(the therapeutic corticosteroid of choice at the time) was soon applied in the management of meperidine and morphine withdrawal symptoms in men (5) , apparently with beneficial effects, while Lovell associated alcoholism and drug addiction with
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Lesley A Hill, Zeynep Sumer-Bayraktar, John G Lewis, Eva Morava, Morten Thaysen-Andersen, and Geoffrey L Hammond
Introduction Corticosteroid-binding globulin (CBG) transports steroids in the blood and regulates their access to tissues and cells ( 1 , 2 ). Crystal structure analyses show that CBG contains a single hydrophobic steroid-binding site ( 3
Muriel Houang, Thao Nguyen-Khoa, Thibaut Eguether, Bettina Ribault, Séverine Brabant, Michel Polak, Irène Netchine, and Antonin Lamazière
discriminant test, we questioned the mother regarding her medication. The mother happened to be on nasal spray corticosteroids (triamcinolone) throughout the pregnancy and during the neonatal period while she was breastfeeding. This significantly lowered all
Britt J van Keulen, Michelle Romijn, Bibian van der Voorn, Marita de Waard, Michaela F Hartmann, Johannes B van Goudoever, Stefan A Wudy, Joost Rotteveel, and Martijn J J Finken
/kg/day). Outcomes were: (1) cortisol excretion rate (µg/kg/day), (2) the sum of all glucocorticoid metabolites or corticosteroid excretion rate (µg/kg/day), and (3) the ratio of 11-hydroxy (11-OH)/11-oxoandrostenedione (11-OXO) metabolites, as an estimate of 11B
Ruth Percik, Sherwin Criseno, Safwaan Adam, Kate Young, and Daniel L Morganstein
glucocorticoids such as creams, inhalers or nasal sprays, including those used for non-ICPI-related toxicity (e.g. asthma). Where potentially suppressive doses of corticosteroids have been used ( 27 ), a careful weaning protocol should be followed (such as that in
Jana Ernst, Katharina Gert, Frank Bernhard Kraus, Ulrike Elisabeth Rolle-Kampczyk, Martin Wabitsch, Faramarz Dehghani, and Kristina Schaedlich
conditions, androgens (androstenedione, androsterone, testosterone, dihydrotestosterone, etiocholanolone) and corticosteroids (corticosterone, aldosterone, 11-deoxycortisol, cortisol, cortisone) increased during adipogenesis. Furthermore, an androstenedione
Pablo Abellán-Galiana, Carmen Fajardo-Montañana, Pedro Riesgo-Suárez, Marcelino Pérez-Bermejo, Celia Ríos-Pérez, and José Gómez-Vela
specific treatment for hypercortisolism (ketoconazole and/or cabergoline) was suspended before surgery (at least 1 week), avoiding the use of corticosteroids in the surgical phase. Imaging studies using neuronavigation protocols were made, together with a
Athanasios D Anastasilakis, Marina Tsoli, Gregory Kaltsas, and Polyzois Makras
-up can be recommended. Intralesional corticosteroid injection, low-dose irradiation or surgical curettage have been used. However, complete surgical excision is not always recommended as it may sometimes increase the healing time and/or leave a large bone
Petar Milovanovic and Björn Busse
osteocyte death also occurs due to hormonal reasons, such as estrogen deficiency or corticosteroid excess ( 38 , 39 , 45 ). Moreover, osteocyte death may be caused by mechanical factors ( 36 , 46 ), but the relationship between mechanical loading and
Trevor Lewis, Eva Zeisig, and Jamie E Gaida
and associated metabolic conditions, such as insulin resistance ( 5 ), diabetes ( 6 ), hypercholesterolaemia ( 7 ), statins ( 8 ), abdominal fat ( 9 ), the sympathetic nervous system ( 10 , 11 ), and corticosteroid use ( 12 ). Glucocorticoids are a
