Waikato Clinical Campus, University of Auckland, Hamilton, New Zealand
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–3 weeks for mouth ulcers but reported no oral, inhaled or parenteral corticosteroid use. On examination, the patient was hypertensive (BP 154/74 mmHg), euphoric and grossly oedematous with bilateral pitting oedema to the mid-shins and mild facial oedema
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.1% celiac disease, and 0.6% Turner syndrome. In the cohort of children with treated SH, the most prescribed co-medications were antibacterials for systemic use (92.5%), antiasthmatics (71.4%), corticosteroids (39.4%) and antihistamines (30.3%) for systemic
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corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth . Cochrane Database of Systematic Reviews 2006 CD004454 . ( doi:10.1002/14651858.CD004454.pub2 ). 17 Heckmann M Hartmann MF Kampschulte B Gack H Bodeker RH
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. Discriminatory features included easy bruising, facial plethora, proximal muscle weakness, and/or striae (especially if reddish purple and >1 cm wide). Patients with a history of exogenous corticosteroid intake, pregnant women, women using oral contraceptive (OC
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Isala, Department of Internal Medicine, Zwolle, The Netherlands
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Langerhans Medical Research group, Zwolle, The Netherlands
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Department of General Practice, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Langerhans Medical Research group, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Isala, Department of Internal Medicine, Zwolle, The Netherlands
Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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. Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma . Journal of Clinical Endocrinology and Metabolism 1981 53 58 – 68 . ( doi:10.1210/jcem-53
The Leicester Diabetes Centre, University Hospitals of Leicester NHS Trust, Leicester General Hospital, Leicester, UK
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Department of Diabetes and Endocrinology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester, UK
Diabetes and Endocrinology Department, Kettering General Hospital NHS Foundation Trust, Kettering, UK
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Diabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK
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Diabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK
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Diabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK
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Diabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK
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The Leicester Diabetes Centre, University Hospitals of Leicester NHS Trust, Leicester General Hospital, Leicester, UK
Diabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK
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The Leicester Diabetes Centre, University Hospitals of Leicester NHS Trust, Leicester General Hospital, Leicester, UK
Diabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK
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were eligible. Exclusion criteria were pregnancy, diabetes, use of corticosteroids, a disabling physical or mental condition and inability to speak English. The SUCCESS study recruited a total of 161 participants and for the purpose of this study
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Division of Medicine, Akershus University Hospital, Lørenskog, Norway
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Department of Clinical Medicine, University of Bergen, Bergen, Norway
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K.G. Jebsen-Center for Autoimmune Diseases, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway
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K.G. Jebsen-Center for Autoimmune Diseases, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway
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–MS/MS methods are superior to immunoassays in monitoring patients with 21OHD on corticosteroid replacement therapy as they are more specific and can be multiplexed. Immunoassays seem to overestimate high concentrations of 17OHP and androstenedione considerably
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accompanied by excessive secretion of corticosteroids or adrenomedullary hormones ( 9 ). It has been suggested that a routine examination of adrenal endocrine function be performed before surgery to determine the nature of the incidental adrenal tumours, to
The Clatterbridge Cancer Centre, Wirral, UK
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Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK
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reversible with corticosteroid containing immunosuppression, the endocrinopathies appear to be irreversible and, in the majority of cases, require lifelong replacement therapy ( 11 ). Thyroid dysfunction reported within metastatic malignant melanoma
Center for Primary Health Care Research, Lund University, Malmö, Sweden
GeneWerk GmbH, Heidelberg, Germany
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Departments of Family Medicine and Community Health, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Center for Community-based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University, Shimane, Japan
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Departments of Family Medicine and Community Health, Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Center for Community-based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University, Shimane, Japan
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Center for Primary Health Care Research, Lund University, Malmö, Sweden
Hopp Children’s Cancer Center (KiTZ), Heidelberg, Germany
Division of Pediatric Neurooncology, German Cancer Research Centre (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany
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Center for Primary Health Care Research, Lund University, Malmö, Sweden
Division of Cancer Epidemiology, German Cancer Research Centre (DKFZ), Heidelberg, Germany
Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, Pilsen, Czech Republic
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Introduction Addison’s disease (AD) is an autoimmune disease (AID) characterized by a gradual autoantibody destruction of the adrenal cortex with resulting impaired production of corticosteroids and mineralocorticoids ( 1 ). Most patients