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Klaudia Zajkowska, Janusz Kopczyński, Stanisław Góźdź, and Aldona Kowalska

introduction of the new nomenclature, it appears that the initial calculations were overestimated ( 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ). According to the meta-analysis conducted by Bychkov et al . (25 studies, 46

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Alessandra Gambineri and Carla Pelusi

). Observational cross-sectional studies performed on PCOS and included by Moran et al. in a meta-analysis estimate that the odds of T2DM are four times as high for women with PCOS compared with controls ( 12 ). A subgroup matched for BMI confirmed that the odds

Open access

Yael Sofer, Nava Nevo, Michal Vechoropoulos, Gabi Shefer, Etty Osher, Nathan Landis, Karen Tordjman, Geoffrey L Hammond, and Naftali Stern

waist circumference ( 12 ). A meta-analysis of more than ten prospective studies has demonstrated that women with SHBG levels higher than 60 nmol/L had 80% lower risk of type 2 diabetes ( 7 ). Men with SHBG higher than 28.3 nmol/L had a 52% smaller risk

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Kristin Ottarsdottir, Margareta Hellgren, David Bock, Anna G Nilsson, and Bledar Daka

different cohorts including men and women, respectively, suggesting a causal effect. The mechanism behind the association between SHGB and type 2 diabetes is not fully understood, but may be mediated through insulin resistance ( 5 ). In a meta-analysis

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Katherine A Bolton, Kelly A Avery-Kiejda, Elizabeth G Holliday, John Attia, Nikola A Bowden, and Rodney J Scott

cancer cases and 7771 controls ( 18 ). A meta-analysis conducted recently on the effect of this repeat on the risk of developing breast cancer (which included 11 studies of various ethnicity groups with a total of 7047 cases and 12,096 controls) reported

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Kristine Zøylner Swan, Steen Joop Bonnema, Marie Louise Jespersen, and Viveque Egsgaard Nielsen

the clinical applicability of thyroid SWE even more. In a smaller study, but in line with our results, Bardet et al . ( 32 ) found no difference in EI between 110 benign and 21 malignant nodules with indeterminate cytology. Moreover, a recent meta-analysis

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Huguette S Brink, Aart Jan van der Lely, and Joke van der Linden

( 46 ). A systematic review and meta-analysis of adiponectin concentrations in 560 GD patients and 781 controls underlined a significantly decreased adiponectin level in GD patients vs controls ( 45 ). However, it must be noted that results are in light

Open access

K Amrein, A Papinutti, E Mathew, G Vila, and D Parekh

. Vitamin D deficiency as a risk factor for infection, sepsis and mortality in the critically ill: systematic review and meta-analysis. Critical Care 2014 18 660 . ( https://doi.org/10.1186/s13054-014-0660-4 ) 19 Parekh D Patel JM Scott A Lax S

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Aasem Saif, Shrook Mousa, Maha Assem, Nashwa Tharwat, and Alaa Abdelhamid

results of Halcox et al . who demonstrated that systemic endothelial function was related to progression of preclinical carotid arterial disease and was more strongly related to CIMT changes than traditional risk factors ( 18 ). In a meta-analysis of 27

Open access

Mauricio Alvarez, Oswaldo Rincón Sierra, Ginna Saavedra, and Sergio Moreno

, 19 , 20 , 21 ). A recently published meta-analysis found that the use of metformin is a risk factor for vitamin B12 deficiency in diabetic patients ( 22 ). Previous studies have indicated prevalence rates of vitamin B12 deficiency ranging from 5 to