Search Results

You are looking at 21 - 30 of 54 items for :

  • "multiple endocrine neoplasia" x
  • All content x
Clear All
Open access

Kosmas Daskalakis, Marina Tsoli, Anna Angelousi, Evanthia Kassi, Krystallenia I Alexandraki, Denise Kolomodi, Gregory Kaltsas, and Anna Koumarianou

included in the study, 74 had sporadic tumours and 8 familial NENs in the context of multiple endocrine neoplasia type 1 (MEN 1) syndrome. Based on primary tumour location, cases were grouped into small intestinal NENs ( n  = 21), pancreatic NENs (PanNENs

Open access

Caojie Liu, Qingguo Lv, Xinlei Chen, Guangcheng Ni, Liru Hu, Nanwei Tong, and Yuwei Zhang

crisis, % 93 (62.4%) 166 (48.4%) 9 4 0.56 Multiple endocrine neoplasia II, % 7 (4.7%) 23 (6.7%) 1 4 0.68 Pathological type 1/2/3/4/5* 129/18/2/0/0 279/21/16/12/15 11/0/0/0/0 21/0/0/1/1 0.63 * 1

Open access

Kjell Oberg, Eric Krenning, Anders Sundin, Lisa Bodei, Mark Kidd, Margot Tesselaar, Valentina Ambrosini, Richard P Baum, Matthew Kulke, Marianne Pavel, Jaroslaw Cwikla, Ignat Drozdov, Massimo Falconi, Nicola Fazio, Andrea Frilling, Robert Jensen, Klaus Koopmans, Tiny Korse, Dik Kwekkeboom, Helmut Maecke, Giovanni Paganelli, Ramon Salazar, Stefano Severi, Jonathan Strosberg, Vikas Prasad, Aldo Scarpa, Ashley Grossman, Annemeik Walenkamp, Mauro Cives, Irene Virgolini, Andreas Kjaer, and Irvin M Modlin

to be defined. Mutations in the ATRX/DAXX pathways were not considered major indicators of clinical outcome, and it was agreed that they should not be routinely assessed in pancreatic NENs. In patients with multiple endocrine neoplasia type I (MEN1

Open access

M Ingenwerth, T Brandenburg, D Führer-Sakel, M Goetz, F Weber, H Dralle, H-U Schildhaus, K W Schmid, and S Theurer

thyroid cancer-associated deaths ( 1 , 2 ). They can occur either as part of hereditary syndromes (<30% of all MTC) in multiple endocrine neoplasias (MEN) 2A or 2B with germline mutations in the RET proto-oncogene or as sporadic tumors with approximately

Open access

Paula Bruna Araujo, Leandro Kasuki, Carlos Henrique de Azeredo Lima, Liana Ogino, Aline H S Camacho, Leila Chimelli, Márta Korbonits, and Monica R Gadelha

familial pituitary adenomas either isolated (FIPA and X-linked acro gigantism) or as a component of other genetic syndromes (e.g. multiple endocrine neoplasia types 1 (MEN1) and 4 (MEN4), Carney complex, familial pheochromocytoma

Open access

Maria Mizamtsidi, Constantinos Nastos, George Mastorakos, Roberto Dina, Ioannis Vassiliou, Maria Gazouli, and Fausto Palazzo

with syndromic and hereditary disease, like multiple endocrine neoplasia type 1 (MEN1), type 2A (MEN2A), type 4 (MEN4) and hyperparathyroidism jaw-tumor syndrome (HPT-JS) or the non-syndromic familial form of the disease, the familial isolated primary

Open access

Adrian F Daly, David A Cano, Eva Venegas-Moreno, Patrick Petrossians, Elena Dios, Emilie Castermans, Alvaro Flores-Martínez, Vincent Bours, Albert Beckers, and Alfonso Soto-Moreno

MacroAd Yes (2) Yes WT; MLPA normal WT; MLPA normal AIP, aryl hydrocarbon receptor interacting protein; DA, dopamine agonist; FIPA, familial isolated pituitary adenoma; MacroAd, macroadenoma; MEN1, multiple endocrine neoplasia type 1

Open access

Adrian F Daly, Liliya Rostomyan, Daniela Betea, Jean-François Bonneville, Chiara Villa, Natalia S Pellegata, Beatrice Waser, Jean-Claude Reubi, Catherine Waeber Stephan, Emanuel Christ, and Albert Beckers

syndromes such as multiple endocrine neoplasia type 1 (MEN1), McCune–Albright Syndrome (MAS), Carney complex, and the emerging pheochromocytoma-paraganglioma-pituitary adenoma association (3PA) ( 7 ). Mutations in the aryl hydrocarbon receptor interacting

Open access

Benjamin G Challis, Andrew S Powlson, Ruth T Casey, Carla Pearson, Brian Y Lam, Marcella Ma, Deborah Pitfield, Giles S H Yeo, Edmund Godfrey, Heok K Cheow, V Krishna Chatterjee, Nicholas R Carroll, Ashley Shaw, John R Buscombe, and Helen L Simpson

, and associated with multiple endocrine neoplasia (MEN)-1 ( 1 ). Although single-copy deletion and somatic mutations in Menin have been identified in some sporadic insulinoma, it is now recognised that a recurrent somatic mutation in the transcription

Open access

Felix Haglund, Gustaf Rosin, Inga-Lena Nilsson, C Christofer Juhlin, Ylva Pernow, Sophie Norenstedt, Andrii Dinets, Catharina Larsson, Johan Hartman, and Anders Höög

Lubensky IA Liotta LA . Positional cloning of the gene for multiple endocrine neoplasia-type 1 . Science 1997 276 404 – 407 . ( doi:10.1126/science.276.5311.404 ). 8 Lemmens I Van de Ven W Kas J Zhang CX Giraud S Wautot V Buisson