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institution. Measurement of the thyroid function The plasma levels of the TSH, free tri-iodothyronine (T 3 ), and free thyroxine (T 4 ) were measured using an electrochemiluminescence immunoassay (Cobas 8000; Roche Diagnostics). The reference ranges

accurately reflect the natural direct secretion pattern of both thyroid hormones triiodothyronine (T 3 ) and thyroxine (T 4 ) by the thyroid gland (6, 7) . Unlike other drugs, dosing of l -T 4 is not fixed but has to be titrated according to individual

triiodothyronine (total T 3 ) antibody coated tube ( 125 I RIA kit); and a free triiodothyronine (free T 3 ) antibody coated tube ( 125 I RIA kit) (MP Biomedicals, Santa Ana, CA, USA), following the manufacturer’s instructions. Cell culture The C2C12

subclinical hypothyroid patients No significant difference in ADP levels between the groups 53 controls ↑ ADP after normalization of thyroid status ↑, Increase; ↓, decrease; ↔, no change; ADP, adiponectin; fT 4 , free thyroxine; fT 3 , free triiodothyronine

impaired bioactivity of circulating TSH has been prevalently demonstrated by in vitro bioassays ( 15 ), but this phenomenon can also be supported in vivo by the impaired increment of circulating free T4 and/or T3 following the TSH response upon TRH

–4 months and reached normal free triiodothyronine (FT 3 ) and free thyroxine (FT 4 ) levels. GD patients in remission had been treated with MMI for at least 10 months and maintained FT 3 , FT 4 , TSH and TRAb levels in normal range for at least 3 months

proton binding site, and several hydrophobic residues ( 5 , 6 , 7 ). The highest amount of this protein is located in the inner mitochondrial membrane of brown adipocytes, where, upon activation by free fatty acids, it drives the uncoupling of oxidative

drug use, and history of smoking were recorded. Clinical data including serum free triiodothyronine 3 (FT3), free triiodothyronine 4 (FT4), thyroid-stimulating hormone (TSH), and thyrotropin receptor antibody (TRAb) levels were measured to assess

( 55 ). Additionally, animal models nicely demonstrate that tri-iodothyronine (T3) directly acts on free FA uptake and oxidation in the myocardium ( 56 ). Decreased rates of whole-body energy metabolism in hypothyroid state result in reduced lipid

exception of two samples, which were analyzed for thyroid hormones in March 2017. The thyroid hormones triiodothyronine (T 3 ), free triiodothyronine (fT 3 ), thyroxine (T 4 ) and free thyroxine (fT 4 ) were measured by competitive electrochemiluminescence