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in combination with androgen receptor signaling inhibitors, radiotherapy and/or chemotherapy ( 6 ). The purpose of ADT is to suppress the major driver of PCa tumor growth testosterone as much as possible ( 7 ). The suppression of testosterone causes
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2020 10 18222. ( https://doi.org/10.1038/s41598-020-75309-w ) 26 Estumano DP Ferreira LO Bezerra PAL da Silva MCP Jardim GC Santos GFS Gustavo KS Mattos BG Ramos JAB Jóia de Mello V Alteration of testosterone levels changes brain
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enough. Thus, more studies are needed to explore SII as an early marker of osteoporosis in postmenopausal women. The association between SII and testosterone may differ by menopausal status since we observed significant associations in postmenopausal