Department of Endocrinology, University of Manchester, School of Medical Sciences, Manchester, UK
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Department of Endocrinology, University of Manchester, School of Medical Sciences, Manchester, UK
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conventional fracture risk factors, as well as underlying cancer diagnosis, staging and treatment history were captured from the patients’ electronic medical records. Images and reports of all the scans, including DXA, as well as magnetic resonance imaging (MRI
National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
Department of Pathology, Huashan Hospital, Shanghai Medical School, Shanghai, China
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
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National Center for Neurological Disorders, Shanghai, China
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China
Neurosurgical Institute of Fudan University, Shanghai, China
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China
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a dura tail sign on MRI. Sellar germinoma and sellar glioma are two tumor entities that predominate in young patients. In our database, sellar germinoma was only identified in patients younger than 30 years. Sellar glioma presented with a
Nanchang University, Nanchang, Jiangxi Province, China
Institute of Neuroscience, Nanchang University, Nanchang, Jiangxi Province, China
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Nanchang University, Nanchang, Jiangxi Province, China
Institute of Neuroscience, Nanchang University, Nanchang, Jiangxi Province, China
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Nanchang University, Nanchang, Jiangxi Province, China
Institute of Neuroscience, Nanchang University, Nanchang, Jiangxi Province, China
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Nanchang University, Nanchang, Jiangxi Province, China
Institute of Neuroscience, Nanchang University, Nanchang, Jiangxi Province, China
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Nanchang University, Nanchang, Jiangxi Province, China
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Department of Urology, the 2nd affiliated hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi Province, China
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Nanchang University, Nanchang, Jiangxi Province, China
Institute of Neuroscience, Nanchang University, Nanchang, Jiangxi Province, China
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reported in cancer, but it has not been fully elucidated in invasive PitNETs. The preoperative MRI performance of non-invasive and invasive PitNETs was depicted in Fig. 2A . To further evaluate SLC7A11 as a biomarker in invasive PitNETs, we performed
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Department of Endocrinology and Diabetes, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK
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Department of Endocrinology and Diabetes, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK
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patient deaths. Magnetic Resonance Imaging (MRI) reports were also accessed and linked for identifying pituitary tumours. The International Classification of Diseases (ICD) 9–10th revision codes were used in the SMR to identify hospital inpatient and
Wolfson Diabetes and Endocrine Centre, Addenbrooke’s Hospital, Cambridge, UK
IMED Biotech Unit, Clinical Discovery Unit, AstraZeneca, UK
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Wolfson Diabetes and Endocrine Centre, Addenbrooke’s Hospital, Cambridge, UK
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Department of Nuclear Medicine, Addenbrooke’s Hospital, Cambridge, UK
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Wolfson Diabetes and Endocrine Centre, Addenbrooke’s Hospital, Cambridge, UK
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Department of Nuclear Medicine, Addenbrooke’s Hospital, Cambridge, UK
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initial imaging modality used in 22 cases. Of these, CT successfully detected the tumour in 15 cases and failed to localise 7 tumours (sensitivity, 68%). Magnetic resonance imaging (MRI) correctly detected 5 out of 9 insulinoma (sensitivity, 56%). Of the
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calculated using British references (14) . Magnetic resonance imaging (MRI) scans were performed in a 1.5 Tesla unit (Sigma; GE, Milwaukee, WI, USA) using T1- and T2-weighted sagittal and coronal scans. The control group consisted of 400 healthy Brazilian
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Endoscopic Skull Base Unit, Department of Neurosurgery, Hospital Universitario HM Puerta del Sur, Madrid, Spain
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performed with MRI with 1.5T, GE 450w. Sagittal and coronal T1, T2-weighted and dynamic sequences, with gadolinium contrast was performed preoperatively and before any medical or surgical treatment, and 3–6 months postoperatively. Depending on tumor size, PA
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(MIBI) scan ( Fig. 1B ) revealed bilateral parathyroid adenoma. Figure 1 Left adrenal tumor on CT scan (A), bilateral parathyroid adenoma on MIBI (B), pituitary microadenoma on MRI (C) of the proband (III:4). Right adrenal tumor on CT scan of
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.005. Full pre-operative work-up data were not available from all sites. However, full data were available from two centres, representing 35 of the 66 patients with tumours <2 cm. As part of work-up, 31 (89%) patients received CT imaging, 11 (31%) MRI, 20 (57
Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Endocrinology, Abdominal Centre, University of Helsinki and HUS, Helsinki, Finland
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Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland
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University Hospital with in-house methods. A whole-body CT and a brain MRI or a brain CT were performed prior to treatment initiation as well. Before each treatment cycle, we measured WBC, CRP, sodium, potassium, calcium, creatinine, ALT, ALP, bilirubin