with reproducibility and accurate delineation of metastatic disease, particularly extra-liver disease. The development of new lesions is probably the most powerful indicator of disease progression. Functional imaging with somatostatin receptor
Kjell Oberg, Eric Krenning, Anders Sundin, Lisa Bodei, Mark Kidd, Margot Tesselaar, Valentina Ambrosini, Richard P Baum, Matthew Kulke, Marianne Pavel, Jaroslaw Cwikla, Ignat Drozdov, Massimo Falconi, Nicola Fazio, Andrea Frilling, Robert Jensen, Klaus Koopmans, Tiny Korse, Dik Kwekkeboom, Helmut Maecke, Giovanni Paganelli, Ramon Salazar, Stefano Severi, Jonathan Strosberg, Vikas Prasad, Aldo Scarpa, Ashley Grossman, Annemeik Walenkamp, Mauro Cives, Irene Virgolini, Andreas Kjaer, and Irvin M Modlin
Xuan Luo, Tingting Zheng, Chaoming Mao, Xin Dong, Xiao Mou, Chengcheng Xu, Qingyan Lu, Baocui Liu, Shengjun Wang, and Yichuan Xiao
. Importantly, IL-1β was also highly expressed in the tissues of the HT patients, suggesting that there is an interaction between MRP14 and IL-1β in the development of HT. Notably, our results showed that IL-1β induced the expression of not only chemokines in
Juan Carlos Juárez-Cruz, Miriam Daniela Zuñiga-Eulogio, Monserrat Olea-Flores, Eduardo Castañeda-Saucedo, Miguel Ángel Mendoza-Catalán, Carlos Ortuño-Pineda, Ma Elena Moreno-Godínez, Sócrates Villegas-Comonfort, Teresita Padilla-Benavides, and Napoleón Navarro-Tito
, which further enhances the predisposition of developing breast tumors ( 4 ). Among these molecules, leptin is one of the most important adipokines involved in the development and progression of mammary tumors ( 5 ). Leptin is a hormone with a molecular
Fabian Eichelmann, Cornelia Weikert, Romina di Giuseppe, Ronald Biemann, Berend Isermann, Matthias B Schulze, Heiner Boeing, and Krasimira Aleksandrova
-scale prospective population-based studies exist to support or refute generated hypothesis on chemerin involvement in disease development. Important prerequisite for planning biomarker assessment in a prospective study is the assessment of whether single biomarker
Selina Mäkinen, Yen H Nguyen, Paulina Skrobuk, and Heikki A Koistinen
to ROS production ( 18 ), we next analysed if development of insulin resistance of glucose uptake is related to ROS. Human myotubes were exposed for 12 h to palmitate, oleate or their combination. Mitochondrial ROS production was significantly
K L Gatford, G K Heinemann, S D Thompson, J V Zhang, S Buckberry, J A Owens, G A Dekker, C T Roberts, and on behalf of the SCOPE Consortium
Introduction The insulin-like growth factors (IGFs), IGF1 and IGF2, are important regulators of placental and foetal development, as well as postnatal growth and metabolism. In humans, circulating IGF1 peaks in adolescence and then falls with age
B Shahida, P Sahlstrand Johnson, R Jain, H Brorson, P Åsman, M Lantz, and T Planck
Introduction Autoimmune thyroid disease is a prerequisite for the development of Graves’ ophthalmopathy (GO), and both thyroid and orbital tissues are infiltrated by immunocompetent cells. The thyroid-stimulating hormone receptor (TSHR) acts
Stefano Mangiola, Ryan Stuchbery, Patrick McCoy, Ken Chow, Natalie Kurganovs, Michael Kerger, Anthony Papenfuss, Christopher M Hovens, and Niall M Corcoran
–20%, respectively ( 8 , 10 ). The promotion of an obese-like phenotype by androgen deprivation is highly clinically relevant, as obesity (expressed as BMI) is itself associated with the development of prostate cancer, post-prostatectomy biochemical failure and
Marloes Emous, Merel van den Broek, Ragnhild B Wijma, Loek J M de Heide, Gertjan van Dijk, Anke Laskewitz, Erik Totté, Bruce H R Wolffenbuttel, and André P van Beek
has been observed ( 36 ). This suggests that the development of hypoglycaemia unawareness cannot be attributed to a specific type of bariatric surgery. The discrepancy between the asymptomatic low blood sugars in our study and the development of
Melissa Braga, Zena Simmons, Keith C Norris, Monica G Ferrini, and Jorge N Artaza
Introduction Vitamin D is universally recognized for its classical effects on calcium regulation and phosphate homeostasis, in relation to bone development and maintenance ( 1 , 2 ). However, vitamin D deficiency has also been linked to the