ), reported no difference in malignancy development between intensively treated and standardly treated diabetic
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foetus for development ( 5 ). The need for maternal insulin is an elevated result of gestational insulin resistance, which is impacted by attenuated food intake and placental hormone production. Consequently, the sizes of pancreatic β cells are enhanced
Leiden Institute for Brain and Cognition, Leiden, The Netherlands
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Leiden Institute for Brain and Cognition, Leiden, The Netherlands
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Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado
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Leiden Institute for Brain and Cognition, Leiden, The Netherlands
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currently non-existing. There is a need for this knowledge given that it could be useful in designing tailored interventions targeting emotion regulation strategies to reduce the impact of the additional sex chromosome on social-emotional development and