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The Working Group for Renaming Diabetes Insipidus
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Hiroshi Arima Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
Japan Endocrine Society

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Timothy Cheetham Department of Paediatric Endocrinology, Newcastle University Faculty of Medical Sciences, Great North Children’s Hospital, Royal Victoria Infirmary, Newcastle upon Tyne, UK
European Society for Pediatric Endocrinology

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Mirjam Christ-Crain Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, University of Basel, Switzerland
European Society of Endocrinology

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Deborah Cooper Department of Endocrinology, Diabetes and Metabolism, University Hospital Basel, University of Basel, Switzerland

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Mark Gurnell European Society of Endocrinology
Wellcome-MRC Institute of Metabolic Science, University of Cambridge & Addenbrooke’s Hospital, Cambridge Biomedical Campus, Cambridge, UK

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Juliana B Drummond Faculdade de Medicina da UFMG, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
Brazilian Society of Endocrinology and Metabolism

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Miles Levy Endocrinology, University Hospitals of Leicester, Leicester, UK
Society for Endocrinology

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Ann I McCormack Hormones and Cancer Group, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
Endocrine Society of Australia

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Joseph Verbalis Endocrinology and Metabolism, Georgetown University Medical Center, Washington DC, District of Columbia, USA
Endocrine Society

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John Newell-Price Endocrine Society
Department of Oncology and Metabolism, The Medical School, University of Sheffield, Sheffield, UK

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John A H Wass Department of Endocrinology, Oxford Centre for Diabetes Endocrinology & Metabolism – Endocrinology, Oxford, UK
Pituitary Society

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What’s in a name? That which we call a rose/By any other name would smell as sweet’ (Juliet, from Romeo and Juliet by William Shakespeare). Shakespeare’s implication is that a name is nothing but a word, and it therefore represents a convention with no intrinsic meaning. While this may be relevant to romantic literature, disease names do have real meanings, and consequences, in medicine. Hence, there must be a very good rationale for changing the name of a disease that has a centuries-old historical context. A working group of representatives from national and international endocrinology, and pediatric endocrine societies now proposes changing the name of ‘diabetes insipidus’ to ‘arginine vasopressin deficiency (AVP-D)’ for central etiologies, and ‘arginine vasopressin resistance (AVP-R)’ for nephrogenic etiologies. This article provides both the historical context and the rationale for this proposed name change.

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