Helga Schultz
Helga Schultz
Department of Cardiology, Nephrology and Endocrinology, Nordsjællands Hospital, Hillerød, Denmark
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Svend Aage Engelholm
Svend Aage Engelholm
Department of Radiation Oncology, Rigshospitalet, Copenhagen, Denmark
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Eva Harder
Eva Harder
Department of Oncology and Palliation, Nordsjællands Hospital, Hillerød, Denmark
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Ulrik Pedersen-Bjergaard
Ulrik Pedersen-Bjergaard
Department of Cardiology, Nephrology and Endocrinology, Nordsjællands Hospital, Hillerød, Denmark
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Peter Lommer Kristensen
Peter Lommer Kristensen
Department of Cardiology, Nephrology and Endocrinology, Nordsjællands Hospital, Hillerød, Denmark
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and other variables (explanatory variables) in univariate and multivariate logistic regression models with corticosteroid-induced insulin-treated diabetes as dependent variable. Established risk factors for type 2 diabetes (sex, age, HbA1c, BMI, having
Ziting Liang
Ziting Liang
Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China
Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University, Shandong Institute of Respiratory Diseases, Jinan, China
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Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University, Shandong Institute of Respiratory Diseases, Jinan, China
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Mengge Yang
Mengge Yang
Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China
Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University, Shandong Institute of Respiratory Diseases, Jinan, China
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Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University, Shandong Institute of Respiratory Diseases, Jinan, China
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Changjuan Xu
Changjuan Xu
Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China
Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University, Shandong Institute of Respiratory Diseases, Jinan, China
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Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University, Shandong Institute of Respiratory Diseases, Jinan, China
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Rong Zeng
Rong Zeng
Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China
Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University, Shandong Institute of Respiratory Diseases, Jinan, China
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Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University, Shandong Institute of Respiratory Diseases, Jinan, China
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Liang Dong
Liang Dong
Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China
Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University, Shandong Institute of Respiratory Diseases, Jinan, China
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Department of Respiratory, Shandong Provincial Qianfoshan Hospital, Shandong University, The First Affiliated Hospital of Shandong First Medical University, Shandong Institute of Respiratory Diseases, Jinan, China
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increased risk of diabetes mellitus (DM) due to the sedentary lifestyle and adiposity of COPD patients, the inflammatory processes ( 2 ), and the treatment adverse effects associated with the use of high-dose corticosteroids ( 3 ). On the other hand
Paul-Martin Holterhus
Paul-Martin Holterhus
Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany
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Alexandra Kulle
Alexandra Kulle
Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany
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Anne-Marie Till
Anne-Marie Till
Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany
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Caroline Stille
Caroline Stille
Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany
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Tabea Lamprecht
Tabea Lamprecht
Department of Pediatrics I, Pediatric Endocrinology and Diabetology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian Albrechts University, CAU, Kiel, Germany
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Simon Vieth
Simon Vieth
Department of Pediatrics I, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Kiel and Christian-Albrechts-University, CAU, Kiel, Germany
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Melchior Lauten
Melchior Lauten
Department of Pediatrics, Pediatric Hematology and Oncology, University Hospital of Schleswig-Holstein, UKSH, Campus Lübeck, Germany
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Mahachoklertwattana P Vilaiyuk S Hongeng S & Okascharoen C . Suppression of adrenal function in children with acute lymphoblastic leukemia following induction therapy with corticosteroid and other cytotoxic agents . Journal of Pediatrics 2004 144 736 – 740
Arno Téblick
Arno Téblick
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Lies Langouche
Lies Langouche
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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Greet Van den Berghe
Greet Van den Berghe
Clinical Division and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium
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referred to as ‘relative adrenal insufficiency’, this state is nowadays labeled ‘critical illness-related corticosteroid insufficiency’ (CIRCI). In contrast to the occurrence of absolute adrenal failure in critically ill patients, neither a clear definition
Jaafar Jaafar
Jaafar Jaafar
Division of Endocrinology and Diabetology, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
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Eugenio Fernandez
Eugenio Fernandez
Department of Oncology, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
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Heba Alwan
Heba Alwan
Division of Endocrinology and Diabetology, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
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Jacques Philippe
Jacques Philippe
Division of Endocrinology and Diabetology, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
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corticosteroids) Nivolumab Hypothyroidism 2–3 month (range 1 day–16.6 month) Frequently stay in hypothyroidism with long-term THR Pembrolizumab Hyperthyroidism 1.4 month (range: 1 day to ~22 month) Three-fourths of affected patients 2
Paraskevi Kazakou
Paraskevi Kazakou
Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Stavroula A Paschou
Stavroula A Paschou
Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Theodora Psaltopoulou
Theodora Psaltopoulou
Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Maria Gavriatopoulou
Maria Gavriatopoulou
Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Eleni Korompoki
Eleni Korompoki
Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Katerina Stefanaki
Katerina Stefanaki
Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Fotini Kanouta
Fotini Kanouta
Department of Endocrinology, Alexandra Hospital, Athens, Greece
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Georgia N Kassi
Georgia N Kassi
Department of Endocrinology, Alexandra Hospital, Athens, Greece
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Meletios-Athanasios Dimopoulos
Meletios-Athanasios Dimopoulos
Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Asimina Mitrakou
Asimina Mitrakou
Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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secretion (11, 69) Drugs (corticosteroids, antivirals) (11, 34) Cahexia, muscle weakness, rhabdomyolysis lead to decreased insulin sensitivity (35, 36, 37) DPP4 potential SARS-CoV-2 receptor (70, 71, 72, 73) Hypothalamus and pituitary Possible
Jakub Supronik
Jakub Supronik
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
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Małgorzata Szelachowska
Małgorzata Szelachowska
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
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Adam Kretowski
Adam Kretowski
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland
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Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland
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Katarzyna Siewko
Katarzyna Siewko
Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
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patients (12 in the placebo arm and 13 in the RTX arm), 21 completed the primary endpoint of 24 weeks and 19/21 completed the 52-week observation. Both groups were similar at baseline with regard to age, sex, smoking status, prior corticosteroid treatment
Legh Wilkinson
Legh Wilkinson
Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa
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Nicolette J D Verhoog
Nicolette J D Verhoog
Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa
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Ann Louw
Ann Louw
Department of Biochemistry, Stellenbosch University, Stellenbosch, South Africa
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systemic administration of potent corticosteroid ( 61 ) Systemic lupus erythematosus (SLE) PBMCs Reduced N.D Diminished GC sensitivity ( 62 , 63 , 64 ) Inflammatory bowel disease (IBD) PBMCs Reduced N.C Impaired
M P Schuijt
M P Schuijt
Department of Laboratory Medicine, Slingeland Hospital, Doetinchem, The Netherlands
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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C G J Sweep
C G J Sweep
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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R van der Steen
R van der Steen
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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A J Olthaar
A J Olthaar
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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N M M L Stikkelbroeck
N M M L Stikkelbroeck
Division of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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H A Ross
H A Ross
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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A E van Herwaarden
A E van Herwaarden
Department of Laboratory Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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hormone-binding globulin (SHBG) or weakly bound to albumin, orosomucoid and corticosteroid-binding globulin ( 2 ). Only 1–4% circulates as free testosterone, which is considered to be the biologically active component ( 2 , 3 ). Determination of free
Jonneke J Hollanders
Jonneke J Hollanders
Department of Pediatric Endocrinology, VU University Medical Center, Amsterdam, The Netherlands
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Bibian van der Voorn
Bibian van der Voorn
Department of Pediatric Endocrinology, VU University Medical Center, Amsterdam, The Netherlands
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Noera Kieviet
Noera Kieviet
Department of Pediatrics, Psychiatry Obstetrics Pediatrics Expert Center, OLVG West, Amsterdam, The Netherlands
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Koert M Dolman
Koert M Dolman
Department of Pediatrics, Psychiatry Obstetrics Pediatrics Expert Center, OLVG West, Amsterdam, The Netherlands
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Yolanda B de Rijke
Yolanda B de Rijke
Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
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Erica L T van den Akker
Erica L T van den Akker
Department of Pediatric Endocrinology, Erasmus MC Sophia Children’s Hospital, Rotterdam, The Netherlands
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Joost Rotteveel
Joost Rotteveel
Department of Pediatric Endocrinology, VU University Medical Center, Amsterdam, The Netherlands
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Adriaan Honig
Adriaan Honig
Department of Pediatrics, Psychiatry Obstetrics Pediatrics Expert Center, OLVG West, Amsterdam, The Netherlands
Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
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Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
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Martijn J J Finken
Martijn J J Finken
Department of Pediatric Endocrinology, VU University Medical Center, Amsterdam, The Netherlands
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trimester, (5) use of systemic corticosteroids during pregnancy, (6) if participating in this study would interfere with regular care or (7) use of psychotropic medication. The study was approved by the medical ethics committees of the OLVG West Hospital
