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Piera Rizzolo, Valentina Silvestri, Virginia Valentini, Veronica Zelli, Agostino Bucalo, Ines Zanna, Simonetta Bianchi, Maria Grazia Tibiletti, Antonio Russo, Liliana Varesco, Gianluca Tedaldi, Bernardo Bonanni, Jacopo Azzollini, Siranoush Manoukian, Anna Coppa, Giuseppe Giannini, Laura Cortesi, Alessandra Viel, Marco Montagna, Paolo Peterlongo, Paolo Radice, Domenico Palli and Laura Ottini

women has been reported in some populations ( 18 , 19 , 20 ); however, more recent meta-analyses showed that there is no overall effect on FBC risk ( 21 , 22 , 23 ). In line with these meta-analysis studies, our study provides no evidence that CYP1B

Open access

Stefan Pilz, Armin Zittermann, Christian Trummer, Verena Theiler-Schwetz, Elisabeth Lerchbaum, Martin H Keppel, Martin R Grübler, Winfried März and Marlene Pandis

supplementation such as the Vitamin D Assessment (ViDA) Study in 5108 older individuals randomized to 2500 µg (100,000 IU) of vitamin D per month or placebo did not report on increased risk of fractures or falls ( 128 , 129 ). In line with this, a recent meta-analysis

Open access

T P McVeigh, R J Mulligan, U M McVeigh, P W Owens, N Miller, M Bell, F Sebag, C Guerin, D S Quill, J B Weidhaas, M J Kerin and A J Lowery

remained ill-defined. A recent meta-analysis has revisited the possibility of such an association and has confirmed the existence of, and quantified the increased co-occurrence of breast and differentiated thyroid cancer (DTC) ( 1 ). Both cancers occur

Open access

S Westra, Y H M Krul-Poel, H J van Wijland, M M ter Wee, F Stam, P Lips, F Pouwer and S Simsek

-to-moderate positive effect of short-term vitamin D supplementation on HRQOL in diseased people ( 28 ). However, no meta-analysis could be done due to the great heterogeneity in study samples, dose and type of vitamin D supplementation and the variation of HRQOL

Open access

Malin Nylander, Signe Frøssing, Caroline Kistorp, Jens Faber and Sven O Skouby

endothelial dysfunction, which is associated with an increased risk of cardiovascular disease (CVD) ( 4 ). PCOS is associated with both CVD and venous thromboembolism (VTE). A recent meta-analysis found an odds ratio of 1.44 (1.13–1.84) for coronary heart

Open access

M Jensterle, A Podbregar, K Goricar, N Gregoric and A Janez

meta-analysis that was limited to small studies with short-term follow-up and heterogeneous study designs ( 3 , 20 ). Its impact was generally related to the magnitude of WR. Five per cent of weight loss with LSM was associated with the 2 mmol

Open access

Klaudia Zajkowska, Janusz Kopczyński, Stanisław Góźdź and Aldona Kowalska

introduction of the new nomenclature, it appears that the initial calculations were overestimated ( 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ). According to the meta-analysis conducted by Bychkov et al . (25 studies, 46

Open access

Alessandra Gambineri and Carla Pelusi

). Observational cross-sectional studies performed on PCOS and included by Moran et al. in a meta-analysis estimate that the odds of T2DM are four times as high for women with PCOS compared with controls ( 12 ). A subgroup matched for BMI confirmed that the odds

Open access

Yael Sofer, Nava Nevo, Michal Vechoropoulos, Gabi Shefer, Etty Osher, Nathan Landis, Karen Tordjman, Geoffrey L Hammond and Naftali Stern

waist circumference ( 12 ). A meta-analysis of more than ten prospective studies has demonstrated that women with SHBG levels higher than 60 nmol/L had 80% lower risk of type 2 diabetes ( 7 ). Men with SHBG higher than 28.3 nmol/L had a 52% smaller risk

Open access

Katherine A Bolton, Kelly A Avery-Kiejda, Elizabeth G Holliday, John Attia, Nikola A Bowden and Rodney J Scott

cancer cases and 7771 controls ( 18 ). A meta-analysis conducted recently on the effect of this repeat on the risk of developing breast cancer (which included 11 studies of various ethnicity groups with a total of 7047 cases and 12,096 controls) reported