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limited. Menin and NFκB NFκB is a transcription factor that functions as an important regulator of apoptosis and proto-oncogene. In intact cells, NFκB is predominantly localized in the cytoplasm in an inactive form, bound to the inhibitor protein IkB
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fat / fat Reduced meal-induced gastrin secretion Gastrin Lacourse et al . 1997 Neurodegenerative disease Cpe KO Absent neuroprotection BDNF, SST Lou et al . 2005 , Billova et al . 2007 The apoptosis and dysfunction
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vascular endothelial growth factor and increased angiogenesis and apoptosis Maia et al. (44) 2016 Rats Orogastric administration (T4) Postnatal days 0, 21, 42 Reversible reduced growth and reversible increased percentage of trabecular bone
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an important role in the development of tumors. PGE 2 can stimulate cell proliferation, angiogenesis and motility while inhibiting apoptosis and immune surveillance ( 8 , 9 , 10 ). Reduced 15-PGDH and SLCO2A1 are believed to contribute to elevated
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-8924(00)01816-X ) 10.1016/S0962-8924(00)01816-X 10932095 19 Sadanandam A Rosenbaugh EG Singh S Varney M Singh RK. Semaphorin 5A promotes angiogenesis by increasing endothelial cell proliferation, migration, and decreasing apoptosis
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to the S phase of the cell cycle and upregulation of the expression of p27 results in cell cycle arrest and apoptosis (33) . The percentage area stained for p27 was significantly higher for ACC samples than for all the other groups of samples
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Raphael Recanati Genetic Institute, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel
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mutation. The evolution of the disorder from hypoglycemia to overt diabetes is very complex, and the pathogenic mechanism may involve both β-cell exhaustion and apoptosis. There is some genetic evidence for a role of IGF-1 in glucose metabolism. In
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hormone levels, including increased circulating oestrogen ( 8 , 11 , 12 ). The increase in oestrogen is thought to alter the risk of malignancy via its effects on cellular proliferation, differentiation and apoptosis ( 7 ). Insulin-like growth factor I
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. ( https://doi.org/10.1016/j.tem.2013.12.006 ) 12 O'Brien CA Jia D Plotkin LI Bellido T Powers CC Stewart SA Manolagas SC Weinstein RS . Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone
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association with inflammation and apoptosis (29) . Apoptosis occurs frequently as a tissue regulatory process in the developing embryo, for example as cells with chromosomal or gene abnormalities are eliminated. It is also necessary for implantation. Ang II