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Qiuli Liu, Lin-ang Wang, Jian Su, Dali Tong, Weihua Lan, Luofu Wang, Gaolei Liu, Jun Zhang, Victor Wei Zhang, Dianzheng Zhang, Rongrong Chen, Qingyi Zhu, and Jun Jiang

Introduction Congenital adrenal hyperplasia (CAH) is one of the most severe disorders of metabolism with an overall incidence of approximately 1:15,000 worldwide ( 1 ). CAH encompasses a group of enzymatic deficiencies of cortisol synthesis

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Flavia Letícia Martins Peçanha, Reinaldo Sousa dos Santos, and Wagner Seixas da-Silva

Introduction Thyroid hormones exert important effects on basal and adaptive metabolism ( 1 ). Although several studies have shown that triiodothyronine (T 3 ) may regulate glucose uptake and oxygen consumption ( 2 , 3 , 4 , 5 , 6 , 7 , 8

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Aneta Gawlik, Michael Shmoish, Michaela F Hartmann, Stefan A Wudy, Zbigniew Olczak, Katarzyna Gruszczynska, and Ze’ev Hochberg

there is possibility of multiple diagnoses or before starting therapy with potentially hepatotoxic medications’ ( 8 ). The consequences of obesity-related NAFLD on liver metabolism are insufficiently understood ( 8 ). As steroid hormones are partially

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Agnieszka Adamska, Aleksandra Maria Polak, Anna Krentowska, Agnieszka Łebkowska, Justyna Hryniewicka, Monika Leśniewska, and Irina Kowalska

regulation of lipid and carbohydrate metabolism ( 11 ). In an experimental study, Meex et al . showed that fetuin-B impaired insulin action in myotubes and hepatocytes and caused glucose intolerance in mice, whereas knockdown of this protein in obese mice

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Elisabet Einarsdottir, Minna Pekkinen, Kaarel Krjutškov, Shintaro Katayama, Juha Kere, Outi Mäkitie, and Heli Viljakainen

inflammatory processes in adipose tissue ( 5 ). It is crucial to understand the metabolism and targeted effects of vitamin D and especially how these are affected in obesity. To date, we know that vitamin D supplementation increases circulating 25-OHD in

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Masatada Watanabe, Shuji Ohno, and Hiroshi Wachi

adrenomedullary system to stress in patients with atopic dermatitis . Journal of Clinical Endocrinology and Metabolism 2002 87 4245 – 4251 . ( doi:10.1210/jc.2001-010872 ) 19 Watanabe M Nakajin S. Forskolin up-regulates aromatase (CYP19) activity

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Dmitry M Davydov and Malik K Nurbekov

status in individuals with and without type 2 diabetes (e.g., altered erythrocyte physiology), individual variance in both glycemic parameters can reflect different aspects of energy metabolism that are modulated by different gene polymorphisms. However

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Julia Kubiak, Per Medbøe Thorsby, Elena Kamycheva, and Rolf Jorde

HOMA-IR values above the median for the cohort, combined with low baseline serum 25(OH)D; but again, no significant effects of vitamin D were found. Previous studies on vitamin D and lipid and glucose metabolism have generally included standard

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Piera Rizzolo, Valentina Silvestri, Virginia Valentini, Veronica Zelli, Agostino Bucalo, Ines Zanna, Simonetta Bianchi, Maria Grazia Tibiletti, Antonio Russo, Liliana Varesco, Gianluca Tedaldi, Bernardo Bonanni, Jacopo Azzollini, Siranoush Manoukian, Anna Coppa, Giuseppe Giannini, Laura Cortesi, Alessandra Viel, Marco Montagna, Paolo Peterlongo, Paolo Radice, Domenico Palli, and Laura Ottini

in genes involved in estrogen biosynthesis and metabolism pathways, such as Cytochrome P450 family 17 subfamily A member 1 ( CYP17A1 ) and Cytochrome P450 family 1 subfamily B member 1 ( CYP1B1 ), may cause an increased risk of hormone-related cancers

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Masafumi Tetsuka and Misato Tanakadate

the local glucocorticoid environment in the bovine COC is eloquently regulated during oocyte maturation. The physiological significance of the HSD11B-led glucocorticoid metabolism in the oocyte maturation has not yet been clarified. However, it is