Yuegui Wang
Yuegui Wang
Department of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
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Liwei Hong
Liwei Hong
Department of Nuclear Medicine, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
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Caiyun Yang
Caiyun Yang
Department of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
School of Clinical Medicine, Fujian Medical University, Fuzhou, Fujian, China
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School of Clinical Medicine, Fujian Medical University, Fuzhou, Fujian, China
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Guorong Lv
Guorong Lv
School of Clinical Medicine, Fujian Medical University, Fuzhou, Fujian, China
Quanzhou Medical College, Quanzhou, Fujian, China
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Quanzhou Medical College, Quanzhou, Fujian, China
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Kangjian Wang
Kangjian Wang
Department of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
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Xuepeng Huang
Xuepeng Huang
Department of Nuclear Medicine, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
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Haolin Shen
Haolin Shen
Department of Ultrasound, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China
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orbitopathy ( 5 ). Therapies for GD include antithyroid drugs (ATDs), thyroidectomy, or radioactive iodine (RAI) therapy. ATD has only a 50% success rate for most patients after 1 year of treatment, and it may cause side effects such as agranulocytosis
Eugenie S Lim
Eugenie S Lim
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Shanty G Shah
Shanty G Shah
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Mona Waterhouse
Mona Waterhouse
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Scott Akker
Scott Akker
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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William Drake
William Drake
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Nick Plowman
Nick Plowman
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Daniel M Berney
Daniel M Berney
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Polly Richards
Polly Richards
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Ashok Adams
Ashok Adams
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Ewa Nowosinska
Ewa Nowosinska
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Carmel Brennan
Carmel Brennan
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
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Maralyn Druce
Maralyn Druce
Barts Health NHS Trust, Barts and the London School of Medicine and Dentistry, London, UK
Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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Barts and the London School of Medicine and Dentistry, QMUL, London, UK
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received either ‘traditional’ or low-dose ablation. Prior to therapy, patients were advised to eat a diet low in iodine for 1–2 weeks and all doses were administered under conditions of high TSH, predominantly achieved with recombinant TSH. Patients were
Norra Kwong
Norra Kwong
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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Ellen Marqusee
Ellen Marqusee
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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Michael S Gordon
Michael S Gordon
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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P Reed Larsen
P Reed Larsen
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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Jeffrey R Garber
Jeffrey R Garber
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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Matthew I Kim
Matthew I Kim
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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Erik K Alexander
Erik K Alexander
Division of Endocrinology, Endocrine Division, Hypertension and Diabetes, Thyroid Section, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Avenue Boston, Massachusetts 02115, USA
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radioactive iodine (RAI) ( 131 I) ablation, followed by thyroid hormone suppression therapy (6, 7, 8, 9) . Though there may be benefits to this approach, especially for patients with advanced disease, increasing evidence confirms that such a standardized
Adriano N Cury
Adriano N Cury
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Verônica T Meira
Verônica T Meira
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Osmar Monte
Osmar Monte
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Marília Marone
Marília Marone
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Nilza M Scalissi
Nilza M Scalissi
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Cristiane Kochi
Cristiane Kochi
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Luís E P Calliari
Luís E P Calliari
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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Carlos A Longui
Carlos A Longui
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
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surgical procedure that can effect complications, depending on the surgeon's experience (1) . Radioactive iodine (RAI) therapy has been used frequently, especially in the USA (7) , as an alternative first-line therapy to surgery and ATDs. The incidence
Keiko Ohkuwa
Keiko Ohkuwa
Department of Surgery, Ito Hospital, Tokyo, Japan
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Kiminori Sugino
Kiminori Sugino
Department of Surgery, Ito Hospital, Tokyo, Japan
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Mitsuji Nagahama
Mitsuji Nagahama
Department of Surgery, Ito Hospital, Tokyo, Japan
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Wataru Kitagawa
Wataru Kitagawa
Department of Surgery, Ito Hospital, Tokyo, Japan
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Kenichi Matsuzu
Kenichi Matsuzu
Department of Surgery, Ito Hospital, Tokyo, Japan
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Akifumi Suzuki
Akifumi Suzuki
Department of Surgery, Ito Hospital, Tokyo, Japan
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Chisato Tomoda
Chisato Tomoda
Department of Surgery, Ito Hospital, Tokyo, Japan
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Kiyomi Hames
Kiyomi Hames
Department of Surgery, Ito Hospital, Tokyo, Japan
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Junko Akaishi
Junko Akaishi
Department of Surgery, Ito Hospital, Tokyo, Japan
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Chie Masaki
Chie Masaki
Department of Surgery, Ito Hospital, Tokyo, Japan
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Koichi Ito
Koichi Ito
Department of Surgery, Ito Hospital, Tokyo, Japan
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patients with DTC and is predominantly observed in the lungs and bone ( 3 , 4 , 5 , 6 ). When treating metastatic tumors of differentiated thyroid carcinoma, a favorable prognosis can be expected after radioactive iodine (RAI) therapy after total
Guoquan Zhu
Guoquan Zhu
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China
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Yuying Deng
Yuying Deng
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China
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Liqin Pan
Liqin Pan
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China
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Wei Ouyang
Wei Ouyang
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China
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Huijuan Feng
Huijuan Feng
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China
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Juqing Wu
Juqing Wu
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China
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Pan Chen
Pan Chen
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China
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Jing Wang
Jing Wang
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China
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Yanying Chen
Yanying Chen
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China
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Jiaxin Luo
Jiaxin Luo
Department of Nuclear Medicine, Zhujiang Hospital of Southern Medical University, Guangzhou, China
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to that of the wild-type group. One possible reason for this unexpected finding might be that all patients received postsurgical RAI therapy in our study. According to previous research, radioactive iodine (RAI) therapy, as an important adjuvant
Lian Duan
Lian Duan
Department of Nuclear Medicine, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, China
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Han-Yu Zhang
Han-Yu Zhang
Changzhi Medical College, Changzhi, Shanxi, China
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Min Lv
Min Lv
Department of Nuclear Medicine, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, China
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Han Zhang
Han Zhang
Changzhi Medical College, Changzhi, Shanxi, China
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Yao Chen
Yao Chen
Changzhi Medical College, Changzhi, Shanxi, China
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Ting Wang
Ting Wang
Department of Nuclear Medicine, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, China
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Yan Li
Yan Li
Department of Nuclear Medicine, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, China
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Yan Wu
Yan Wu
Department of Clinical Laboratory, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China
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Junfeng Li
Junfeng Li
Department of Radiology, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, China
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Kefeng Li
Kefeng Li
School of Medicine, University of California, San Diego, California, USA
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validation set. RAI, radioiodine therapy; ROC, receiver operator characteristic curve; HT, hypothyroidism; NC, the normal control group; AST, aspartate aminotransferase; TRAb, thyrotropin-receptor antibodies; 24-h RAIU, radioactive iodine uptake at 24 h; TMA
Danuta Gąsior-Perczak
Danuta Gąsior-Perczak
Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland
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Iwona Pałyga
Iwona Pałyga
Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland
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Monika Szymonek
Monika Szymonek
Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland
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Artur Kowalik
Artur Kowalik
Department of Molecular Diagnostics, Holycross Cancer Centre, Kielce, Poland
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Agnieszka Walczyk
Agnieszka Walczyk
Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland
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Janusz Kopczyński
Janusz Kopczyński
Department of Surgical Pathology, Holycross Cancer Centre, Kielce, Poland
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Katarzyna Lizis-Kolus
Katarzyna Lizis-Kolus
Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland
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Anna Słuszniak
Anna Słuszniak
Laboratory of Tumor Markers, Holycross Cancer Centre, Kielce, Poland
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Janusz Słuszniak
Janusz Słuszniak
Department of Surgical Oncology, Holycross Cancer Centre, Kielce, Poland
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Tomasz Łopatyński
Tomasz Łopatyński
Department of Surgery, Oncology Center of Lublin Land, Lublin, Poland
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Ryszard Mężyk
Ryszard Mężyk
Cancer Epidemiology, Holycross Cancer Centre, Kielce, Poland
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Stanisław Góźdź
Stanisław Góźdź
Oncology Clinic, Holycross Cancer Centre, Kielce, Poland
The Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland
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The Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland
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Aldona Kowalska
Aldona Kowalska
Endocrinology Clinic, Holycross Cancer Centre, Kielce, Poland
The Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland
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The Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland
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many cases, lobectomy (L) is sufficient as surgical treatment and radioactive iodine ( 131 I) therapy is often unnecessary ( 7 ). Much attention has been paid to personalizing the way the disease is monitored; however, research efforts have focused on
Marek Niedziela
Marek Niedziela
Department of Pediatric Endocrinology and Rheumatology, Institute of Pediatrics, Karol Jonscher’s Clinical Hospital, Poznan University of Medical Sciences, Poznan, Poland
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.1530/EC-12-0049 ) 40 Kaplowitz PB Jiang J Vaidyanathan P . Radioactive iodine therapy for pediatric Graves’ disease: a single-center experience over a 10-year period . Journal of Pediatric Endocrinology and Metabolism 2020 33 383 – 389 . ( https
Klaudia Zajkowska
Klaudia Zajkowska
Endocrinology, Holycross Cancer Centre, Kielce, Poland
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Janusz Kopczyński
Janusz Kopczyński
Surgical Pathology, Holycross Cancer Centre, Kielce, Poland
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Stanisław Góźdź
Stanisław Góźdź
Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland
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Aldona Kowalska
Aldona Kowalska
Endocrinology, Holycross Cancer Centre, Kielce, Poland
Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland
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Faculty of Health Sciences, Jan Kochanowski University, Kielce, Poland
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inclusion and exclusion criteria has an extremely indolent clinical behaviour, even when treated conservatively with lobectomy and without radioactive iodine therapy. Nevertheless, it cannot be considered as a benign lesion. The risk of adverse outcomes
