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Kennett Sprogøe, Eva Mortensen, David B Karpf, and Jonathan A Leff

critical for a wide variety of bodily functions, including adiposity regulation, glucose control, lipid metabolism, and cognition ( 1 , 2 , 3 ). These effects are mediated both directly by GH and indirectly by insulin-like growth factor (IGF-1). In target

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Lianghui You, Yan Wang, Yao Gao, Xingyun Wang, Xianwei Cui, Yanyan Zhang, Lingxia Pang, Chenbo Ji, Xirong Guo, and Xia Chi

demonstrated that the activation of thermogenesis in fat could produce a healthier metabolic phenotype with traits such as whole-body energy metabolism, improved glucose homeostasis, and weight loss ( 2 , 3 ). Moreover, functional BAT was discovered in adult

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Julie M Silverstein

-010-0281-0 ). 6 Nachtigall L Delgado A Swearingen B Lee H Zerikly R Klibanski A . Changing patterns in diagnosis and therapy of acromegaly over two decades . Journal of Clinical Endocrinology and Metabolism 2008 93 2035 – 2041 . ( doi:10

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Mirjana Kocova, Vesna Janevska, and Violeta Anastasovska

hyperplasia due to 21-hydroxylase deficiency . Annals of Pediatric Endocrinology and Metabolism 2016 21 1 – 6 . ( https://doi.org/10.6065/apem.2016.21.1.1 ) 10.6065/apem.2016.21.1.1 2 White PC Speiser PW . Congenital adrenal hyperplasia due to 21

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Aldo Bonaventura, Fabrizio Montecucco, and Franco Dallegri

Wallace TM Rasmussen AK Jørgensen HV Matthews DR Hougaard P Thorsteinsson B . Severe hypoglycaemia in 1076 adult patients with type 1 diabetes: influence of risk markers and selection . Diabetes/Metabolism Research and Reviews 2004 20

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Bjørn O Åsvold, Valdemar Grill, Ketil Thorstensen, and Marit R Bjørgaas

(efavirenz) that may induce CYP3A4 and thereby accelerate dexamethasone metabolism; in this subject, plasma dexamethasone was 2.3 nmol/l, and posttest cortisol was 408 nmol/l in plasma and 10 nmol/l in saliva. None of the women reported use of the

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Esben S Lauritzen, Nikolaj Rittig, Ermina Bach, Niels Møller, and Mette Bjerre

regain normal function ( 18 ). Considering the reducing effects of FGF21 on lipid and glucose metabolism, FGF21 is likely to play an important role in the metabolic reactions to the APR. Whether FGF21 increases counter-regulatory to the metabolic

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V Kenan Çelik, Sercan Kapancık, Turgut Kaçan, Selen Baloglu Kaçan, Serkan Kapancık, and Hasan Kılıçgün

showing that changes in arginine metabolism are important in a variety of diseases such as sepsis, cancer and type II diabetes also support our findings ( 27 , 28 , 29 ). In another study supporting our findings, it was suggested that arginine

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P R van Dijk, S J J Logtenberg, K H Groenier, N Kleefstra, H J G Bilo, and H J Arnqvist

Introduction Insulin and insulin-like growth factor 1 (IGF1) are structurally and functionally closely related peptides. IGF1, mainly synthesized in the liver after stimulation of the GH receptor, plays a central role in cell metabolism and growth

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Ingeborg Brønstad, Lars Breivik, Paal Methlie, Anette S B Wolff, Eirik Bratland, Ingrid Nermoen, Kristian Løvås, and Eystein S Husebye

. Journal of Clinical Endocrinology and Metabolism 2010 95 4133 – 4160 . ( doi:10.1210/jc.2009-2631 ). 2 Wedell A . An update on the molecular genetics of congenital adrenal hyperplasia: diagnostic and therapeutic aspects . Journal of Pediatric