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Peter Ergang, Anna Mikulecká, Martin Vodicˇka, Karla Vagnerová, Ivan Mikšík, and Jirˇí Pácha

determine (i) whether social stress influences the local metabolism of glucocorticoids in primary and secondary lymphoid organs, i.e. in the structures where immune cells undergo development and activation and (ii) whether there is any strain predisposition

Open access

Ling Zhou, Zhexin Ni, Wen Cheng, Jin Yu, Shuai Sun, Dongxia Zhai, Chaoqin Yu, and Zailong Cai

IR, promoting the development of PCOS ( 2 ). The interrelation between gut microbiota and PCOS is attracting increased attention. Compared with healthy women, Lindheim et al . ( 3 ) found that the abundance of ML615J-28 and 124-7 from phylum

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Agnieszka Kosowska, Enrique Gallego-Colon, Wojciech Garczorz, Agnieszka Kłych-Ratuszny, Mohammad Reza F Aghdam, Michał Woz´niak, Andrzej Witek, Agnieszka Wróblewska-Czech, Anna Cygal, Jerzy Wojnar, and Tomasz Francuz

.113 ) 10.1038/modpathol.2014.113 9 Lengyel E . Ovarian cancer development and metastasis . American Journal of Pathology 2010 177 1053 – 1064 . ( doi:10.2353/ajpath.2010.100105 ) 10.2353/ajpath.2010.100105 10 Weidle UH Birzele F

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Satoshi Inoue, Taichi Mizushima, Hiroki Ide, Guiyang Jiang, Takuro Goto, Yujiro Nagata, George J Netto, and Hiroshi Miyamoto

treatment such as radical cystectomy with neoadjuvant/adjuvant chemotherapy. Accordingly, identifying key molecules/pathways responsible for the development and/or growth of urothelial tumor may offer novel targeted therapy that improves patient outcomes

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Agnieszka Adamska, Aleksandra Maria Polak, Anna Krentowska, Agnieszka Łebkowska, Justyna Hryniewicka, Monika Leśniewska, and Irina Kowalska

dysfunction and characteristic image of the ovaries in the ultrasound ( 2 ). A lot of data indicated that insulin resistance is a key factor in the development of metabolic disturbances in PCOS, for example, obesity, type 2 diabetes (T2D), cardiovascular

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Elizaveta Mamedova, Natalya Mokrysheva, Evgeny Vasilyev, Vasily Petrov, Ekaterina Pigarova, Sergey Kuznetsov, Nikolay Kuznetsov, Liudmila Rozhinskaya, Galina Melnichenko, Ivan Dedov, and Anatoly Tiulpakov

( 5 ). PHPT development at an early age is suspicious for hereditary causes, but whether routine mutational analysis among young patients with PHPT, for example for MEN1 mutations, is needed and under what age it is advisable remains controversial

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Christin Krause, Martina Grohs, Alexander T El Gammal, Stefan Wolter, Hendrik Lehnert, Oliver Mann, Jens Mittag, and Henriette Kirchner

, ranging from steatosis with normal hepatic function to nonalcoholic steatohepatitis (NASH) and further to cirrhotic NASH and even hepatocellular carcinoma (for review see ( 1 )). Several endocrine pathways are known to contribute to the development and

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H A Booij, W D C Gaykema, K A J Kuijpers, M J M Pouwels, and H M den Hertog

stalk at the time of injury ( 4 ). This, and other secondary mechanisms after TBI, such as hypotension, hypoxia and raised intracranial pressure might be responsible for the development of PD ( 5 ). The same concept might be applied in part to brain

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L M Mongioì, R A Condorelli, S La Vignera, and A E Calogero

3912 – 3922 . ( ) 10.1210/jc.2007-0685 14 Løvås K Curran S Oksnes M Husebye ES Huppert FA Chatterjee VK. Development of a disease-specific quality of life questionnaire in Addison’s disease . Journal of Clinical

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A Daniel Bird, Spencer Greatorex, David Reser, Gareth G Lavery, and Timothy J Cole

all stages of ovarian follicle development ( Fig. 5A and D ). Also shown are negative controls with no primary antibody (panel B) and an immunizing peptide, pre-incubation control (panel C). The mouse ovary, that should not express a HSD1L protein