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Enrique Soto-Pedre, Paul J Newey, John S Bevan and Graham P Leese

of overall cancer or breast cancer. The prospective Nurses’ Health Study (NHS and NHSII) and a meta-analysis of 7 observational studies reported an increased risk of breast cancer of borderline significance, with the latter showing a relative risk of

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N Bergmann, F Gyntelberg and J Faber

Introduction The metabolic syndrome (MES) is a cluster of risk factors including male adiposity, dyslipidemia, reduced glucose tolerance and hypertension. MES is highly prevalent and increasing in most parts of the world (1) . A meta-analysis has

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Angelo Maria Patti, Kalliopi Pafili, Nikolaos Papanas and Manfredi Rizzo

-1713 ) 10.1210/jc.2004-1713 5 Bellamy L Casas JP Hingorani AD Williams D. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis . Lancet 2009 373 1773 – 1779 . ( https://doi.org/10.1016/S0140

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Christian Trummer, Stefan Pilz, Verena Schwetz, Barbara Obermayer-Pietsch and Elisabeth Lerchbaum

no treatment effect on pregnancy outcomes, the endometrial thickness was significantly higher in the vitamin D when compared to the placebo group. Meta-analyses A recent meta-analysis ( 63 ) including 16 studies involving 315 participants on

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Stavroula A Paschou, Eleni Palioura, Dimitrios Ioannidis, Panagiotis Anagnostis, Argyro Panagiotakou, Vasiliki Loi, Georgios Karageorgos, Dimitrios G Goulis and Andromachi Vryonidou

insulin resistance is positively associated with the degree of hyperandrogenism ( 5 , 6 ) and this was confirmed by a meta-analysis including 32 observational studies and 9556 women with PCOS in total. The higher the levels of androgens, the higher the

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V Kenan Çelik, Sercan Kapancık, Turgut Kaçan, Selen Baloglu Kaçan, Serkan Kapancık and Hasan Kılıçgün

.1002/1097-0142(195611/12)9:6<1127::AID-CNCR2820090610>3.0.CO;2-4 2 Hardefeldt PJ Edirimanne S Eslick GD . Diabetes increases the risk of breast cancer: a meta-analysis. Endocrine-Related Cancer 2012 19 793 – 803 . ( doi:10.1530/ERC-12-0242 ) 23035011 10.1530/ERC-12

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Renea A Taylor, Jennifer Lo, Natasha Ascui and Matthew J Watt

illustrated in a meta-analysis of 17 studies encompassing 3 569 926 prostate cancer patients. Although the findings of the individual studies contributing to these meta-analyses differed dramatically, overall, obesity was not significantly correlated with the

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Madalena von Hafe, João Sergio Neves, Catarina Vale, Marta Borges-Canha and Adelino Leite-Moreira

(CHD) events and mortality and atrial fibrillation ( 52 , 53 ). CHD mortality and atrial fibrillation are correlated with TSH levels, being higher with TSH under 0.10 mIU/L when compared with levels between 0.10 and 0.44 mIU/L ( 54 ). In a meta-analysis

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Malachi J McKenna, Barbara F Murray, Myra O'Keane and Mark T Kilbane

vitamin D supplements on bone mineral density: a systematic review and meta-analysis . Lancet 2014 383 146 – 155 . ( doi:10.1016/S0140-6736(13)61647-5 ). 11 Bolland MJ Grey A Gamble GD Reid IR . The effect of vitamin D supplementation on

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Aldo Bonaventura, Fabrizio Montecucco and Franco Dallegri

.1517/14740338.2012.694424 ). 78 Aroda VR Henry RR Han J Huang W DeYoung MB Darsow T Hoogwerf BJ . Efficacy of GLP-1 receptor agonists and DPP-4 inhibitors: meta-analysis and systematic review . Clinical Therapeutics 2012 34 1247 – 1258 . ( doi:10.1016/j