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R Walia, M Singla, K Vaiphei, S Kumar, and A Bhansali

virilization of external genitalia, prospects of restoring normal appearance of external genitalia and fertility and parent’s/patient’s preferences. Genital surgery is often required; however, the type and time of surgery are still debatable ( 5 ). Most of the

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Bernardo Maia, Leandro Kasuki, and Mônica R Gadelha

therapy and radiotherapy ( 4 , 6 , 7 ). Current treatments Surgical treatment Surgery is the gold standard treatment of acromegaly since it represents the only therapy capable of rapidly curing acromegaly ( 4 ). With experienced pituitary

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G Giuffrida, F Ferraù, R Laudicella, O R Cotta, E Messina, F Granata, F F Angileri, A Vento, A Alibrandi, S Baldari, and S Cannavò

In this patient, macroprolactinoma was diagnosed when she was 42 years old and trans-sphenoidal surgery was performed after few months of ineffective high-dose cabergoline treatment. At the age of 55 years, serum PRL concentrations remarkably

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Cecilia Follin and Sven Karlsson

diabetes and hypertension ( 3 , 4 ). The aims of treatment for acromegaly are to control/reduce tumour size, normalise GH and insulin-like growth factor 1 (IGF-1) levels and to improve comorbidities. Current treatments consist of surgery, medical therapy

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Yen Kheng Tan, Yu Heng Kwan, David Choon Liang Teo, Marieke Velema, Jaap Deinum, Pei Ting Tan, Meifen Zhang, Joan Joo Ching Khoo, Wann Jia Loh, Linsey Gani, Thomas F J King, Eberta Jun Hui Tan, Shui Boon Soh, Vanessa Shu Chuan Au, Tunn Lin Tay, Lily Mae Quevedo Dacay, Keng Sin Ng, Kang Min Wong, Andrew Siang Yih Wong, Foo Cheong Ng, Tar Choon Aw, Yvonne Hui Bin Chan, Khim Leng Tong, Sheldon Shao Guang Lee, Siang Chew Chai, and Troy Hai Kiat Puar

surgical treatment ( 2 , 5 ). Adrenal vein sampling (AVS) is required to differentiate unilateral from bilateral PA and is technically challenging to perform ( 7 ). If surgery leads to better outcomes than medical treatment, then it will be ideal for all

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Louise Vølund Larsen, Delphine Mirebeau-Prunier, Tsuneo Imai, Cristina Alvarez-Escola, Kornelia Hasse-Lazar, Simona Censi, Luciana A Castroneves, Akihiro Sakurai, Minoru Kihara, Kiyomi Horiuchi, Véronique Dorine Barbu, Francoise Borson-Chazot, Anne-Paule Gimenez-Roqueplo, Pascal Pigny, Stephane Pinson, Nelson Wohllk, Charis Eng, Berna Imge Aydogan, Dhananjaya Saranath, Sarka Dvorakova, Frederic Castinetti, Attila Patocs, Damijan Bergant, Thera P Links, Mariola Peczkowska, Ana O Hoff, Caterina Mian, Trisha Dwight, Barbara Jarzab, Hartmut P H Neumann, Mercedes Robledo, Shinya Uchino, Anne Barlier, Christian Godballe, and Jes Sloth Mathiesen

diagnosed in 10/10 cases. 9/10 were diagnosed in relation to parathyroid surgery as a synchronous MTC and 1/10 was diagnosed 15 years after parathyroid surgery, as a metachronous MTC. In three cases, MTC was not suspected during preoperative PHPT work

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Laura J Reid, Bala Muthukrishnan, Dilip Patel, Mike S Crane, Murat Akyol, Andrew Thomson, Jonathan R Seckl, and Fraser W Gibb

). We have collated one of the largest cohorts of patients presenting for specialist endocrine assessment of PHPT, characterised in detail with respect to demographics, clinical features, biochemistry, imaging, surgery, pathology and subsequent outcomes

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Hanbaro Kim, Ki Byung Song, Dae Wook Hwang, Jae Hoon Lee, Shadi Alshammary, and Song Cheol Kim

curative intent ( 6 , 7 ). Currently, complete surgical removal is considered the first-line treatment for patients with PNET, although the recommendation for surgery is size dependent for NF-PNETs. The primary goal of surgical resection is curative

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Manjeetkaur Sehemby, Prachi Bansal, Vijaya Sarathi, Ashwini Kolhe, Kanchan Kothari, Swati Jadhav-Ramteke, Anurag R Lila, Tushar Bandgar, and Nalini S Shah

MRI Extent of surgery Gross description size of tumor Histopathology Post op testosterone (ng/mL) 1 LO Cystic – Cystic LSO Solid cystic3.6 × 4 × 2 cm Sertoli Leydig cell tumorIntermediateDifferentiated 0.4 2 RO

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Klaudia Zajkowska, Janusz Kopczyński, Stanisław Góźdź, and Aldona Kowalska

the diagnostic criteria of NIFTP The diagnosis of NIFTP can only be made after histological examination of the entire tumour removed during surgery and is based on strictly defined inclusion and exclusion criteria ( 4 , 35 ). According to the