Jiwen Yang
Jiwen Yang
Department of Nuclear Medicine, Yijishan Hospital of Wannan Medical College, Wuhu City, Anhui Province, China
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Yayin Huang
Yayin Huang
Department of Clinical Laboratory, The Second People’s Hospital of Wuhu, Wuhu City, Anhui Province, China
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Bohan Dong
Bohan Dong
Department of Biochemistry and Molecular Biology, Wannan Medical College, Wuhu City, Anhui Province, China
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Yunhai Dai
Yunhai Dai
Department of Nuclear Medicine, Yijishan Hospital of Wannan Medical College, Wuhu City, Anhui Province, China
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in vitro . Introduction Thyroid cancer is a common endocrine malignant cancer ( 1 ). The survival of patients with thyroid cancer has improved with the combined therapy of surgery and radioactive iodine (RAI) therapy. However, the
Wei Sun
Wei Sun
Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China
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Boyuan Zheng
Boyuan Zheng
Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China
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Zhihong Wang
Zhihong Wang
Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China
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Wenwu Dong
Wenwu Dong
Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China
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Yuan Qin
Yuan Qin
Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China
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Hao Zhang
Hao Zhang
Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, Liaoning Province, China
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studies have reported benefits of PCLND in patients with cN0. For example, PCLDN can help to accurately diagnose tumor-node-metastasis (TNM) staging, help decide on the use of thyroid-stimulating hormone (TSH) suppression therapy or radioactive iodine (RAI
Changjiao Yan
Changjiao Yan
Department of Thyroid, Breast and Vascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi, China
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Meiling Huang
Meiling Huang
Department of Thyroid, Breast and Vascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi, China
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Xin Li
Xin Li
Department of Thyroid, Breast and Vascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi, China
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Ting Wang
Ting Wang
Department of Thyroid, Breast and Vascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi, China
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Rui Ling
Rui Ling
Department of Thyroid, Breast and Vascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi, China
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. Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial . Lancet 2014 384 . ( https://doi.org/10.1016/S0140-6736(14)60421-9 ) 24768112
Katerina Saltiki
Katerina Saltiki
Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece
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Elli Anagnostou
Elli Anagnostou
Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece
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George Simeakis
George Simeakis
Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece
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Sofia Kouki
Sofia Kouki
Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece
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Anastasia Angelopoulou
Anastasia Angelopoulou
Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece
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Leda Sarika
Leda Sarika
Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece
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Alexandra Papathoma
Alexandra Papathoma
Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece
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Maria Alevizaki
Maria Alevizaki
Endocrine Unit, Department of Medical Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece
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metastases from PTC were present in 2/9 patients (the tall cell variant and one classical PTC). Three out of 9 patients received Radioactive Iodine therapy. All patients are in remission concerning PTC. Of the non-exon 8 carriers, only 1/48 (2.1%) had
Wei Li
Wei Li
Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China
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Qing Huang
Qing Huang
Collage of Tourism and Service Management, Nankai University, Tianjin, People’s Republic of China
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Danyang Sun
Danyang Sun
Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China
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Guizhi Zhang
Guizhi Zhang
Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China
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Jian Tan
Jian Tan
Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China
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) ( 1 ). Through surgery and radioactive iodine ablation, most PTC patients have a good prognosis; however, a significant proportion of patients have persistent or recurrent disease and suffer from frequent recurrences or even distant metastases, leading
Bilal B Mughal
Bilal B Mughal
CNRS/UMR7221, Muséum National d’Histoire Naturelle, Sorbonne Universités, Paris, France
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Jean-Baptiste Fini
Jean-Baptiste Fini
CNRS/UMR7221, Muséum National d’Histoire Naturelle, Sorbonne Universités, Paris, France
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Barbara A Demeneix
Barbara A Demeneix
CNRS/UMR7221, Muséum National d’Histoire Naturelle, Sorbonne Universités, Paris, France
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chlorine and bromine. Interestingly, THs are the only complex halogenated (iodine) molecules produced by and necessary for vertebrate homeostasis, making TH physiology highly vulnerable to EDCs. Halogen-substituted phenolic moieties can mimic natural THs
